rewirebio.iobenchmarks
Pipeline

SpliceBERT

Embeds mature mRNA with SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, for the mRNABench property prediction tasks.

7 evaluations · 7 results

Overview

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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

7 evaluations · 7 results. Different protocols are not a single leaderboard.

Sorted by AUPRC (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

All 7 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes eCLIP: eCLIP prediction
Dataset subset: mRNABench eCLIP as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.377 AUPRC
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes eCLIP: eCLIP prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 2 (eCLIP)
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes GO: GO prediction
Dataset subset: mRNABench GO as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.382 AUPRC
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes GO: GO prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 3 (GO)
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction
Dataset subset: mRNABench MRL (LBKWK) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.514 Pearson
unitless · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes MRL (LBKWK): MRL (LBKWK) prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 6 (MRL (LBKWK))
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction
Dataset subset: mRNABench MRL (Sugimoto) as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.336 Pearson
unitless · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes MRL (Sugimoto): MRL (Sugimoto) prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 7 (MRL (Sugimoto))
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes Protein Localization: Protein Localization prediction
Dataset subset: mRNABench Protein Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.36 AUPRC
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes Protein Localization: Protein Localization prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 4 (Protein Localization)
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction
Dataset subset: mRNABench RNA Half Life as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.531 Pearson
unitless · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes RNA Half Life: RNA Half Life prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 8 (RNA Half Life)
Pipeline: SpliceBERTProtocol: MIMIC mRNABench probes RNA Localization: RNA Localization prediction
Dataset subset: mRNABench RNA Localization as reported in MIMIC Table S11 (MIMIC mRNABench probes split)
0.726 AUPRC
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Result quoted from another source · Source checked
Methods, coverage and source

SpliceBERT on MIMIC mRNABench probes RNA Localization: RNA Localization prediction

MIMIC uses concatenated register tokens and mean-pooled RNA-track representations with supervised probes. Nucleotide/codon/amino-acid conditioning is selected per task on validation data; predictions are averaged across selected modality subsets. Comparator scores are quoted from prior mRNABench work.

Aggregation: Not reported

MIMIC v1: Table S11 and Appendix D.3 · Table S11 (HTML A4.T11), data row 12 (SpliceBERT [ 77 ]), column 5 (RNA Localization)

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

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Evidence

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Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

3 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Description
Embeds mature mRNA with SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, for the mRNABench property prediction tasks.
Individual claims
MIMIC v1: Table S11 and Appendix D.3

Original source ↗

coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-splicebert: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: arXiv version 1
Retrieved: 2026-09-23

conflicting claim

["automated-source-review","ai-assisted-source-review"] · 2026-10-10

Audit details

Description written from the cited source text; provenance text moved to attributes.source_locator. Independent review 2026-10-10: every stated fact is supported by the cited text.

Conflicting source claim: "mRNABench evaluation of mature mRNA embeddings from SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, with task scores quoted from prior work in MIMIC Table S11.". Claim record status: source_checked.

Field: description

Claim: metadata-correction-51bc8bd036adadd6a826

Source artifact SHA-256: 6408e6fae37567837ca53bd8a1ebef6cf7d3787bbf00dae7556e1b62822ffff0

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Embeds mature mRNA with SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, for the mRNABench property prediction tasks.
Individual claims
mRNABench: A curated benchmark for mature mRNA property and function prediction

Original source ↗

coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-splicebert: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: preprint archived 2025-07-08
Retrieved: 2026-09-16T10:41:16.497221+00:00

conflicting claim

["automated-source-review","ai-assisted-source-review"] · 2026-10-10

Audit details

Description written from the cited source text; provenance text moved to attributes.source_locator. Independent review 2026-10-10: every stated fact is supported by the cited text.

Conflicting source claim: "mRNABench evaluation of mature mRNA embeddings from SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, with task scores quoted from prior work in MIMIC Table S11.". Claim record status: source_checked.

Field: description

Claim: metadata-correction-51bc8bd036adadd6a826

Source artifact SHA-256: 79f6264ee883535203c63a313547e7c57baa85585f76b42f8d899eb17fb7e600

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Description
Embeds mature mRNA with SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, for the mRNABench property prediction tasks.
Individual claims
Abstract: Self-supervised learning on millions of primary RNA sequences from 72 vertebrates improves sequence-based RNA splicing prediction

Original source ↗

coverage-source-mimic-2026-v1-html: Appendix D.3 and Table S11; expansion-p3-mrnabench-2025: abstract; qa-descriptions-20261010-source-splicebert: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Europe PMC core record MED/38605640 (title and abstract), Briefings in bioinformatics 2024
Retrieved: 2026-10-10T06:44:14Z

conflicting claim

["automated-source-review","ai-assisted-source-review"] · 2026-10-10

Audit details

Description written from the cited source text; provenance text moved to attributes.source_locator. Independent review 2026-10-10: every stated fact is supported by the cited text.

Conflicting source claim: "mRNABench evaluation of mature mRNA embeddings from SpliceBERT, a language model pretrained by masked language modelling on primary RNA sequences from 72 vertebrates, with task scores quoted from prior work in MIMIC Table S11.". Claim record status: source_checked.

Field: description

Claim: metadata-correction-51bc8bd036adadd6a826

Source artifact SHA-256: 08d1dce96c933d04a7633bedd5707373ad380029bf833ee20663a6921a773ff1

Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. The response is not byte-stable: on 2026-10-10 a second retrieval of 10 of these 31 records differed only in JSON key order and parsed to identical content. The title and abstractText fields are the evidence.

Inspected artifact

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

3 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: mimic-2026-mrnabench-method-splicebert

areas
rna-transcriptomes
source locator
Table S11, row SpliceBERT [ 77 ]; Appendix D.3; Prior mRNABench evaluated pipeline, quoted in MIMIC Table S11; not a new execution
missing metadata
checkpoint revision: reason: unreported; parameters: reason: unextracted
provenance note
Task scores quoted from prior work in MIMIC Table S11; not a new execution.
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