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CARP-640M supervised

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16 evaluations · 30 results

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16 evaluations · 30 results. Different protocols are not a single leaderboard.

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FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Original source · Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256

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source locator: Table A1; row CARP-640M supervised; column spearman
reported configuration: CARP-640M supervised
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Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro Dataset subset: hydro	0.961 ± 0.004 ndcg unitless · higher Uncertainty: printed spread: 0.004; type: unreported; value: 0.004 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro to-P0A9X9; held-out test set · hydro FLIP2 hydro to-P0A9X9; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 Amylase by-mutation; held-out test set · Amylase Dataset subset: Amylase	0.926 ± 0.050 ndcg unitless · higher Uncertainty: printed spread: 0.050; type: unreported; value: 0.05 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 Amylase by-mutation; held-out test set · Amylase FLIP2 Amylase by-mutation; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A4; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro three-to-many; held-out test set · hydro Dataset subset: hydro	0.516 ± 0.035 spearman correlation · higher Uncertainty: printed spread: 0.035; type: unreported; value: 0.035 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro three-to-many; held-out test set · hydro FLIP2 hydro three-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 Amylase by-mutation; held-out test set · Amylase Dataset subset: Amylase	0.551 ± 0.239 spearman correlation · higher Uncertainty: printed spread: 0.239; type: unreported; value: 0.239 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 Amylase by-mutation; held-out test set · Amylase FLIP2 Amylase by-mutation; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A4; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 TrpB two-to-many; held-out test set · TrpB Dataset subset: TrpB	0.996 ± 0.000 ndcg unitless · higher Uncertainty: printed spread: 0.000; type: unreported; value: 0 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 TrpB two-to-many; held-out test set · TrpB FLIP2 TrpB two-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A8; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro Dataset subset: hydro	0.004 ± 0.103 spearman correlation · higher Uncertainty: printed spread: 0.103; type: unreported; value: 0.103 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro to-P0A9X9; held-out test set · hydro FLIP2 hydro to-P0A9X9; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 Amylase one-to-many; held-out test set · Amylase Dataset subset: Amylase	0.873 ± 0.029 ndcg unitless · higher Uncertainty: printed spread: 0.029; type: unreported; value: 0.029 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 Amylase one-to-many; held-out test set · Amylase FLIP2 Amylase one-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A1; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 Amylase far-to-close; held-out test set · Amylase Dataset subset: Amylase	0.140 ± 0.102 spearman correlation · higher Uncertainty: printed spread: 0.102; type: unreported; value: 0.102 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 Amylase far-to-close; held-out test set · Amylase FLIP2 Amylase far-to-close; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A3; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro to-P01053; held-out test set · hydro Dataset subset: hydro	0.909 ± 0.008 ndcg unitless · higher Uncertainty: printed spread: 0.008; type: unreported; value: 0.008 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro to-P01053; held-out test set · hydro FLIP2 hydro to-P01053; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 TrpB by-position; held-out test set · TrpB Dataset subset: TrpB	0.983 ± 0.003 ndcg unitless · higher Uncertainty: printed spread: 0.003; type: unreported; value: 0.003 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 TrpB by-position; held-out test set · TrpB FLIP2 TrpB by-position; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A9; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro low-to-high; held-out test set · hydro Dataset subset: hydro	0.188 ± 0.071 spearman correlation · higher Uncertainty: printed spread: 0.071; type: unreported; value: 0.071 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro low-to-high; held-out test set · hydro FLIP2 hydro low-to-high; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 Amylase close-to-far; held-out test set · Amylase Dataset subset: Amylase	0.081 ± 0.055 spearman correlation · higher Uncertainty: printed spread: 0.055; type: unreported; value: 0.055 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 Amylase close-to-far; held-out test set · Amylase FLIP2 Amylase close-to-far; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A2; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro to-P06241; held-out test set · hydro Dataset subset: hydro	0.933 ± 0.008 ndcg unitless · higher Uncertainty: printed spread: 0.008; type: unreported; value: 0.008 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro to-P06241; held-out test set · hydro FLIP2 hydro to-P06241; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 IRED two-to-many; held-out test set · IRED Dataset subset: IRED	0.948 ± 0.004 ndcg unitless · higher Uncertainty: printed spread: 0.004; type: unreported; value: 0.004 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 IRED two-to-many; held-out test set · IRED FLIP2 IRED two-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A5; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 Amylase far-to-close; held-out test set · Amylase Dataset subset: Amylase	0.832 ± 0.019 ndcg unitless · higher Uncertainty: printed spread: 0.019; type: unreported; value: 0.019 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 Amylase far-to-close; held-out test set · Amylase FLIP2 Amylase far-to-close; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A3; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 TrpB two-to-many; held-out test set · TrpB Dataset subset: TrpB	0.509 ± 0.010 spearman correlation · higher Uncertainty: printed spread: 0.010; type: unreported; value: 0.01 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 TrpB two-to-many; held-out test set · TrpB FLIP2 TrpB two-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A8; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro low-to-high; held-out test set · hydro Dataset subset: hydro	0.887 ± 0.007 ndcg unitless · higher Uncertainty: printed spread: 0.007; type: unreported; value: 0.007 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro low-to-high; held-out test set · hydro FLIP2 hydro low-to-high; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 Dataset subset: PDZ3	0.882 ± 0.015 ndcg unitless · higher Uncertainty: printed spread: 0.015; type: unreported; value: 0.015 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 FLIP2 PDZ3 single-to-double; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A16; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro to-P01053; held-out test set · hydro Dataset subset: hydro	0.049 ± 0.088 spearman correlation · higher Uncertainty: printed spread: 0.088; type: unreported; value: 0.088 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro to-P01053; held-out test set · hydro FLIP2 hydro to-P01053; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 TrpB one-to-many; held-out test set · TrpB Dataset subset: TrpB	0.992 ± 0.002 ndcg unitless · higher Uncertainty: printed spread: 0.002; type: unreported; value: 0.002 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 TrpB one-to-many; held-out test set · TrpB FLIP2 TrpB one-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A7; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 NucB two-to-many; held-out test set · NucB Dataset subset: NucB	0.970 ± 0.001 ndcg unitless · higher Uncertainty: printed spread: 0.001; type: unreported; value: 0.001 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 NucB two-to-many; held-out test set · NucB FLIP2 NucB two-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A6; row CARP-640M supervised; column ndcg
Configuration: CARP-640M supervised	Protocol: FLIP2 TrpB by-position; held-out test set · TrpB Dataset subset: TrpB	0.167 ± 0.018 spearman correlation · higher Uncertainty: printed spread: 0.018; type: unreported; value: 0.018 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 TrpB by-position; held-out test set · TrpB FLIP2 TrpB by-position; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A9; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 NucB two-to-many; held-out test set · NucB Dataset subset: NucB	0.717 ± 0.012 spearman correlation · higher Uncertainty: printed spread: 0.012; type: unreported; value: 0.012 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 NucB two-to-many; held-out test set · NucB FLIP2 NucB two-to-many; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A6; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 hydro to-P06241; held-out test set · hydro Dataset subset: hydro	0.150 ± 0.046 spearman correlation · higher Uncertainty: printed spread: 0.046; type: unreported; value: 0.046 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 hydro to-P06241; held-out test set · hydro FLIP2 hydro to-P06241; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row CARP-640M supervised; column spearman
Configuration: CARP-640M supervised	Protocol: FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 Dataset subset: PDZ3	0.512 ± 0.014 spearman correlation · higher Uncertainty: printed spread: 0.014; type: unreported; value: 0.014 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source CARP-640M supervised · FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 FLIP2 PDZ3 single-to-double; held-out test set Aggregation: mean of five random-seed fits (Section 4.3) FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A16; row CARP-640M supervised; column spearman