rewire.itbenchmarks
Dataset subset

hydro

Source-defined subset: hydro. Exact membership and scoring coverage remain as reported in the cited artifact.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

45 evaluations · 89 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: ESM2-650M likelihoodProtocol: FLIP2 hydro low-to-high; held-out test set · hydro
Dataset subset: hydro
0.865 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2-650M likelihood · FLIP2 hydro low-to-high; held-out test set · hydro

FLIP2 hydro low-to-high; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row ESM2-650M likelihood; column ndcg
Configuration: ESMC-300M supervisedProtocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro
Dataset subset: hydro
0.078 ± 0.133 spearman
correlation · higher

Uncertainty: printed spread: 0.133; type: unreported; value: 0.133

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESMC-300M supervised · FLIP2 hydro to-P0A9X9; held-out test set · hydro

FLIP2 hydro to-P0A9X9; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row ESMC-300M supervised; column spearman
Configuration: Ridge (one-hot)Protocol: FLIP2 hydro to-P01053; held-out test set · hydro
Dataset subset: hydro
0.889 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Ridge (one-hot) · FLIP2 hydro to-P01053; held-out test set · hydro

FLIP2 hydro to-P01053; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row Ridge (one-hot); column ndcg
Configuration: ESMC-300M naive supervisedProtocol: FLIP2 hydro to-P06241; held-out test set · hydro
Dataset subset: hydro
0.098 ± 0.024 spearman
correlation · higher

Uncertainty: printed spread: 0.024; type: unreported; value: 0.024

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESMC-300M naive supervised · FLIP2 hydro to-P06241; held-out test set · hydro

FLIP2 hydro to-P06241; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row ESMC-300M naive supervised; column spearman
Configuration: CARP-640M likelihoodProtocol: FLIP2 hydro low-to-high; held-out test set · hydro
Dataset subset: hydro
0.284 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M likelihood · FLIP2 hydro low-to-high; held-out test set · hydro

FLIP2 hydro low-to-high; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row CARP-640M likelihood; column spearman
Configuration: CARP-640M supervisedProtocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro
Dataset subset: hydro
0.961 ± 0.004 ndcg
unitless · higher

Uncertainty: printed spread: 0.004; type: unreported; value: 0.004

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M supervised · FLIP2 hydro to-P0A9X9; held-out test set · hydro

FLIP2 hydro to-P0A9X9; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row CARP-640M supervised; column ndcg
Configuration: Ridge (one-hot)Protocol: FLIP2 hydro to-P06241; held-out test set · hydro
Dataset subset: hydro
−0.138 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Ridge (one-hot) · FLIP2 hydro to-P06241; held-out test set · hydro

FLIP2 hydro to-P06241; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row Ridge (one-hot); column spearman
Configuration: ESM2-650M likelihoodProtocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro
Dataset subset: hydro
0.049 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2-650M likelihood · FLIP2 hydro to-P0A9X9; held-out test set · hydro

FLIP2 hydro to-P0A9X9; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row ESM2-650M likelihood; column spearman
Configuration: CARP-640M naive supervisedProtocol: FLIP2 hydro to-P06241; held-out test set · hydro
Dataset subset: hydro
0.927 ± 0.006 ndcg
unitless · higher

Uncertainty: printed spread: 0.006; type: unreported; value: 0.006

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M naive supervised · FLIP2 hydro to-P06241; held-out test set · hydro

FLIP2 hydro to-P06241; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row CARP-640M naive supervised; column ndcg
Configuration: Ridge (one-hot)Protocol: FLIP2 hydro three-to-many; held-out test set · hydro
Dataset subset: hydro
0.148 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Ridge (one-hot) · FLIP2 hydro three-to-many; held-out test set · hydro

FLIP2 hydro three-to-many; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)Protocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro
Dataset subset: hydro
0.957 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Ridge (one-hot) · FLIP2 hydro to-P0A9X9; held-out test set · hydro

FLIP2 hydro to-P0A9X9; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row Ridge (one-hot); column ndcg
Configuration: ESM2-650M likelihoodProtocol: FLIP2 hydro three-to-many; held-out test set · hydro
Dataset subset: hydro
−0.036 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2-650M likelihood · FLIP2 hydro three-to-many; held-out test set · hydro

FLIP2 hydro three-to-many; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row ESM2-650M likelihood; column spearman
Configuration: CARP-640M supervisedProtocol: FLIP2 hydro three-to-many; held-out test set · hydro
Dataset subset: hydro
0.516 ± 0.035 spearman
correlation · higher

Uncertainty: printed spread: 0.035; type: unreported; value: 0.035

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M supervised · FLIP2 hydro three-to-many; held-out test set · hydro

FLIP2 hydro three-to-many; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row CARP-640M supervised; column spearman
Configuration: CARP-640M likelihoodProtocol: FLIP2 hydro low-to-high; held-out test set · hydro
Dataset subset: hydro
0.921 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M likelihood · FLIP2 hydro low-to-high; held-out test set · hydro

FLIP2 hydro low-to-high; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row CARP-640M likelihood; column ndcg
Configuration: ESMC-300M supervisedProtocol: FLIP2 hydro to-P01053; held-out test set · hydro
Dataset subset: hydro
0.949 ± 0.024 ndcg
unitless · higher

Uncertainty: printed spread: 0.024; type: unreported; value: 0.024

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESMC-300M supervised · FLIP2 hydro to-P01053; held-out test set · hydro

FLIP2 hydro to-P01053; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row ESMC-300M supervised; column ndcg
Configuration: CARP-640M naive supervisedProtocol: FLIP2 hydro to-P01053; held-out test set · hydro
Dataset subset: hydro
0.061 ± 0.094 spearman
correlation · higher

Uncertainty: printed spread: 0.094; type: unreported; value: 0.094

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M naive supervised · FLIP2 hydro to-P01053; held-out test set · hydro

FLIP2 hydro to-P01053; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row CARP-640M naive supervised; column spearman
Configuration: CARP-640M likelihoodProtocol: FLIP2 hydro to-P06241; held-out test set · hydro
Dataset subset: hydro
0.957 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M likelihood · FLIP2 hydro to-P06241; held-out test set · hydro

FLIP2 hydro to-P06241; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row CARP-640M likelihood; column ndcg
Configuration: ESMC-300M naive supervisedProtocol: FLIP2 hydro three-to-many; held-out test set · hydro
Dataset subset: hydro
0.367 ± 0.042 spearman
correlation · higher

Uncertainty: printed spread: 0.042; type: unreported; value: 0.042

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESMC-300M naive supervised · FLIP2 hydro three-to-many; held-out test set · hydro

FLIP2 hydro three-to-many; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row ESMC-300M naive supervised; column spearman
Configuration: CARP-640M supervisedProtocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro
Dataset subset: hydro
0.004 ± 0.103 spearman
correlation · higher

Uncertainty: printed spread: 0.103; type: unreported; value: 0.103

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M supervised · FLIP2 hydro to-P0A9X9; held-out test set · hydro

FLIP2 hydro to-P0A9X9; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row CARP-640M supervised; column spearman
Configuration: ESM2-650M likelihoodProtocol: FLIP2 hydro to-P01053; held-out test set · hydro
Dataset subset: hydro
0.053 spearman
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2-650M likelihood · FLIP2 hydro to-P01053; held-out test set · hydro

FLIP2 hydro to-P01053; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row ESM2-650M likelihood; column spearman
Configuration: Ridge (one-hot)Protocol: FLIP2 hydro three-to-many; held-out test set · hydro
Dataset subset: hydro
0.96 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Ridge (one-hot) · FLIP2 hydro three-to-many; held-out test set · hydro

FLIP2 hydro three-to-many; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row Ridge (one-hot); column ndcg
Configuration: ESMC-300M supervisedProtocol: FLIP2 hydro to-P06241; held-out test set · hydro
Dataset subset: hydro
0.934 ± 0.011 ndcg
unitless · higher

Uncertainty: printed spread: 0.011; type: unreported; value: 0.011

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESMC-300M supervised · FLIP2 hydro to-P06241; held-out test set · hydro

FLIP2 hydro to-P06241; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row ESMC-300M supervised; column ndcg
Configuration: Ridge (one-hot + likelihoods)Protocol: FLIP2 hydro to-P01053; held-out test set · hydro
Dataset subset: hydro
0.942 ndcg
unitless · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Ridge (one-hot + likelihoods) · FLIP2 hydro to-P01053; held-out test set · hydro

FLIP2 hydro to-P01053; held-out test set

Aggregation: reported point estimate

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row Ridge (one-hot + likelihoods); column ndcg
Configuration: CARP-640M supervisedProtocol: FLIP2 hydro to-P01053; held-out test set · hydro
Dataset subset: hydro
0.909 ± 0.008 ndcg
unitless · higher

Uncertainty: printed spread: 0.008; type: unreported; value: 0.008

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CARP-640M supervised · FLIP2 hydro to-P01053; held-out test set · hydro

FLIP2 hydro to-P01053; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row CARP-640M supervised; column ndcg
Configuration: ESMC-300M naive supervisedProtocol: FLIP2 hydro to-P06241; held-out test set · hydro
Dataset subset: hydro
0.927 ± 0.001 ndcg
unitless · higher

Uncertainty: printed spread: 0.001; type: unreported; value: 0.001

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESMC-300M naive supervised · FLIP2 hydro to-P06241; held-out test set · hydro

FLIP2 hydro to-P06241; held-out test set

Aggregation: mean of five random-seed fits (Section 4.3)

FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row ESMC-300M naive supervised; column ndcg

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Subset and evaluation context

This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

3 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
attributes.source_locator
Table A10; row Ridge (one-hot); column spearman
Context-only references
FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications

Original source ↗

Table A10; row Ridge (one-hot); column spearman

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.183348+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: d0e61ca27863c023adddcc225a3e4af1718f2e3fdfe3642bef89c24c93621a17

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

description
Source-defined subset: hydro. Exact membership and scoring coverage remain as reported in the cited artifact.
Context-only references
FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications

Original source ↗

Table A10; row Ridge (one-hot); column spearman

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.183348+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: d0e61ca27863c023adddcc225a3e4af1718f2e3fdfe3642bef89c24c93621a17

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

name
hydro
Context-only references
FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications

Original source ↗

Table A10; row Ridge (one-hot); column spearman

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.183348+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: d0e61ca27863c023adddcc225a3e4af1718f2e3fdfe3642bef89c24c93621a17

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-29-06401fd5b220 · Record review: discovered

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: acquired-dataset-ecef09ad02eca7267357

source locator
Table A10; row Ridge (one-hot); column spearman
missing metadata
split manifest: unextracted
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