rewirebio.iobenchmarks
Protocol

Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)

Zero-shot: pseudo-log-likelihood difference from token logits; SR reported as median over assays (Supplementary Table 11).

35 evaluations · 35 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

35 recorded evaluations, 35 metric rows. A comparison chart has not yet been validated for these results. The table retains the individual findings and their sources.

View coverage and remaining gaps across all benchmarks

Results

Results are available, but no reviewed comparison panel is linked in this release.

All evaluations

35 evaluations · 35 results. Different protocols are not a single leaderboard.

Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays) · Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)

Sorted by Absolute spearman correlation (PLL-D; median over assays) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationAbsolute spearman correlation (PLL-D; median over assays)
EVO1.5 (8k_base) (zero-shot, Wang et al. 2026)Evaluation0.178 (best in column)
AIDO.RNA (1.6B) (zero-shot, Wang et al. 2026)Evaluation0.136
RiNALMo (mega) (zero-shot, Wang et al. 2026)Evaluation0.135
Uni-RNA (L8) (zero-shot, Wang et al. 2026)Evaluation0.133
RiNALMo (giga) (zero-shot, Wang et al. 2026)Evaluation0.114
RFamLlama (Base) (zero-shot, Wang et al. 2026)Evaluation0.11
AIDO.RNA (650M) (zero-shot, Wang et al. 2026)Evaluation0.106
Uni-RNA (L12) (zero-shot, Wang et al. 2026)Evaluation0.106
EVO1 (8k_base) (zero-shot, Wang et al. 2026)Evaluation0.105
LAMAR (2k) (zero-shot, Wang et al. 2026)Evaluation0.104
RNA-FM (zero-shot, Wang et al. 2026)Evaluation0.103
GenerRNA (zero-shot, Wang et al. 2026)Evaluation0.097
RFamLlama (Large) (zero-shot, Wang et al. 2026)Evaluation0.097
LAMAR (4k) (zero-shot, Wang et al. 2026)Evaluation0.095
DGRNA (zero-shot, Wang et al. 2026)Evaluation0.094
3UTRBERT (K4) (zero-shot, Wang et al. 2026)Evaluation0.093
LucaOne (D17.6M) (zero-shot, Wang et al. 2026)Evaluation0.091
Uni-RNA (L16) (zero-shot, Wang et al. 2026)Evaluation0.087
DNABERT-2 (zero-shot, Wang et al. 2026)Evaluation0.086
RiNALMo (micro) (zero-shot, Wang et al. 2026)Evaluation0.086
NT (zero-shot, Wang et al. 2026)Evaluation0.085
ProtRNA (zero-shot, Wang et al. 2026)Evaluation0.084
PlantRNA-FM (zero-shot, Wang et al. 2026)Evaluation0.083
RNAErnie (zero-shot, Wang et al. 2026)Evaluation0.081
LucaOne (G36.8M) (zero-shot, Wang et al. 2026)Evaluation0.079
SpliceBERT (zero-shot, Wang et al. 2026)Evaluation0.079
MP-RNA (zero-shot, Wang et al. 2026)Evaluation0.077
3UTRBERT (K6) (zero-shot, Wang et al. 2026)Evaluation0.073
DNABERT (k=3) (zero-shot, Wang et al. 2026)Evaluation0.068
LucaOne (D36.0M) (zero-shot, Wang et al. 2026)Evaluation0.068
DNABERT (k=6) (zero-shot, Wang et al. 2026)Evaluation0.067
RNABERT (zero-shot, Wang et al. 2026)Evaluation0.067
UTR_LM (zero-shot, Wang et al. 2026)Evaluation0.067
3UTRBERT (K5) (zero-shot, Wang et al. 2026)Evaluation0.065
3UTRBERT (K3) (zero-shot, Wang et al. 2026)Evaluation0.043
All 35 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: 3UTRBERT (K3) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.043 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row '3UTRBERT (K3)', column 'SR' (Median)
Configuration: 3UTRBERT (K4) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.093 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K4) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row '3UTRBERT (K4)', column 'SR' (Median)
Configuration: 3UTRBERT (K5) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.065 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K5) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row '3UTRBERT (K5)', column 'SR' (Median)
Configuration: 3UTRBERT (K6) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.073 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K6) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row '3UTRBERT (K6)', column 'SR' (Median)
Configuration: AIDO.RNA (1.6B) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.136 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (1.6B) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'AIDO.RNA (1.6B)', column 'SR' (Median)
Configuration: AIDO.RNA (650M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.106 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (650M) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'AIDO.RNA (650M)', column 'SR' (Median)
Configuration: DGRNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.094 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DGRNA zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'DGRNA', column 'SR' (Median)
Configuration: DNABERT-2 (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.086 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT-2 zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'DNABERT-2', column 'SR' (Median)
Configuration: DNABERT (k=3) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.068 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT (k=3) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'DNABERT (k=3)', column 'SR' (Median)
Configuration: DNABERT (k=6) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.067 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT (k=6) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'DNABERT (k=6)', column 'SR' (Median)
Configuration: EVO1.5 (8k_base) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.178 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EVO1.5 (8k_base) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'EVO1.5 (8k_base)', column 'SR' (Median)
Configuration: EVO1 (8k_base) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.105 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EVO1 (8k_base) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'EVO1 (8k_base)', column 'SR' (Median)
Configuration: GenerRNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.097 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GenerRNA zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'GenerRNA', column 'SR' (Median)
Configuration: LAMAR (2k) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.104 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LAMAR (2k) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'LAMAR (2k)', column 'SR' (Median)
Configuration: LAMAR (4k) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.095 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LAMAR (4k) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'LAMAR (4k)', column 'SR' (Median)
Configuration: LucaOne (D17.6M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.091 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (D17.6M) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'LucaOne (D17.6M)', column 'SR' (Median)
Configuration: LucaOne (D36.0M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.068 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (D36.0M) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'LucaOne (D36.0M)', column 'SR' (Median)
Configuration: LucaOne (G36.8M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.079 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (G36.8M) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'LucaOne (G36.8M)', column 'SR' (Median)
Configuration: MP-RNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.077 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

MP-RNA zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'MP-RNA', column 'SR' (Median)
Configuration: NT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.085 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'NT', column 'SR' (Median)
Configuration: PlantRNA-FM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.083 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

PlantRNA-FM zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'PlantRNA-FM', column 'SR' (Median)
Configuration: ProtRNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.084 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ProtRNA zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'ProtRNA', column 'SR' (Median)
Configuration: RFamLlama (Base) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.11 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RFamLlama (Base) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RFamLlama (Base)', column 'SR' (Median)
Configuration: RFamLlama (Large) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.097 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RFamLlama (Large) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RFamLlama (Large)', column 'SR' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.114 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'SR' (Median)

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Methods and evaluation design

Procedure, tasks and evaluated configurations

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Explore all linked results

Baseline coverage

Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.

0 of 2 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.

No execution recipe linked to this protocol. Recipe availability does not establish a completed evaluation.

External evaluations
35

Literature evidence is not a Rewire measurement. Executed but unpublished runs and private review status are not included.

Null control

Proposed control: requires review

Protocol-valid seeded random ranking; no fitting on assay labels

Protocol-specific applicability, permitted inputs, access, split, evaluator and execution requirements need review before implementation or execution.

This is a suggested selection rule, not a validated method or a measured score.

Conventional reference

Proposed control: requires review

Established label-free reference with explicitly permitted sequence/MSA inputs

Protocol-specific applicability, permitted inputs, access, split, evaluator and execution requirements need review before implementation or execution.

This is a suggested selection rule, not a validated method or a measured score.

Protocol coverage CSV (gzip) · Model evaluation matrix (gzip) · Source table (gzip) · Release and checksums (gzip)

Coverage is derived from release 2026-10-22-1b7cf027e4f6. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.

Run instructions

No runnable recipe has been reviewed for this protocol. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.

Strengths, limitations and unresolved questions

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

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Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
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Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

areas
rna-transcriptomes
contexts
research
protocol
Zero-shot: pseudo-log-likelihood difference from token logits. Metric SR, median over assays.
version
Wang et al. 2026
metric
absolute-spearman-correlation
metric direction
higher
unit
unitless
metric qualifier
PLL-D; median over assays
source locator
Supplementary Table 11 caption and column 'SR'; main text Methods
limitations
Zero-shot only; no fine-tuning or task head.; Binarisation for MCC, F1 and AUC in the fitness task is not described in the main text or supplement.
Related records

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