rewirebio.iobenchmarks
Protocol

Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)

Zero-shot: symmetrised, APC-corrected attention map from one head-layer and threshold chosen on VL1 by F1; F1 score reported as mean over structures (Supplementary Table 4).

32 evaluations · 32 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

32 recorded evaluations, 32 metric rows. A comparison chart has not yet been validated for these results. The table retains the individual findings and their sources.

View coverage and remaining gaps across all benchmarks

Results

Results are available, but no reviewed comparison panel is linked in this release.

All evaluations

32 evaluations · 32 results. Different protocols are not a single leaderboard.

Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures) · Dataset: TS test set (70 PDB structures) (Wang et al. 2026)

Sorted by F1 (attention; mean over structures) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationF1 (attention; mean over structures)
RNA-MSM (zero-shot, Wang et al. 2026)Evaluation0.582±0.217 (best in column)
AIDO.RNA (1.6B) (zero-shot, Wang et al. 2026)Evaluation0.508±0.263
MP-RNA (zero-shot, Wang et al. 2026)Evaluation0.507±0.201
RNA-km (zero-shot, Wang et al. 2026)Evaluation0.492±0.236
RiNALMo (giga) (zero-shot, Wang et al. 2026)Evaluation0.414±0.255
AIDO.RNA (650M) (zero-shot, Wang et al. 2026)Evaluation0.402±0.234
RiNALMo (mega) (zero-shot, Wang et al. 2026)Evaluation0.342±0.225
ProtRNA (zero-shot, Wang et al. 2026)Evaluation0.333±0.236
Uni-RNA (L16) (zero-shot, Wang et al. 2026)Evaluation0.307±0.197
ERNIE-RNA (zero-shot, Wang et al. 2026)Evaluation0.300±0.234
RNAErnie (zero-shot, Wang et al. 2026)Evaluation0.288±0.223
RiNALMo (micro) (zero-shot, Wang et al. 2026)Evaluation0.268±0.184
RNA-FM (zero-shot, Wang et al. 2026)Evaluation0.267±0.239
Uni-RNA (L12) (zero-shot, Wang et al. 2026)Evaluation0.258±0.198
Uni-RNA (L8) (zero-shot, Wang et al. 2026)Evaluation0.257±0.197
LucaOne (G36.8M) (zero-shot, Wang et al. 2026)Evaluation0.253±0.232
LucaOne (D17.6M) (zero-shot, Wang et al. 2026)Evaluation0.224±0.194
LucaOne (D36.0M) (zero-shot, Wang et al. 2026)Evaluation0.211±0.200
PlantRNA-FM (zero-shot, Wang et al. 2026)Evaluation0.160±0.137
RFamLlama (Large) (zero-shot, Wang et al. 2026)Evaluation0.052±0.057
SpliceBERT (zero-shot, Wang et al. 2026)Evaluation0.043±0.039
RFamLlama (Base) (zero-shot, Wang et al. 2026)Evaluation0.042±0.040
LAMAR (2k) (zero-shot, Wang et al. 2026)Evaluation0.037±0.021
LAMAR (4k) (zero-shot, Wang et al. 2026)Evaluation0.033±0.040
UTR_LM (zero-shot, Wang et al. 2026)Evaluation0.029±0.032
3UTRBERT (K5) (zero-shot, Wang et al. 2026)Evaluation0.023±0.034
3UTRBERT (K3) (zero-shot, Wang et al. 2026)Evaluation0.022±0.027
3UTRBERT (K6) (zero-shot, Wang et al. 2026)Evaluation0.022±0.012
RNABERT (zero-shot, Wang et al. 2026)Evaluation0.022±0.032
3UTRBERT (K4) (zero-shot, Wang et al. 2026)Evaluation0.018±0.027
DNABERT (k=6) (zero-shot, Wang et al. 2026)Evaluation0.017±0.021
DNABERT (k=3) (zero-shot, Wang et al. 2026)Evaluation0.011±0.019
All 32 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: 3UTRBERT (K3) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.022±0.027 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.027

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K3)', column 'F1 score' (Mean ± Std)
Configuration: 3UTRBERT (K4) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.018±0.027 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.027

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K4) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K4)', column 'F1 score' (Mean ± Std)
Configuration: 3UTRBERT (K5) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.023±0.034 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.034

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K5) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K5)', column 'F1 score' (Mean ± Std)
Configuration: 3UTRBERT (K6) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.022±0.012 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.012

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

3UTRBERT (K6) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row '3UTRBERT (K6)', column 'F1 score' (Mean ± Std)
Configuration: AIDO.RNA (1.6B) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.508±0.263 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.263

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (1.6B) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'AIDO.RNA (1.6B)', column 'F1 score' (Mean ± Std)
Configuration: AIDO.RNA (650M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.402±0.234 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.234

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (650M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'AIDO.RNA (650M)', column 'F1 score' (Mean ± Std)
Configuration: DNABERT (k=3) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.011±0.019 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.019

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT (k=3) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'DNABERT (k=3)', column 'F1 score' (Mean ± Std)
Configuration: DNABERT (k=6) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.017±0.021 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.021

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT (k=6) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'DNABERT (k=6)', column 'F1 score' (Mean ± Std)
Configuration: ERNIE-RNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.300±0.234 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.234

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ERNIE-RNA zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'ERNIE-RNA', column 'F1 score' (Mean ± Std)
Configuration: LAMAR (2k) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.037±0.021 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.021

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LAMAR (2k) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LAMAR (2k)', column 'F1 score' (Mean ± Std)
Configuration: LAMAR (4k) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.033±0.040 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.040

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LAMAR (4k) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LAMAR (4k)', column 'F1 score' (Mean ± Std)
Configuration: LucaOne (D17.6M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.224±0.194 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.194

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (D17.6M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LucaOne (D17.6M)', column 'F1 score' (Mean ± Std)
Configuration: LucaOne (D36.0M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.211±0.200 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.200

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (D36.0M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LucaOne (D36.0M)', column 'F1 score' (Mean ± Std)
Configuration: LucaOne (G36.8M) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.253±0.232 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.232

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LucaOne (G36.8M) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'LucaOne (G36.8M)', column 'F1 score' (Mean ± Std)
Configuration: MP-RNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.507±0.201 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.201

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

MP-RNA zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'MP-RNA', column 'F1 score' (Mean ± Std)
Configuration: PlantRNA-FM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.160±0.137 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.137

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

PlantRNA-FM zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'PlantRNA-FM', column 'F1 score' (Mean ± Std)
Configuration: ProtRNA (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.333±0.236 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.236

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ProtRNA zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'ProtRNA', column 'F1 score' (Mean ± Std)
Configuration: RFamLlama (Base) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.042±0.040 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.040

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RFamLlama (Base) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RFamLlama (Base)', column 'F1 score' (Mean ± Std)
Configuration: RFamLlama (Large) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.052±0.057 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.057

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RFamLlama (Large) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RFamLlama (Large)', column 'F1 score' (Mean ± Std)
Configuration: RiNALMo (giga) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.414±0.255 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.255

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (giga) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (giga)', column 'F1 score' (Mean ± Std)
Configuration: RiNALMo (mega) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.342±0.225 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.225

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (mega) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (mega)', column 'F1 score' (Mean ± Std)
Configuration: RiNALMo (micro) (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.268±0.184 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.184

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo (micro) zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RiNALMo (micro)', column 'F1 score' (Mean ± Std)
Configuration: RNA-FM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.267±0.239 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.239

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNA-FM zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RNA-FM', column 'F1 score' (Mean ± Std)
Configuration: RNA-km (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.492±0.236 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.236

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNA-km zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RNA-km', column 'F1 score' (Mean ± Std)
Configuration: RNA-MSM (zero-shot, Wang et al. 2026)Protocol: Wang et al. 2026 zero-shot secondary structure, TS test set (70 PDB structures), attention, F1 score (mean over structures)
Dataset: TS test set (70 PDB structures) (Wang et al. 2026)
0.582±0.217 F1 (attention; mean over structures)
unitless · higher

Uncertainty: SD 0.217

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

RNA-MSM zero-shot secondary structure on TS test set (70 PDB structures) (attention, F1 score, mean)

lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

Aggregation: Not reported

Zero-shot benchmarking of RNA language models: Supplementary Information; Zero-shot benchmarking of RNA language models in structural, functional, and evolutionary learning · Supplementary Table 4, row 'RNA-MSM', column 'F1 score' (Mean ± Std)

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Methods and evaluation design

Procedure, tasks and evaluated configurations

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Explore all linked results

Baseline coverage

Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.

0 of 2 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.

No execution recipe linked to this protocol. Recipe availability does not establish a completed evaluation.

Author-reported evaluations
1
External evaluations
31

Literature evidence is not a Rewire measurement. Executed but unpublished runs and private review status are not included.

Null control

Proposed control: requires review

Protocol-valid seeded random ranking; no fitting on assay labels

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Conventional reference

Proposed control: requires review

Established label-free reference with explicitly permitted sequence/MSA inputs

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This is a suggested selection rule, not a validated method or a measured score.

Protocol coverage CSV (gzip) · Model evaluation matrix (gzip) · Source table (gzip) · Release and checksums (gzip)

Coverage is derived from release 2026-10-22-1b7cf027e4f6. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.

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Strengths, limitations and unresolved questions

Evidence

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Evidence table

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Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: lit-rna-20261011-rnalm-zeroshot-protocol-t4-f1-score-mean

areas
rna-transcriptomes
contexts
research
protocol
Zero-shot: symmetrised, APC-corrected attention map from one head-layer and threshold chosen on VL1 by F1. Metric F1 score, mean over structures.
version
Wang et al. 2026
metric
f1-score
metric direction
higher
unit
unitless
metric qualifier
attention; mean over structures
source locator
Supplementary Table 4 caption and column 'F1 score'; main text Methods
limitations
Zero-shot only; no fine-tuning or task head.; Base pairs come from 3D structures; one head-layer and threshold per model chosen on VL1.
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