rewirebio.iobenchmarks
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Splice-MS1024

Published RNA language model backbone, fine-tuned per task by the BEACON authors under their protocol.

13 evaluations · 13 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

13 evaluations · 13 results. Different protocols are not a single leaderboard.

Sorted by R² (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationProtocol and datasetR²SpearmanAccuracyAUROCF1 (base pairs; binary F1 over all position pairs pooled across the test set; threshold 0.5)Mean columnwise RMSEPrecision at lSplice top k accuracy
Splice-MS1024EvaluationBEACON MRL: Mean ribosome loading prediction, Optimus (BEACON split)67.15(30.54) (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON APA: Alternative polyadenylation isoform prediction, APARENT (BEACON split)60.03(3.42)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON PRS: Programmable RNA switch prediction, Angenent-Mari's switch set (BEACON split)57.72(0.45)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON DMP: Distance map prediction, RNAcontact (BEACON split)55.89(0.48)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON SSI: Structure score imputation, StructureImpute (BEACON split)39.22(0.02)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON CMP: Contact map prediction, RNAcontact (BEACON split)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported47.32(3.16)%Not reported
Splice-MS1024EvaluationBEACON CRI-Off: CRISPR off-target effect prediction, DeepCRISPR (BEACON split)Not reported5.00(0.71)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON CRI-On: CRISPR on-target efficiency prediction, DeepCRISPR (BEACON split)Not reported27.59(4.61) (best in column)Not reportedNot reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON Modif: RNA modification site prediction, MultiRM (BEACON split)Not reportedNot reportedNot reported53.45(6.25)Not reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON ncRNA: Non-coding RNA family classification, Noorul's ncRNA set (BEACON split)Not reportedNot reported96.05(0.777)%Not reportedNot reportedNot reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON SPL: Splice site prediction, SpliceAI (BEACON split)Not reportedNot reportedNot reportedNot reportedNot reportedNot reportedNot reported48.52(0.49)%
Splice-MS1024EvaluationBEACON SSP: Secondary structure prediction, bpRNA-1m (BEACON split)Not reportedNot reportedNot reportedNot reported68.26(0.20)%Not reportedNot reportedNot reported
Splice-MS1024EvaluationBEACON VDP: Vaccine degradation prediction, OpenVaccine (BEACON split)Not reportedNot reportedNot reportedNot reportedNot reported0.313(0.000)Not reportedNot reported
All 13 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Splice-MS1024Task: BEACON APA: Alternative polyadenylation isoform prediction
Dataset subset: APARENT (BEACON split)
60.03(3.42) R²
unitless · higher

Uncertainty: SD 3.42

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON APA: Alternative polyadenylation isoform prediction

BEACON harness, fixed downstream head per task. Train/validation/test 145,463/33,170/49,755; dataset APARENT.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(APA)
Configuration: Splice-MS1024Task: BEACON CMP: Contact map prediction
Dataset subset: RNAcontact (BEACON split)
47.32(3.16)% Precision at l
percent · higher

Uncertainty: SD 3.16

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON CMP: Contact map prediction

BEACON harness, fixed downstream head per task. Train/validation/test 188/23/80; dataset RNAcontact.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(CMP)
Configuration: Splice-MS1024Task: BEACON CRI-Off: CRISPR off-target effect prediction
Dataset subset: DeepCRISPR (BEACON split)
5.00(0.71) Spearman
unitless · higher

Uncertainty: SD 0.71

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON CRI-Off: CRISPR off-target effect prediction

BEACON harness, fixed downstream head per task. Train/validation/test 14,223/2,032/4,064; dataset DeepCRISPR.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(CRI-Off)
Configuration: Splice-MS1024Task: BEACON CRI-On: CRISPR on-target efficiency prediction
Dataset subset: DeepCRISPR (BEACON split)
27.59(4.61) Spearman
unitless · higher

Uncertainty: SD 4.61

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON CRI-On: CRISPR on-target efficiency prediction

BEACON harness, fixed downstream head per task. Train/validation/test 1,453/207/416; dataset DeepCRISPR.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(CRI-On)
Configuration: Splice-MS1024Task: BEACON DMP: Distance map prediction
Dataset subset: RNAcontact (BEACON split)
55.89(0.48) R²
unitless · higher

Uncertainty: SD 0.48

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON DMP: Distance map prediction

BEACON harness, fixed downstream head per task. Train/validation/test 188/23/80; dataset RNAcontact.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(DMP)
Configuration: Splice-MS1024Task: BEACON Modif: RNA modification site prediction
Dataset subset: MultiRM (BEACON split)
53.45(6.25) AUROC
unitless · higher

Uncertainty: SD 6.25

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON Modif: RNA modification site prediction

BEACON harness, fixed downstream head per task. Train/validation/test 304,661/3,599/1,200; dataset MultiRM.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(Modif)
Configuration: Splice-MS1024Task: BEACON MRL: Mean ribosome loading prediction
Dataset subset: Optimus (BEACON split)
67.15(30.54) R²
unitless · higher

Uncertainty: SD 30.54

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON MRL: Mean ribosome loading prediction

BEACON harness, fixed downstream head per task. Train/validation/test 76,319/7,600/7,600; dataset Optimus.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(MRL)
Configuration: Splice-MS1024Task: BEACON ncRNA: Non-coding RNA family classification
Dataset subset: Noorul's ncRNA set (BEACON split)
96.05(0.777)% Accuracy
percent · higher

Uncertainty: SD 0.777

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON ncRNA: Non-coding RNA family classification

BEACON harness, fixed downstream head per task. Train/validation/test 5,679/650/2,400; dataset Noorul's ncRNA set.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(ncRNA)
Configuration: Splice-MS1024Task: BEACON PRS: Programmable RNA switch prediction
Dataset subset: Angenent-Mari's switch set (BEACON split)
57.72(0.45) R²
unitless · higher

Uncertainty: SD 0.45

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON PRS: Programmable RNA switch prediction

BEACON harness, fixed downstream head per task. Train/validation/test 73,227/9,153/9,154; dataset Angenent-Mari's switch set.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(PRS)
Configuration: Splice-MS1024Task: BEACON SPL: Splice site prediction
Dataset subset: SpliceAI (BEACON split)
48.52(0.49)% Splice top k accuracy
percent · higher

Uncertainty: SD 0.49

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON SPL: Splice site prediction

BEACON harness, fixed downstream head per task. Train/validation/test 144,628/18,078/16,505; dataset SpliceAI.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(SPL)
Configuration: Splice-MS1024Task: BEACON SSI: Structure score imputation
Dataset subset: StructureImpute (BEACON split)
39.22(0.02) R²
unitless · higher

Uncertainty: SD 0.02

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON SSI: Structure score imputation

BEACON harness, fixed downstream head per task. Train/validation/test 14,049/1,756/3,095; dataset StructureImpute.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(SSI)
Configuration: Splice-MS1024Task: BEACON SSP: Secondary structure prediction
Dataset subset: bpRNA-1m (BEACON split)
68.26(0.20)% F1 (base pairs; binary F1 over all position pairs pooled across the test set; threshold 0.5)
percent · higher

Uncertainty: SD 0.20

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON SSP: Secondary structure prediction

BEACON harness, fixed downstream head per task. Train/validation/test 10,814/1,300/1,305; dataset bpRNA-1m.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(SSP)
Configuration: Splice-MS1024Task: BEACON VDP: Vaccine degradation prediction
Dataset subset: OpenVaccine (BEACON split)
0.313(0.000) Mean columnwise RMSE
unit-unreported · lower

Uncertainty: SD 0.000

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Splice-MS1024 on BEACON VDP: Vaccine degradation prediction

BEACON harness, fixed downstream head per task. Train/validation/test 2,155/245/629; dataset OpenVaccine.

Aggregation: Not reported

BEACON: Benchmark for Comprehensive RNA Tasks and Language Models (arXiv:2406.10391v2) · Table3,p.8,row(Splice-MS1024),column(VDP)

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Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: beacon-model-splice-ms1024

areas
rna-transcriptomes
source locator
Table3,p.8,row(Splice-MS1024)
missing metadata
checkpoint revision: reason: unreported; parameters: reason: unextracted
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