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Ridge (one-hot)

Entry in FLIP2, identified only by its entry label; the model or method behind it is not identified.

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Evaluations and results

16 evaluations · 31 results. Different protocols are not a single leaderboard.

Sorted by NDCG (cutoff not stated) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	NDCG (cutoff not stated)	Spearman
Ridge (one-hot)Evaluation	FLIP2 TrpB two-to-many; held-out test set · TrpB, TrpB	0.994 (best in column)	0.437
Ridge (one-hot)Evaluation	FLIP2 TrpB one-to-many; held-out test set · TrpB, TrpB	0.989	0.441
Ridge (one-hot)Evaluation	FLIP2 TrpB by-position; held-out test set · TrpB, TrpB	0.987	0.274
Ridge (one-hot)Evaluation	FLIP2 hydro three-to-many; held-out test set · hydro, hydro	0.96	0.148
Ridge (one-hot)Evaluation	FLIP2 IRED two-to-many; held-out test set · IRED, IRED	0.96	0.193
Ridge (one-hot)Evaluation	FLIP2 hydro to-P0A9X9; held-out test set · hydro, hydro	0.957	−0.170
Ridge (one-hot)Evaluation	FLIP2 NucB two-to-many; held-out test set · NucB, NucB	0.943	0.606
Ridge (one-hot)Evaluation	FLIP2 Amylase by-mutation; held-out test set · Amylase, Amylase	0.94	0.648 (best in column)
Ridge (one-hot)Evaluation	FLIP2 rhomax by-wild-type; held-out test set · rhomax, rhomax	0.939	0.327
Ridge (one-hot)Evaluation	FLIP2 hydro to-P06241; held-out test set · hydro, hydro	0.913	−0.138
Ridge (one-hot)Evaluation	FLIP2 Amylase one-to-many; held-out test set · Amylase, Amylase	0.903	0.43
Ridge (one-hot)Evaluation	FLIP2 hydro to-P01053; held-out test set · hydro, hydro	0.889	−0.204
Ridge (one-hot)Evaluation	FLIP2 hydro low-to-high; held-out test set · hydro, hydro	0.887	0.146
Ridge (one-hot)Evaluation	FLIP2 PDZ3 single-to-double; held-out test set · PDZ3, PDZ3	0.873	0.476
Ridge (one-hot)Evaluation	FLIP2 Amylase close-to-far; held-out test set · Amylase, Amylase	0.865	Not reported
Ridge (one-hot)Evaluation	FLIP2 Amylase far-to-close; held-out test set · Amylase, Amylase	0.836	0.036

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Release 2026-11-02-a7f03c9e55a5 · Record review: discovered

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FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Original source · Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256

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Stable ID: acquired-configuration-d941431a8e4de18380f5

source locator: Table A1; row Ridge (one-hot); column spearman
reported configuration: Ridge (one-hot)
missing metadata: checkpoint revision: reason: unreported; model family: reason: unextracted
provenance note: Exact source-reported configuration or submission label. Family membership, checkpoint identity and aliases have not been inferred.

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Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro to-P01053; held-out test set · hydro Dataset subset: hydro	0.889 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro to-P01053; held-out test set · hydro FLIP2 hydro to-P01053; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 Amylase close-to-far; held-out test set · Amylase Dataset subset: Amylase	0.865 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 Amylase close-to-far; held-out test set · Amylase FLIP2 Amylase close-to-far; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A2; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro to-P06241; held-out test set · hydro Dataset subset: hydro	−0.138 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro to-P06241; held-out test set · hydro FLIP2 hydro to-P06241; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro three-to-many; held-out test set · hydro Dataset subset: hydro	0.148 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro three-to-many; held-out test set · hydro FLIP2 hydro three-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro to-P0A9X9; held-out test set · hydro Dataset subset: hydro	0.957 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro to-P0A9X9; held-out test set · hydro FLIP2 hydro to-P0A9X9; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A13; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 rhomax by-wild-type; held-out test set · rhomax Dataset subset: rhomax	0.939 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 rhomax by-wild-type; held-out test set · rhomax FLIP2 rhomax by-wild-type; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A15; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro three-to-many; held-out test set · hydro Dataset subset: hydro	0.96 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro three-to-many; held-out test set · hydro FLIP2 hydro three-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A10; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro to-P06241; held-out test set · hydro Dataset subset: hydro	0.913 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro to-P06241; held-out test set · hydro FLIP2 hydro to-P06241; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A12; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 Dataset subset: PDZ3	0.873 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 FLIP2 PDZ3 single-to-double; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A16; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 IRED two-to-many; held-out test set · IRED Dataset subset: IRED	0.193 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 IRED two-to-many; held-out test set · IRED FLIP2 IRED two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A5; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro to-P01053; held-out test set · hydro Dataset subset: hydro	−0.204 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro to-P01053; held-out test set · hydro FLIP2 hydro to-P01053; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A14; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 IRED two-to-many; held-out test set · IRED Dataset subset: IRED	0.96 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 IRED two-to-many; held-out test set · IRED FLIP2 IRED two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A5; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 NucB two-to-many; held-out test set · NucB Dataset subset: NucB	0.606 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 NucB two-to-many; held-out test set · NucB FLIP2 NucB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A6; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 Amylase by-mutation; held-out test set · Amylase Dataset subset: Amylase	0.94 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 Amylase by-mutation; held-out test set · Amylase FLIP2 Amylase by-mutation; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A4; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 Amylase one-to-many; held-out test set · Amylase Dataset subset: Amylase	0.903 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 Amylase one-to-many; held-out test set · Amylase FLIP2 Amylase one-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A1; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro low-to-high; held-out test set · hydro Dataset subset: hydro	0.887 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro low-to-high; held-out test set · hydro FLIP2 hydro low-to-high; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 Amylase one-to-many; held-out test set · Amylase Dataset subset: Amylase	0.43 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 Amylase one-to-many; held-out test set · Amylase FLIP2 Amylase one-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A1; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 rhomax by-wild-type; held-out test set · rhomax Dataset subset: rhomax	0.327 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 rhomax by-wild-type; held-out test set · rhomax FLIP2 rhomax by-wild-type; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A15; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 Amylase far-to-close; held-out test set · Amylase Dataset subset: Amylase	0.036 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 Amylase far-to-close; held-out test set · Amylase FLIP2 Amylase far-to-close; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A3; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 hydro low-to-high; held-out test set · hydro Dataset subset: hydro	0.146 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 hydro low-to-high; held-out test set · hydro FLIP2 hydro low-to-high; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A11; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 TrpB by-position; held-out test set · TrpB Dataset subset: TrpB	0.274 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 TrpB by-position; held-out test set · TrpB FLIP2 TrpB by-position; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A9; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 NucB two-to-many; held-out test set · NucB Dataset subset: NucB	0.943 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 NucB two-to-many; held-out test set · NucB FLIP2 NucB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A6; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 Dataset subset: PDZ3	0.476 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 PDZ3 single-to-double; held-out test set · PDZ3 FLIP2 PDZ3 single-to-double; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A16; row Ridge (one-hot); column spearman
Configuration: Ridge (one-hot)	Protocol: FLIP2 TrpB two-to-many; held-out test set · TrpB Dataset subset: TrpB	0.994 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 TrpB two-to-many; held-out test set · TrpB FLIP2 TrpB two-to-many; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A8; row Ridge (one-hot); column ndcg
Configuration: Ridge (one-hot)	Protocol: FLIP2 Amylase far-to-close; held-out test set · Amylase Dataset subset: Amylase	0.836 NDCG (cutoff not stated) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Ridge (one-hot) · FLIP2 Amylase far-to-close; held-out test set · Amylase FLIP2 Amylase far-to-close; held-out test set Aggregation: reported point estimate FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications · Table A3; row Ridge (one-hot); column ndcg