rewirebio.iobenchmarks
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RiNALMo (giga) (zero-shot, Wang et al. 2026)

RiNALMo (giga) evaluated zero-shot by Wang et al. 2026.

36 evaluations · 36 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

36 evaluations · 36 results. Different protocols are not a single leaderboard.

Sorted by AUROC (CLS embedding; mean over random samplings of sequence pairs) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationProtocol and datasetAUROC (CLS embedding; mean over random samplings of sequence pairs)AUROC (FFT embedding; mean over random samplings of sequence pairs)F1 (attention; mean over structures)F1 (attention; median over structures)F1 (CLS embedding; mean over random samplings of sequence pairs)F1 (FFT embedding; mean over random samplings of sequence pairs)MCC (attention; mean over structures)MCC (attention; median over structures)MCC (CLS embedding; mean over random samplings of sequence pairs)MCC (FFT embedding; mean over random samplings of sequence pairs)One minus overlap ratio (CLS embedding; mean over random samplings of sequence pairs)One minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)Absolute spearman correlation (PLL-D; mean over assays)Absolute spearman correlation (PLL-D; median over assays)Absolute spearman correlation (WT-LLR; mean over assays)Absolute spearman correlation (WT-LLR; median over assays)AUROC (PLL-D; mean over assays)AUROC (PLL-D; median over assays)AUROC (WT-LLR; mean over assays)AUROC (WT-LLR; median over assays)MCC (PLL-D; mean over assays)MCC (PLL-D; median over assays)MCC (WT-LLR; mean over assays)MCC (WT-LLR; median over assays)
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, AUC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)0.901±0.000 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, AUC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)0.721±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.587±0.079Not reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.547Not reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.137±0.118Not reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.095
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.175±0.165Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.095Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.581±0.075Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.552Not reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.116±0.108Not reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.075Not reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.167±0.151Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.114Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reported0.414±0.255 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (median over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reported0.404 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported0.423±0.257 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (median over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.416 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (mean over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reported0.365±0.214Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (median over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reported0.337Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (mean over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported0.375±0.222Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (median over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.347Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.790±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, AUC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reported0.896±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, F1 (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reported0.824±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, MCC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.657±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.553±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, AUC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reported0.705±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, F1 (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reported0.667±0.000Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, MCC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.000±0.000Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, 1 − OR (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.803±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, F1 (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reported0.836±0.000 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, MCC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.667±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, 1 − OR (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.591±0.002Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, F1 (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reported0.675±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RiNALMo (giga) (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, MCC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.332±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
All 36 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.587±0.079 AUROC (WT-LLR; mean over assays)
unitless · higher

Uncertainty: SD 0.079

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, AUC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-auc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RiNALMo (giga)', column 'AUC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.547 AUROC (WT-LLR; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, AUC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-auc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RiNALMo (giga)', column 'AUC' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.137±0.118 MCC (WT-LLR; mean over assays)
unitless · higher

Uncertainty: SD 0.118

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RiNALMo (giga)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.095 MCC (WT-LLR; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RiNALMo (giga)', column 'MCC' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.175±0.165 Absolute spearman correlation (WT-LLR; mean over assays)
unitless · higher

Uncertainty: SD 0.165

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, SR, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-sr-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RiNALMo (giga)', column 'SR' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.095 Absolute spearman correlation (WT-LLR; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RiNALMo (giga)', column 'SR' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.581±0.075 AUROC (PLL-D; mean over assays)
unitless · higher

Uncertainty: SD 0.075

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-auc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'AUC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.552 AUROC (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-auc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'AUC' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.116±0.108 MCC (PLL-D; mean over assays)
unitless · higher

Uncertainty: SD 0.108

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.075 MCC (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'MCC' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.167±0.151 Absolute spearman correlation (PLL-D; mean over assays)
unitless · higher

Uncertainty: SD 0.151

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'SR' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.114 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RiNALMo (giga)', column 'SR' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.414±0.255 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.255

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (giga)', column 'F1 score' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (median over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.404 F1 (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (giga)', column 'F1 score' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.423±0.257 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.257

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (giga)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (median over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.416 MCC (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (giga)', column 'MCC' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (mean over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0.365±0.214 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.214

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row 'RiNALMo (giga)', column 'F1 score' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (median over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0.337 F1 (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, F1 score, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-f1-score-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row 'RiNALMo (giga)', column 'F1 score' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (mean over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0.375±0.222 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.222

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row 'RiNALMo (giga)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (median over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0.347 MCC (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row 'RiNALMo (giga)', column 'MCC' (Median)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.790±0.001 One minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, 1 − OR, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-1-or-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row 'RiNALMo (giga)', column '1 − OR'
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, AUC (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.896±0.001 AUROC (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, AUC, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-auc-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row 'RiNALMo (giga)', column 'AUC'
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, F1 (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.824±0.001 F1 (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, F1, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-f1-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row 'RiNALMo (giga)', column 'F1'
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, MCC (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.657±0.001 MCC (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, MCC, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-mcc-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row 'RiNALMo (giga)', column 'MCC'
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs)
Dataset: ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)
0.553±0.001 One minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, 1 − OR, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t7-1-or-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 7, row 'RiNALMo (giga)', column '1 − OR'

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Stable ID: lit-rna-20261011-rnalm-zeroshot-config-rinalmo-giga-wang2026

areas
rna-transcriptomes
contexts
research
method types
foundation_model
reported name
RiNALMo (giga)
foundation model eligible
true
parameters
Pretrained weights used without fine-tuning (zero-shot); attention maps, embeddings or token logits read out as described in the Methods
access reuse
Public download location listed in Supplementary Table 1
source locator
Supplementary Table 1 row 'RiNALMo'
checkpoint
https://github.com/lbcb-sci/RiNALMo (downloaded 2024/7/26; version column 'micro (micro)/mega (mega)/giga (giga)'; variant label in results tables 'giga')
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giga
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