| Configuration: 5-mer kNN (fine-tuned, GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 44.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source5-mer kNN on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row '5-mer kNN', column 'cons100' (ρ) |
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| Configuration: 5-mer LinSVR (fine-tuned, GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 45 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and source5-mer LinSVR on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row '5-mer LinSVR', column 'cons100' (ρ) |
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| Configuration: AIDO.DNA_300m (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 51.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceAIDO.DNA_300m on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'AIDO.DNA_300m', column 'cons100' (ρ) |
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| Configuration: Borzoi (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 59.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBorzoi on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Borzoi', column 'cons100' (ρ) |
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| Configuration: Caduceus-PS (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 62.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCaduceus-PS on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Caduceus-PS', column 'cons100' (ρ) |
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| Configuration: ChromBPNet-ATAC-F0 (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 41.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceChromBPNet-ATAC-F0 on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ChromBPNet-ATAC-F0', column 'cons100' (ρ) |
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| Configuration: ChromBPNet-ATAC-F3 (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 40.3 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceChromBPNet-ATAC-F3 on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ChromBPNet-ATAC-F3', column 'cons100' (ρ) |
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| Configuration: DeepSEA (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 43.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceDeepSEA on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'DeepSEA', column 'cons100' (ρ) |
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| Configuration: DNABERT-2 (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 50.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceDNABERT-2 on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'DNABERT-2', column 'cons100' (ρ) |
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| Configuration: ENCFF180XQC (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 6.46 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceENCFF180XQC on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ENCFF180XQC', column 'cons100' (ρ) |
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| Configuration: Enformer (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 62.2 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEnformer on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enformer', column 'cons100' (ρ) |
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| Configuration: Enformer (Pre-output) (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 62.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEnformer (Pre-output) on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enformer (Pre-output)', column 'cons100' (ρ) |
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| Configuration: Enigma-Distilled (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 45.8 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEnigma-Distilled on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enigma-Distilled', column 'cons100' (ρ) |
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| Configuration: ESA-dna2vec (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 39.8 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceESA-dna2vec on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ESA-dna2vec', column 'cons100' (ρ) |
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| Configuration: Evo2_1B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 55.2 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEvo2_1B_base on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_1B_base', column 'cons100' (ρ) |
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| Configuration: Evo2_7B (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 65.3 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEvo2_7B on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_7B', column 'cons100' (ρ) |
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| Configuration: Evo2_7B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 61.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEvo2_7B_base on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_7B_base', column 'cons100' (ρ) |
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| Configuration: GC-content (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 39.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceGC-content on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GC-content', column 'cons100' (ρ) |
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| Configuration: GENA-LM-bert-base-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 56 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM-bert-base-t2t on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-base-t2t', column 'cons100' (ρ) |
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| Configuration: GENA-LM-bert-base-t2t-enf (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 56.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM-bert-base-t2t-enf on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-base-t2t-enf', column 'cons100' (ρ) |
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| Configuration: GENA-LM-bert-large-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 59.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM-bert-large-t2t on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-large-t2t', column 'cons100' (ρ) |
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| Configuration: GENA-LM-bigbird-base-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 61.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGENA-LM-bigbird-base-t2t on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bigbird-base-t2t', column 'cons100' (ρ) |
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| Configuration: hgT5-8195 (fine-tuned, GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 46.2 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcehgT5-8195 on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'hgT5-8195', column 'cons100' (ρ) |
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| Configuration: Mistral-DNA-422m-hg38 (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 50.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceMistral-DNA-422m-hg38 on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Mistral-DNA-422m-hg38', column 'cons100' (ρ) |
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| Configuration: NTv2-100m (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2) Dataset: GUANinE cons100 test set | 57.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNTv2-100m on GUANinE cons100 lit-genomics-20261011-guanine-protocol-cons100 Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'NTv2-100m', column 'cons100' (ρ) |
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