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CARP-640M likelihood

Entry in FLIP2, identified only by its entry label; the model or method behind it is not identified.

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Evaluations and results

16 evaluations · 31 results. Different protocols are not a single leaderboard.

Sorted by NDCG (cutoff not stated) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	NDCG (cutoff not stated)	Spearman
CARP-640M likelihoodEvaluation	FLIP2 TrpB one-to-many; held-out test set · TrpB, TrpB	0.992 (best in column)	0.418
CARP-640M likelihoodEvaluation	FLIP2 TrpB two-to-many; held-out test set · TrpB, TrpB	0.992 (best in column)	0.417
CARP-640M likelihoodEvaluation	FLIP2 TrpB by-position; held-out test set · TrpB, TrpB	0.988	0.252
CARP-640M likelihoodEvaluation	FLIP2 hydro to-P0A9X9; held-out test set · hydro, hydro	0.967	−0.032
CARP-640M likelihoodEvaluation	FLIP2 hydro three-to-many; held-out test set · hydro, hydro	0.963	0.165
CARP-640M likelihoodEvaluation	FLIP2 hydro to-P06241; held-out test set · hydro, hydro	0.957	0.393
CARP-640M likelihoodEvaluation	FLIP2 IRED two-to-many; held-out test set · IRED, IRED	0.956	0.144
CARP-640M likelihoodEvaluation	FLIP2 hydro to-P01053; held-out test set · hydro, hydro	0.948	Not reported
CARP-640M likelihoodEvaluation	FLIP2 Amylase close-to-far; held-out test set · Amylase, Amylase	0.945	0.543
CARP-640M likelihoodEvaluation	FLIP2 rhomax by-wild-type; held-out test set · rhomax, rhomax	0.937	0.379
CARP-640M likelihoodEvaluation	FLIP2 Amylase one-to-many; held-out test set · Amylase, Amylase	0.931	0.513
CARP-640M likelihoodEvaluation	FLIP2 hydro low-to-high; held-out test set · hydro, hydro	0.921	0.284
CARP-640M likelihoodEvaluation	FLIP2 Amylase far-to-close; held-out test set · Amylase, Amylase	0.919	0.566 (best in column)
CARP-640M likelihoodEvaluation	FLIP2 Amylase by-mutation; held-out test set · Amylase, Amylase	0.906	0.468
CARP-640M likelihoodEvaluation	FLIP2 NucB two-to-many; held-out test set · NucB, NucB	0.889	0.188
CARP-640M likelihoodEvaluation	FLIP2 PDZ3 single-to-double; held-out test set · PDZ3, PDZ3	0.863	0.043

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Release 2026-11-02-a7f03c9e55a5 · Record review: discovered

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FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Original source · Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256

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Stable ID: acquired-configuration-0549c02d9e97ac8ae9a3

source locator: Table A1; row CARP-640M likelihood; column spearman
reported configuration: CARP-640M likelihood
missing metadata: checkpoint revision: reason: unreported; model family: reason: unextracted
provenance note: Exact source-reported configuration or submission label. Family membership, checkpoint identity and aliases have not been inferred.

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Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase far-to-close; held-out test set · Amylase Dataset subset: Amylase	0.919 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase far-to-close; held-out test set · Amylase FLIP2 Amylase far-to-close; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A3; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 IRED two-to-many; held-out test set · IRED Dataset subset: IRED	0.144 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 IRED two-to-many; held-out test set · IRED FLIP2 IRED two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A5; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 hydro low-to-high; held-out test set · hydro Dataset subset: hydro	0.284 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 hydro low-to-high; held-out test set · hydro FLIP2 hydro low-to-high; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase far-to-close; held-out test set · Amylase Dataset subset: Amylase	0.566 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase far-to-close; held-out test set · Amylase FLIP2 Amylase far-to-close; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A3; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 hydro low-to-high; held-out test set · hydro Dataset subset: hydro	0.921 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 hydro low-to-high; held-out test set · hydro FLIP2 hydro low-to-high; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 NucB two-to-many; held-out test set · NucB Dataset subset: NucB	0.188 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 NucB two-to-many; held-out test set · NucB FLIP2 NucB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A6; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 hydro to-P06241; held-out test set · hydro Dataset subset: hydro	0.957 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 hydro to-P06241; held-out test set · hydro FLIP2 hydro to-P06241; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase by-mutation; held-out test set · Amylase Dataset subset: Amylase	0.468 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase by-mutation; held-out test set · Amylase FLIP2 Amylase by-mutation; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A4; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 Dataset subset: PDZ3	0.863 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 FLIP2 PDZ3 single-to-double; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A16; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 rhomax by-wild-type; held-out test set · rhomax Dataset subset: rhomax	0.937 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 rhomax by-wild-type; held-out test set · rhomax FLIP2 rhomax by-wild-type; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A15; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase one-to-many; held-out test set · Amylase Dataset subset: Amylase	0.931 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase one-to-many; held-out test set · Amylase FLIP2 Amylase one-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A1; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 TrpB one-to-many; held-out test set · TrpB Dataset subset: TrpB	0.418 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 TrpB one-to-many; held-out test set · TrpB FLIP2 TrpB one-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A7; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 TrpB two-to-many; held-out test set · TrpB Dataset subset: TrpB	0.992 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 TrpB two-to-many; held-out test set · TrpB FLIP2 TrpB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A8; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro Dataset subset: hydro	−0.032 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 hydro to-P0A9X9; held-out test set · hydro FLIP2 hydro to-P0A9X9; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase by-mutation; held-out test set · Amylase Dataset subset: Amylase	0.906 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase by-mutation; held-out test set · Amylase FLIP2 Amylase by-mutation; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A4; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase close-to-far; held-out test set · Amylase Dataset subset: Amylase	0.543 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase close-to-far; held-out test set · Amylase FLIP2 Amylase close-to-far; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A2; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 TrpB one-to-many; held-out test set · TrpB Dataset subset: TrpB	0.992 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 TrpB one-to-many; held-out test set · TrpB FLIP2 TrpB one-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A7; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 TrpB by-position; held-out test set · TrpB Dataset subset: TrpB	0.988 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 TrpB by-position; held-out test set · TrpB FLIP2 TrpB by-position; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A9; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 hydro to-P06241; held-out test set · hydro Dataset subset: hydro	0.393 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 hydro to-P06241; held-out test set · hydro FLIP2 hydro to-P06241; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 Amylase one-to-many; held-out test set · Amylase Dataset subset: Amylase	0.513 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 Amylase one-to-many; held-out test set · Amylase FLIP2 Amylase one-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A1; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 Dataset subset: PDZ3	0.043 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 FLIP2 PDZ3 single-to-double; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A16; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 TrpB two-to-many; held-out test set · TrpB Dataset subset: TrpB	0.417 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 TrpB two-to-many; held-out test set · TrpB FLIP2 TrpB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A8; row CARP-640M likelihood; column spearman
Configuration: CARP-640M likelihood	Protocol: FLIP2 hydro to-P01053; held-out test set · hydro Dataset subset: hydro	0.948 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 hydro to-P01053; held-out test set · hydro FLIP2 hydro to-P01053; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 IRED two-to-many; held-out test set · IRED Dataset subset: IRED	0.956 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 IRED two-to-many; held-out test set · IRED FLIP2 IRED two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A5; row CARP-640M likelihood; column ndcg
Configuration: CARP-640M likelihood	Protocol: FLIP2 NucB two-to-many; held-out test set · NucB Dataset subset: NucB	0.889 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M likelihood · FLIP2 NucB two-to-many; held-out test set · NucB FLIP2 NucB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A6; row CARP-640M likelihood; column ndcg