rewirebio.iobenchmarks
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Zero-shot benchmarking of RNA language models: Supplementary Information

bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973 · Peer-reviewed

DOI: 10.1093/bib/bbag098

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Records in this release that cite this source. A record can cite several sources.

Results

Values as the source printed them. Compare results only under compatible protocols, datasets and metrics.

ValueMetricModel or configurationDatasetEvaluation
0.571±0.002 unitlessOne minus overlap ratio (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, 1 − OR, sampled-mean)
0.763±0.001 unitlessAUROC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, AUC, sampled-mean)
0.705±0.001 unitlessF1 (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, F1, sampled-mean)
0.325±0.007 unitlessMCC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, MCC, sampled-mean)
0.534±0.001 unitlessOne minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, 1 − OR, sampled-mean)
0.740±0.001 unitlessAUROC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, AUC, sampled-mean)
0.696±0.001 unitlessF1 (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, F1, sampled-mean)
0.306±0.008 unitlessMCC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K3) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, MCC, sampled-mean)
0.535±0.037 unitlessAUROC (PLL-D; mean over assays)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, mean)
0.517 unitlessAUROC (PLL-D; median over assays)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, median)
0.053±0.055 unitlessMCC (PLL-D; mean over assays)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, mean)
0.022 unitlessMCC (PLL-D; median over assays)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, median)
0.066±0.065 unitlessAbsolute spearman correlation (PLL-D; mean over assays)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, mean)
0.043 unitlessAbsolute spearman correlation (PLL-D; median over assays)3UTRBERT (K3) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)
0.291±0.003 unitlessOne minus overlap ratio (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, 1 − OR, sampled-mean)
0.621±0.001 unitlessAUROC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, AUC, sampled-mean)
0.667±0.000 unitlessF1 (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, F1, sampled-mean)
0.025±0.003 unitlessMCC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, MCC, sampled-mean)
0.307±0.005 unitlessOne minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, 1 − OR, sampled-mean)
0.623±0.002 unitlessAUROC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, AUC, sampled-mean)
0.667±0.000 unitlessF1 (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, F1, sampled-mean)
0.015±0.003 unitlessMCC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K3) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K3) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, MCC, sampled-mean)
0.022±0.027 unitlessF1 (attention; mean over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS test set (70 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)
0.013 unitlessF1 (attention; median over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS test set (70 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, median)
0.004±0.030 unitlessMCC (attention; mean over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS test set (70 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)
-0.002 unitlessMCC (attention; median over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS test set (70 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, median)
0.014±0.015 unitlessF1 (attention; mean over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS-Hard test set (15 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, F1 score, mean)
0.008 unitlessF1 (attention; median over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS-Hard test set (15 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, F1 score, median)
0.000±0.014 unitlessMCC (attention; mean over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS-Hard test set (15 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, MCC, mean)
-0.001 unitlessMCC (attention; median over structures)3UTRBERT (K3) (zero-shot, Wang et al. 2026)TS-Hard test set (15 PDB structures) (Wang et al. 2026)3UTRBERT (K3) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, MCC, median)
0.626±0.001 unitlessOne minus overlap ratio (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, 1 − OR, sampled-mean)
0.795±0.001 unitlessAUROC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, AUC, sampled-mean)
0.722±0.001 unitlessF1 (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, F1, sampled-mean)
0.392±0.008 unitlessMCC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (CLS embedding, MCC, sampled-mean)
0.486±0.000 unitlessOne minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, 1 − OR, sampled-mean)
0.691±0.001 unitlessAUROC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, AUC, sampled-mean)
0.676±0.001 unitlessF1 (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, F1, sampled-mean)
0.176±0.009 unitlessMCC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RfamSample (561 Rfam families) (Wang et al. 2026)3UTRBERT (K4) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, MCC, sampled-mean)
0.550±0.037 unitlessAUROC (PLL-D; mean over assays)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, mean)
0.548 unitlessAUROC (PLL-D; median over assays)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, median)
0.076±0.059 unitlessMCC (PLL-D; mean over assays)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, mean)
0.075 unitlessMCC (PLL-D; median over assays)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, median)
0.100±0.077 unitlessAbsolute spearman correlation (PLL-D; mean over assays)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, mean)
0.093 unitlessAbsolute spearman correlation (PLL-D; median over assays)3UTRBERT (K4) (zero-shot, Wang et al. 2026)RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)
0.326±0.003 unitlessOne minus overlap ratio (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K4) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, 1 − OR, sampled-mean)
0.640±0.001 unitlessAUROC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K4) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, AUC, sampled-mean)
0.667±0.000 unitlessF1 (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K4) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, F1, sampled-mean)
0.003±0.003 unitlessMCC (CLS embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K4) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (CLS embedding, MCC, sampled-mean)
0.371±0.002 unitlessOne minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K4) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, 1 − OR, sampled-mean)
0.647±0.001 unitlessAUROC (FFT embedding; mean over random samplings of sequence pairs)3UTRBERT (K4) (zero-shot, Wang et al. 2026)ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)3UTRBERT (K4) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, AUC, sampled-mean)

Models, benchmarks and other records

Models (14)

Configurations (40)

Benchmarks (1)

Protocols (36)

Evaluations (1,190)

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18 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
attributes.artifact_sha256
c8fc78c3d8538c9431fc0448a4068a7643dfb7d74558877fd40b36feba71e214
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

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Version: bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973
Retrieved: 2026-10-11T21:27:04Z

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Artifact url
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12963973/supplementaryFiles
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

Original source ↗

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Version: bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973
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Doi
10.1093/bib/bbag098
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

Original source ↗

No field-specific location recorded

Version: bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973
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CC-BY-4.0
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Zero-shot benchmarking of RNA language models: Supplementary Information

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Limitations
2 values
  • The upward arrows in the column headers are in a symbol font and are lost in the text runs; directions are taken from the Methods.
  • Bold marks (best per model class) are not recorded.
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

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Version: bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973
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application/vnd.openxmlformats-officedocument.wordprocessingml.document
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

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Publication status
peer_reviewed
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Zero-shot benchmarking of RNA language models: Supplementary Information

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Retrieved at
2026-10-11T21:27:04Z
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Zero-shot benchmarking of RNA language models: Supplementary Information

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Url
https://doi.org/10.1093/bib/bbag098
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

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Version
bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973
Source metadata
Zero-shot benchmarking of RNA language models: Supplementary Information

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Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

Primary source retrieved and hashed for the 2026-10-11 RNA and other-omics literature pass.

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Stable ID: lit-rna-20261011-rnalm-zeroshot-source-wang2026-supplement

areas
rna-transcriptomes
contexts
research
url
https://doi.org/10.1093/bib/bbag098
artifact url
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12963973/supplementaryFiles
version
bbag098_supplymentary_information_20260209.docx from the Europe PMC supplementary files archive for PMC12963973
retrieved at
2026-10-11T21:27:04Z
artifact sha256
c8fc78c3d8538c9431fc0448a4068a7643dfb7d74558877fd40b36feba71e214
doi
10.1093/bib/bbag098
publication status
peer_reviewed
licence
CC-BY-4.0
media type
application/vnd.openxmlformats-officedocument.wordprocessingml.document
limitations
The upward arrows in the column headers are in a symbol font and are lost in the text runs; directions are taken from the Methods.; Bold marks (best per model class) are not recorded.
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