Dataset

GUANinE gpra-c test set

Yeast promoter expression (GPRA), complex library.

Evaluation results

31 evaluations · 31 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: 5-mer kNN (fine-tuned, GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	58.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source 5-mer kNN on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row '5-mer kNN', column 'gpra-c' (ρ)
Configuration: 5-mer LinSVR (fine-tuned, GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	69.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source 5-mer LinSVR on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row '5-mer LinSVR', column 'gpra-c' (ρ)
Configuration: AIDO.DNA_300m (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	73.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source AIDO.DNA_300m on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'AIDO.DNA_300m', column 'gpra-c' (ρ)
Configuration: Borzoi (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	71.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Borzoi on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Borzoi', column 'gpra-c' (ρ)
Configuration: Caduceus-PS (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	72.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Caduceus-PS on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Caduceus-PS', column 'gpra-c' (ρ)
Configuration: ChromBPNet-ATAC-F0 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	71.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source ChromBPNet-ATAC-F0 on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ChromBPNet-ATAC-F0', column 'gpra-c' (ρ)
Configuration: ChromBPNet-ATAC-F3 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	70.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source ChromBPNet-ATAC-F3 on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ChromBPNet-ATAC-F3', column 'gpra-c' (ρ)
Configuration: DeepSEA (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	68.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source DeepSEA on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'DeepSEA', column 'gpra-c' (ρ)
Configuration: DNABERT-2 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	69.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source DNABERT-2 on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'DNABERT-2', column 'gpra-c' (ρ)
Configuration: Enformer (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	70.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Enformer on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enformer', column 'gpra-c' (ρ)
Configuration: Enformer (Pre-output) (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	70.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Enformer (Pre-output) on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enformer (Pre-output)', column 'gpra-c' (ρ)
Configuration: Enigma-Distilled (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	68 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Enigma-Distilled on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enigma-Distilled', column 'gpra-c' (ρ)
Configuration: ESA-dna2vec (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	59.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source ESA-dna2vec on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ESA-dna2vec', column 'gpra-c' (ρ)
Configuration: Evo2_1B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	72.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Evo2_1B_base on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_1B_base', column 'gpra-c' (ρ)
Configuration: Evo2_7B (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	† Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Evo2_7B on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_7B', column 'gpra-c' (ρ)
Configuration: Evo2_7B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	75.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Evo2_7B_base on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_7B_base', column 'gpra-c' (ρ)
Configuration: GC-content (zero-shot, GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	53 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source GC-content on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GC-content', column 'gpra-c' (ρ)
Configuration: GENA-LM-bert-base-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	71.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source GENA-LM-bert-base-t2t on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-base-t2t', column 'gpra-c' (ρ)
Configuration: GENA-LM-bert-base-t2t-enf (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	70.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source GENA-LM-bert-base-t2t-enf on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-base-t2t-enf', column 'gpra-c' (ρ)
Configuration: GENA-LM-bert-large-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	71.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source GENA-LM-bert-large-t2t on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-large-t2t', column 'gpra-c' (ρ)
Configuration: GENA-LM-bigbird-base-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	71.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source GENA-LM-bigbird-base-t2t on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bigbird-base-t2t', column 'gpra-c' (ρ)
Configuration: hgT5-8195 (fine-tuned, GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	84.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source hgT5-8195 on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'hgT5-8195', column 'gpra-c' (ρ)
Configuration: Mistral-DNA-422m-hg38 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	69.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Mistral-DNA-422m-hg38 on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Mistral-DNA-422m-hg38', column 'gpra-c' (ρ)
Configuration: NTv2-100m (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	71.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NTv2-100m on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'NTv2-100m', column 'gpra-c' (ρ)
Configuration: NTv2-500m (1% eval (evaluated with 1% of the training set), GUANinE v1.1)	Protocol: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2) Dataset: GUANinE gpra-c test set	72.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NTv2-500m on GUANinE gpra-c lit-genomics-20261011-guanine-protocol-gpra-c Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'NTv2-500m', column 'gpra-c' (ρ)

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Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Source location Table 2 column header Context-only references	GUANinE v1.1 reveals complementarity of supervised and genomic language models Original source ↗ Table 2 column header Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML Retrieved: 2026-10-11T00:40:24Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Split Test set Context-only references	GUANinE v1.1 reveals complementarity of supervised and genomic language models Original source ↗ Table 2 column header Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML Retrieved: 2026-10-11T00:40:24Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.split` Source artifact SHA-256: `f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Version GUANinE v1.1 Context-only references	GUANinE v1.1 reveals complementarity of supervised and genomic language models Original source ↗ Table 2 column header Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML Retrieved: 2026-10-11T00:40:24Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.version` Source artifact SHA-256: `f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Description Yeast promoter expression (GPRA), complex library. Context-only references	GUANinE v1.1 reveals complementarity of supervised and genomic language models Original source ↗ Table 2 column header Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML Retrieved: 2026-10-11T00:40:24Z	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Name GUANinE gpra-c test set Context-only references	GUANinE v1.1 reveals complementarity of supervised and genomic language models Original source ↗ Table 2 column header Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML Retrieved: 2026-10-11T00:40:24Z	not individually reviewed No individual claim review recorded Audit details Field: `name` Source artifact SHA-256: `f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

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GUANinE v1.1 reveals complementarity of supervised and genomic language models · Original source · Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML

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Technical metadata and extraction receipts

Stable ID: lit-genomics-20261011-guanine-data-gpra-c

areas: dna-genomes
contexts: research
version: GUANinE v1.1
split: Test set
source locator: Table 2 column header

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uses data: GUANinE v1.1 gpra-c, Spearman rho x100 (Table 2)

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