rewirebio.iobenchmarks
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MIMIC v1: Table S11 and Appendix D.3

arXiv preprint · arXiv version 1

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Model or configurationMetricValueDatasetEvaluation
AIDO-RNAAUPRC0.420 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes eCLIP: eCLIP prediction
AIDO-RNAAUPRC0.366 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes GO: GO prediction
AIDO-RNAPearson0.534 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
AIDO-RNAPearson0.360 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
AIDO-RNAAUPRC0.343 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
AIDO-RNAPearson0.555 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
AIDO-RNAAUPRC0.734 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)AIDO-RNA on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
Dilated ResNetAUPRC0.421 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes eCLIP: eCLIP prediction
Dilated ResNetAUPRC0.155 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes GO: GO prediction
Dilated ResNetPearson0.411 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
Dilated ResNetPearson0.448 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
Dilated ResNetAUPRC0.169 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
Dilated ResNetPearson0.647 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
Dilated ResNetAUPRC0.645 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Dilated ResNet on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
DNABERT-SAUPRC0.374 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes eCLIP: eCLIP prediction
DNABERT-SAUPRC0.318 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes GO: GO prediction
DNABERT-SPearson0.393 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
DNABERT-SPearson0.292 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
DNABERT-SAUPRC0.311 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
DNABERT-SPearson0.467 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
DNABERT-SAUPRC0.685 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT-S on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
DNABERT2AUPRC0.371 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes eCLIP: eCLIP prediction
DNABERT2AUPRC0.326 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes GO: GO prediction
DNABERT2Pearson0.534 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
DNABERT2Pearson0.286 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
DNABERT2AUPRC0.325 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
DNABERT2Pearson0.475 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
DNABERT2AUPRC0.675 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)DNABERT2 on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
ERNIE-RNAAUPRC0.373 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes eCLIP: eCLIP prediction
ERNIE-RNAAUPRC0.341 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes GO: GO prediction
ERNIE-RNAPearson0.503 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
ERNIE-RNAPearson0.328 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
ERNIE-RNAAUPRC0.338 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
ERNIE-RNAPearson0.518 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
ERNIE-RNAAUPRC0.691 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)ERNIE-RNA on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
Evo2AUPRC0.473 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes eCLIP: eCLIP prediction
Evo2AUPRC0.467 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes GO: GO prediction
Evo2Pearson0.507 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
Evo2Pearson0.455 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
Evo2AUPRC0.408 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
Evo2Pearson0.661 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
Evo2AUPRC0.767 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)Evo2 on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
HyenaDNAAUPRC0.374 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes eCLIP: eCLIP prediction
HyenaDNAAUPRC0.308 fractionmRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes GO: GO prediction
HyenaDNAPearson0.506 unitlessmRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
HyenaDNAPearson0.287 unitlessmRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
HyenaDNAAUPRC0.311 fractionmRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes Protein Localization: Protein Localization prediction
HyenaDNAPearson0.462 unitlessmRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
HyenaDNAAUPRC0.670 fractionmRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)HyenaDNA on MIMIC mRNABench probes RNA Localization: RNA Localization prediction
MIMICAUPRC0.470 fractionmRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)MIMIC on MIMIC mRNABench probes eCLIP: eCLIP prediction

Claims

Statements this source supports, each with where in the source it was checked.

  • AIDO-RNA: description: Description mRNABench evaluation of mature mRNA embeddings from AIDO.RNA, an RNA foundation model pretrained on 42 million non-coding RNA sequences at single-nucleotide resolution, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-aido-rna: abstract)
  • Dilated ResNet: description: Description Supervised dilated convolutional network baseline, built from three or four DilatedResNet blocks and trained from scratch on each task's training split. (expansion-p3-mrnabench-2025: Appendix A, Overview of Evaluated Models (baselines paragraph); coverage-source-mimic-2026-v1-html: Table S11 and Appendix D.3)
  • DNABERT-S: description: Description mRNABench evaluation of mature mRNA embeddings from DNABERT-S, a genome model built on DNABERT-2 and trained with contrastive objectives to give species-aware DNA embeddings, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-dnabert-s: abstract)
  • DNABERT2: description: Description mRNABench evaluation of mature mRNA embeddings from DNABERT-2, a genome foundation model that tokenises DNA with byte pair encoding instead of k-mers, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-dnabert2: abstract)
  • DNABERT2: uses model discovery-model-dnabert-2: Uses model DNABERT-2 (Table S11, row DNABERT2 [ 33 ]; Appendix D.3)
  • ERNIE-RNA: description: Description mRNABench evaluation of mature mRNA embeddings from ERNIE-RNA, an RNA language model based on a modified BERT with a base-pairing restriction, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-ernie-rna: abstract)
  • Evo2: description: Description mRNABench evaluation of mature mRNA embeddings from Evo 2, a DNA foundation model trained on 9.3 trillion base pairs from all domains of life with a context of up to 1 million nucleotides, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-evo2: abstract)
  • Evo2: uses model discovery-model-evo-2: Uses model Evo 2 (Table S11, row Evo2 [ 29 ]; Appendix D.3)
  • HyenaDNA: description: Description mRNABench evaluation of mature mRNA embeddings from HyenaDNA, a genomic foundation model built on Hyena implicit convolutions and pretrained on the human reference genome with single-nucleotide tokens and contexts of up to 1 million tokens, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-hyenadna: abstract)
  • MIMIC mRNABench probes eCLIP: part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), eCLIP column; Appendix D.3)
  • MIMIC mRNABench probes GO: part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), GO column; Appendix D.3)
  • MIMIC mRNABench probes MRL (LBKWK): part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), MRL (LBKWK) column; Appendix D.3)
  • MIMIC mRNABench probes MRL (Sugimoto): part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), MRL (Sugimoto) column; Appendix D.3)
  • MIMIC mRNABench probes Protein Localization: part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), Protein Localization column; Appendix D.3)
  • MIMIC mRNABench probes RNA Half Life: part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), RNA Half Life column; Appendix D.3)
  • MIMIC mRNABench probes RNA Localization: part of discovery-benchmark-mrnabench: Part of mRNABench (Table S11 (HTML A4.T11), RNA Localization column; Appendix D.3)
  • MIMIC: uses model catalog-model-mimic: Uses model MIMIC (Table S11, row MIMIC; Appendix D.3)
  • NT-v2: description: Description mRNABench evaluation of mature mRNA embeddings from a Nucleotide Transformer model reported as NT-v2, from a family of transformer DNA foundation models (50 million to 2.5 billion parameters, integrating information from 3,202 human genomes and 850 genomes of other species), with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-nt-v2: abstract)
  • NT-v2: uses model discovery-model-nucleotide-transformer: Uses model Nucleotide Transformer (Table S11, row NT-v2 [ 121 ]; Appendix D.3)
  • Orthrus: description: Description mRNABench evaluation of mature mRNA embeddings from Orthrus, a Mamba-based mature RNA foundation model pretrained with a contrastive objective over splice isoforms and orthologous transcripts, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-orthrus: abstract)
  • RiNALMo: description: Description mRNABench evaluation of mature mRNA embeddings from RiNALMo, an RNA language model pretrained on 36 million non-coding RNA sequences, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-rinalmo: abstract)
  • SpliceBERT: description: Description mRNABench evaluation of mature mRNA embeddings from SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, with task scores quoted from prior work in MIMIC Table S11. (coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-splicebert: abstract)

Models, benchmarks and other records

Pipelines (12)

Protocols (7)

Dataset subsets (7)

Evaluations (84)

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