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RNABERT (zero-shot, Wang et al. 2026)

RNABERT evaluated zero-shot by Wang et al. 2026.

36 evaluations · 36 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

36 evaluations · 36 results. Different protocols are not a single leaderboard.

Sorted by AUROC (CLS embedding; mean over random samplings of sequence pairs) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationProtocol and datasetAUROC (CLS embedding; mean over random samplings of sequence pairs)AUROC (FFT embedding; mean over random samplings of sequence pairs)F1 (attention; mean over structures)F1 (attention; median over structures)F1 (CLS embedding; mean over random samplings of sequence pairs)F1 (FFT embedding; mean over random samplings of sequence pairs)MCC (attention; mean over structures)MCC (attention; median over structures)MCC (CLS embedding; mean over random samplings of sequence pairs)MCC (FFT embedding; mean over random samplings of sequence pairs)One minus overlap ratio (CLS embedding; mean over random samplings of sequence pairs)One minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)Absolute spearman correlation (PLL-D; mean over assays)Absolute spearman correlation (PLL-D; median over assays)Absolute spearman correlation (WT-LLR; mean over assays)Absolute spearman correlation (WT-LLR; median over assays)AUROC (PLL-D; mean over assays)AUROC (PLL-D; median over assays)AUROC (WT-LLR; mean over assays)AUROC (WT-LLR; median over assays)MCC (PLL-D; mean over assays)MCC (PLL-D; median over assays)MCC (WT-LLR; mean over assays)MCC (WT-LLR; median over assays)
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, AUC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)0.831±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, AUC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)0.741±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.549±0.046Not reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.532Not reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.071±0.067Not reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.044
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.100±0.086Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.075Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.544±0.041Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.534Not reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.065±0.063Not reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.047Not reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (mean over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.090±0.086Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays), RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.067Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reported0.022±0.032 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (median over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reported0 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported0.010±0.029 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (median over structures), TS test set (70 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported-0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (mean over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reported0.014±0.026Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (median over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reported0 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (mean over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported0.007±0.023Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (median over structures), TS-Hard test set (15 PDB structures) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported-0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.724±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, AUC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reported0.777±0.002 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, F1 (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reported0.794±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, MCC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.586±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.585±0.002Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, AUC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reported0.732±0.002Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, F1 (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reported0.719±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, MCC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.363±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, 1 − OR (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.730±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, F1 (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reported0.797±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), CLS embedding, MCC (mean over repeated random samplings of sequence pairs), RfamSample (561 Rfam families) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.588±0.001 (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, 1 − OR (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.561±0.002Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, F1 (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reported0.710±0.001Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
RNABERT (zero-shot, Wang et al. 2026)EvaluationWang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), CLS embedding, MCC (mean over repeated random samplings of sequence pairs), ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported0.350±0.002Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
All 36 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.549±0.046 AUROC (WT-LLR; mean over assays)
unitless · higher

Uncertainty: SD 0.046

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, AUC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-auc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RNABERT', column 'AUC' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, AUC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.532 AUROC (WT-LLR; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, AUC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-auc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RNABERT', column 'AUC' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.071±0.067 MCC (WT-LLR; mean over assays)
unitless · higher

Uncertainty: SD 0.067

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RNABERT', column 'MCC' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, MCC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.044 MCC (WT-LLR; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RNABERT', column 'MCC' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.100±0.086 Absolute spearman correlation (WT-LLR; mean over assays)
unitless · higher

Uncertainty: SD 0.086

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, SR, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-sr-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RNABERT', column 'SR' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), WT-LLR, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.075 Absolute spearman correlation (WT-LLR; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (WT-LLR, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t10-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 10, row 'RNABERT', column 'SR' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.544±0.041 AUROC (PLL-D; mean over assays)
unitless · higher

Uncertainty: SD 0.041

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-auc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RNABERT', column 'AUC' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, AUC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.534 AUROC (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, AUC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-auc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RNABERT', column 'AUC' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.065±0.063 MCC (PLL-D; mean over assays)
unitless · higher

Uncertainty: SD 0.063

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RNABERT', column 'MCC' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, MCC (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.047 MCC (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RNABERT', column 'MCC' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (mean over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.090±0.086 Absolute spearman correlation (PLL-D; mean over assays)
unitless · higher

Uncertainty: SD 0.086

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RNABERT', column 'SR' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot fitness, RNAGym ncRNA DMS assays (31 assays), PLL-D, SR (median over assays)
Dataset: RNAGym ncRNA DMS assays (31 assays) (Wang et al. 2026)
0.067 Absolute spearman correlation (PLL-D; median over assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot fitness on RNAGym ncRNA DMS assays (31 assays) (PLL-D, SR, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t11-sr-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 11, row 'RNABERT', column 'SR' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.022±0.032 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.032

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '*RNABERT', column 'F1 score' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (median over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0 F1 (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '*RNABERT', column 'F1 score' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.010±0.029 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.029

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '*RNABERT', column 'MCC' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, MCC (median over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
-0.001 MCC (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS test set (70 PDB structures) (attention, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '*RNABERT', column 'MCC' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (mean over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0.014±0.026 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.026

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row '*RNABERT', column 'F1 score' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, F1 score (median over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0 F1 (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, F1 score, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-f1-score-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row '*RNABERT', column 'F1 score' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (mean over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
0.007±0.023 MCC (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.023

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, MCC, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-mcc-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row '*RNABERT', column 'MCC' (Mean ± Std)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS-Hard test set (15 PDB structures), attention, MCC (median over structures)
Dataset: TS-Hard test set (15 PDB structures) (Wang et al. 2026)
-0.001 MCC (attention; median over structures)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot secondary structure on TS-Hard test set (15 PDB structures) (attention, MCC, median)

lit-rna-20261011-rnalm-zeroshot-protocol-t5-mcc-median

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 5, row '*RNABERT', column 'MCC' (Median)
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.724±0.001 One minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, 1 − OR, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-1-or-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row '*RNABERT', column '1 − OR'
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, AUC (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.777±0.002 AUROC (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.002

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, AUC, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-auc-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row '*RNABERT', column 'AUC'
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, F1 (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.794±0.001 F1 (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, F1, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-f1-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row '*RNABERT', column 'F1'
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot family classification, RfamSample (561 Rfam families), FFT embedding, MCC (mean over repeated random samplings of sequence pairs)
Dataset: RfamSample (561 Rfam families) (Wang et al. 2026)
0.586±0.001 MCC (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.001

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot family classification on RfamSample (561 Rfam families) (FFT embedding, MCC, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t6-mcc-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 6, row '*RNABERT', column 'MCC'
Configuration: RNABERT (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot RNA type classification, ArchiveII-Nr (1273 RNAs), FFT embedding, 1 − OR (mean over repeated random samplings of sequence pairs)
Dataset: ArchiveII-Nr (1273 RNAs) (Wang et al. 2026)
0.585±0.002 One minus overlap ratio (FFT embedding; mean over random samplings of sequence pairs)
unitless · higher

Uncertainty: SD 0.002

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNABERT zero-shot RNA type classification on ArchiveII-Nr (1273 RNAs) (FFT embedding, 1 − OR, sampled-mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t7-1-or-sampled-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 7, row '*RNABERT', column '1 − OR'

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Stable ID: lit-rna-20261011-rnalm-zeroshot-config-rnabert-wang2026

areas
rna-transcriptomes
contexts
research
method types
foundation_model
reported name
RNABERT
foundation model eligible
true
parameters
Pretrained weights used without fine-tuning (zero-shot); attention maps, embeddings or token logits read out as described in the Methods
access reuse
Public download location listed in Supplementary Table 1
source locator
Supplementary Table 1 row 'RNABERT'
checkpoint
https://huggingface.co/multimolecule/rnabert (downloaded 2024/11/27; version column '-'; variant label in results tables 'none')
missing metadata
version: reason: unreported; note: No version column entry for this checkpoint in Supplementary Table 1
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