rewirebio.iobenchmarks
Protocol

Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)

Zero-shot: symmetrised, APC-corrected attention map from one head-layer and threshold chosen on VL1 by F1; MCC reported as mean over structures (Supplementary Table 4).

32 evaluations · 32 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

32 recorded evaluations, 32 metric rows. A comparison chart has not yet been validated for these results. The table retains the individual findings and their sources.

View coverage and remaining gaps across all benchmarks

Results

Results are available, but no reviewed comparison panel is linked in this release.

All evaluations

32 evaluations · 32 results. Different protocols are not a single leaderboard.

Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures) · Dataset: TS test set (70 PDB structures) (Wang et al. 2026)

Sorted by MCC (attention; mean over structures) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationMCC (attention; mean over structures)
RNA-MSM (zero-shot, Wang et al. 2026)Evaluation0.588±0.217 (best in column)
AIDO.RNA (1.6B) (zero-shot, Wang et al. 2026)Evaluation0.518±0.258
MP-RNA (zero-shot, Wang et al. 2026)Evaluation0.510±0.200
RNA-km (zero-shot, Wang et al. 2026)Evaluation0.501±0.233
AIDO.RNA (650M) (zero-shot, Wang et al. 2026)Evaluation0.427±0.235
RiNALMo (giga) (zero-shot, Wang et al. 2026)Evaluation0.423±0.257
ERNIE-RNA (zero-shot, Wang et al. 2026)Evaluation0.351±0.230
ProtRNA (zero-shot, Wang et al. 2026)Evaluation0.351±0.237
RiNALMo (mega) (zero-shot, Wang et al. 2026)Evaluation0.342±0.225
Uni-RNA (L16) (zero-shot, Wang et al. 2026)Evaluation0.311±0.200
RNAErnie (zero-shot, Wang et al. 2026)Evaluation0.290±0.221
RiNALMo (micro) (zero-shot, Wang et al. 2026)Evaluation0.275±0.184
RNA-FM (zero-shot, Wang et al. 2026)Evaluation0.273±0.239
LucaOne (G36.8M) (zero-shot, Wang et al. 2026)Evaluation0.268±0.238
Uni-RNA (L12) (zero-shot, Wang et al. 2026)Evaluation0.258±0.203
Uni-RNA (L8) (zero-shot, Wang et al. 2026)Evaluation0.258±0.202
LucaOne (D17.6M) (zero-shot, Wang et al. 2026)Evaluation0.228±0.196
LucaOne (D36.0M) (zero-shot, Wang et al. 2026)Evaluation0.214±0.203
PlantRNA-FM (zero-shot, Wang et al. 2026)Evaluation0.155±0.137
RFamLlama (Large) (zero-shot, Wang et al. 2026)Evaluation0.042±0.058
SpliceBERT (zero-shot, Wang et al. 2026)Evaluation0.033±0.045
RFamLlama (Base) (zero-shot, Wang et al. 2026)Evaluation0.031±0.045
LAMAR (2k) (zero-shot, Wang et al. 2026)Evaluation0.029±0.027
LAMAR (4k) (zero-shot, Wang et al. 2026)Evaluation0.025±0.039
UTR_LM (zero-shot, Wang et al. 2026)Evaluation0.016±0.037
RNABERT (zero-shot, Wang et al. 2026)Evaluation0.010±0.029
3UTRBERT (K5) (zero-shot, Wang et al. 2026)Evaluation0.007±0.040
3UTRBERT (K3) (zero-shot, Wang et al. 2026)Evaluation0.004±0.030
3UTRBERT (K6) (zero-shot, Wang et al. 2026)Evaluation0.003±0.032
3UTRBERT (K4) (zero-shot, Wang et al. 2026)Evaluation0.001±0.026
DNABERT (k=6) (zero-shot, Wang et al. 2026)Evaluation0.001±0.024
DNABERT (k=3) (zero-shot, Wang et al. 2026)Evaluation-0.008±0.025
All 32 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: 3UTRBERT (K3) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.004±0.030 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.030

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K3)', column 'MCC' (Mean ± Std)
Configuration: 3UTRBERT (K4) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.001±0.026 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.026

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K4) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K4)', column 'MCC' (Mean ± Std)
Configuration: 3UTRBERT (K5) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.007±0.040 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.040

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K5) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K5)', column 'MCC' (Mean ± Std)
Configuration: 3UTRBERT (K6) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.003±0.032 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.032

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K6) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K6)', column 'MCC' (Mean ± Std)
Configuration: AIDO.RNA (1.6B) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.518±0.258 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.258

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (1.6B) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'AIDO.RNA (1.6B)', column 'MCC' (Mean ± Std)
Configuration: AIDO.RNA (650M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.427±0.235 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.235

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (650M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'AIDO.RNA (650M)', column 'MCC' (Mean ± Std)
Configuration: DNABERT (k=3) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
-0.008±0.025 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.025

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT (k=3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'DNABERT (k=3)', column 'MCC' (Mean ± Std)
Configuration: DNABERT (k=6) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.001±0.024 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.024

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT (k=6) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'DNABERT (k=6)', column 'MCC' (Mean ± Std)
Configuration: ERNIE-RNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.351±0.230 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.230

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ERNIE-RNA zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'ERNIE-RNA', column 'MCC' (Mean ± Std)
Configuration: LAMAR (2k) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.029±0.027 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.027

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LAMAR (2k) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LAMAR (2k)', column 'MCC' (Mean ± Std)
Configuration: LAMAR (4k) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.025±0.039 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.039

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LAMAR (4k) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LAMAR (4k)', column 'MCC' (Mean ± Std)
Configuration: LucaOne (D17.6M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.228±0.196 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.196

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (D17.6M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LucaOne (D17.6M)', column 'MCC' (Mean ± Std)
Configuration: LucaOne (D36.0M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.214±0.203 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.203

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (D36.0M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LucaOne (D36.0M)', column 'MCC' (Mean ± Std)
Configuration: LucaOne (G36.8M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.268±0.238 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.238

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (G36.8M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LucaOne (G36.8M)', column 'MCC' (Mean ± Std)
Configuration: MP-RNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.510±0.200 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.200

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

MP-RNA zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'MP-RNA', column 'MCC' (Mean ± Std)
Configuration: PlantRNA-FM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.155±0.137 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.137

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

PlantRNA-FM zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'PlantRNA-FM', column 'MCC' (Mean ± Std)
Configuration: ProtRNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.351±0.237 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.237

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ProtRNA zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'ProtRNA', column 'MCC' (Mean ± Std)
Configuration: RFamLlama (Base) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.031±0.045 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.045

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RFamLlama (Base) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RFamLlama (Base)', column 'MCC' (Mean ± Std)
Configuration: RFamLlama (Large) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.042±0.058 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.058

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RFamLlama (Large) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RFamLlama (Large)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.423±0.257 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.257

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (giga)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (mega) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.342±0.225 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.225

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (mega) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (mega)', column 'MCC' (Mean ± Std)
Configuration: RiNALMo (micro) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.275±0.184 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.184

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (micro) zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (micro)', column 'MCC' (Mean ± Std)
Configuration: RNA-FM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.273±0.239 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.239

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNA-FM zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RNA-FM', column 'MCC' (Mean ± Std)
Configuration: RNA-km (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.501±0.233 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.233

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNA-km zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RNA-km', column 'MCC' (Mean ± Std)
Configuration: RNA-MSM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.588±0.217 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.217

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RNA-MSM zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RNA-MSM', column 'MCC' (Mean ± Std)

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Methods and evaluation design

Procedure, tasks and evaluated configurations

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Explore all linked results

Baseline coverage

Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.

0 of 2 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.

No execution recipe linked to this protocol. Recipe availability does not establish a completed evaluation.

Author-reported evaluations
1
External evaluations
31

Literature evidence is not a Rewire measurement. Executed but unpublished runs and private review status are not included.

Null control

Proposed control: requires review

Protocol-valid seeded random ranking; no fitting on assay labels

Protocol-specific applicability, permitted inputs, access, split, evaluator and execution requirements need review before implementation or execution.

This is a suggested selection rule, not a validated method or a measured score.

Conventional reference

Proposed control: requires review

Established label-free reference with explicitly permitted sequence/MSA inputs

Protocol-specific applicability, permitted inputs, access, split, evaluator and execution requirements need review before implementation or execution.

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Coverage is derived from release 2026-10-22-1b7cf027e4f6. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.

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Evidence table

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Technical metadata and extraction receipts

Stable ID: lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

areas
rna-transcriptomes
contexts
research
protocol
Zero-shot: symmetrised, APC-corrected attention map from one head-layer and threshold chosen on VL1 by F1. Metric MCC, mean over structures.
version
Wang et al. 2026
metric
matthews-correlation-coefficient
metric direction
higher
unit
unitless
metric qualifier
attention; mean over structures
source locator
Supplementary Table 4 caption and column 'MCC'; main text Methods
limitations
Zero-shot only; no fine-tuning or task head.; Base pairs come from 3D structures; one head-layer and threshold per model chosen on VL1.
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