rewirebio.iobenchmarks
Dataset

GUANinE cons100 test set

Sequence conservation, 100-way.

Evaluation results

32 evaluations · 32 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: 5-mer kNN (fine-tuned, GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
44.5 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

5-mer kNN on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row '5-mer kNN', column 'cons100' (ρ)
Configuration: 5-mer LinSVR (fine-tuned, GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
45 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

5-mer LinSVR on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row '5-mer LinSVR', column 'cons100' (ρ)
Configuration: AIDO.DNA_300m (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
51.5 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.DNA_300m on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'AIDO.DNA_300m', column 'cons100' (ρ)
Configuration: Borzoi (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
59.7 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Borzoi on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Borzoi', column 'cons100' (ρ)
Configuration: Caduceus-PS (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
62.4 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Caduceus-PS on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Caduceus-PS', column 'cons100' (ρ)
Configuration: ChromBPNet-ATAC-F0 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
41.5 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ChromBPNet-ATAC-F0 on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ChromBPNet-ATAC-F0', column 'cons100' (ρ)
Configuration: ChromBPNet-ATAC-F3 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
40.3 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ChromBPNet-ATAC-F3 on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ChromBPNet-ATAC-F3', column 'cons100' (ρ)
Configuration: DeepSEA (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
43.4 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DeepSEA on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'DeepSEA', column 'cons100' (ρ)
Configuration: DNABERT-2 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
50.4 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT-2 on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'DNABERT-2', column 'cons100' (ρ)
Configuration: ENCFF180XQC (zero-shot, GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
6.46 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ENCFF180XQC on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ENCFF180XQC', column 'cons100' (ρ)
Configuration: Enformer (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
62.2 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Enformer on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enformer', column 'cons100' (ρ)
Configuration: Enformer (Pre-output) (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
62.4 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Enformer (Pre-output) on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enformer (Pre-output)', column 'cons100' (ρ)
Configuration: Enigma-Distilled (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
45.8 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Enigma-Distilled on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Enigma-Distilled', column 'cons100' (ρ)
Configuration: ESA-dna2vec (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
39.8 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

ESA-dna2vec on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'ESA-dna2vec', column 'cons100' (ρ)
Configuration: Evo2_1B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
55.2 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo2_1B_base on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_1B_base', column 'cons100' (ρ)
Configuration: Evo2_7B (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
65.3 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo2_7B on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_7B', column 'cons100' (ρ)
Configuration: Evo2_7B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
61.9 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo2_7B_base on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Evo2_7B_base', column 'cons100' (ρ)
Configuration: GC-content (zero-shot, GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
39.6 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GC-content on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GC-content', column 'cons100' (ρ)
Configuration: GENA-LM-bert-base-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
56 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GENA-LM-bert-base-t2t on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-base-t2t', column 'cons100' (ρ)
Configuration: GENA-LM-bert-base-t2t-enf (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
56.5 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GENA-LM-bert-base-t2t-enf on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-base-t2t-enf', column 'cons100' (ρ)
Configuration: GENA-LM-bert-large-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
59.9 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GENA-LM-bert-large-t2t on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bert-large-t2t', column 'cons100' (ρ)
Configuration: GENA-LM-bigbird-base-t2t (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
61.5 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GENA-LM-bigbird-base-t2t on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'GENA-LM-bigbird-base-t2t', column 'cons100' (ρ)
Configuration: hgT5-8195 (fine-tuned, GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
46.2 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

hgT5-8195 on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'hgT5-8195', column 'cons100' (ρ)
Configuration: Mistral-DNA-422m-hg38 (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
50.7 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Mistral-DNA-422m-hg38 on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'Mistral-DNA-422m-hg38', column 'cons100' (ρ)
Configuration: NTv2-100m (1% eval (evaluated with 1% of the training set), GUANinE v1.1)Protocol: GUANinE v1.1 cons100, Spearman rho x100 (Table 2)
Dataset: GUANinE cons100 test set
57.9 Spearman (GUANinE v1.1 test set)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NTv2-100m on GUANinE cons100

lit-genomics-20261011-guanine-protocol-cons100

Aggregation: Not reported

GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 2, row 'NTv2-100m', column 'cons100' (ρ)

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
  • Compute requirements are estimated: not yet verified

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

5 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Source location
Table 2 column header
Context-only references
GUANinE v1.1 reveals complementarity of supervised and genomic language models

Original source ↗

Table 2 column header

Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML
Retrieved: 2026-10-11T00:40:24Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Split
Test set
Context-only references
GUANinE v1.1 reveals complementarity of supervised and genomic language models

Original source ↗

Table 2 column header

Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML
Retrieved: 2026-10-11T00:40:24Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.split

Source artifact SHA-256: f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Version
GUANinE v1.1
Context-only references
GUANinE v1.1 reveals complementarity of supervised and genomic language models

Original source ↗

Table 2 column header

Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML
Retrieved: 2026-10-11T00:40:24Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.version

Source artifact SHA-256: f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Sequence conservation, 100-way.
Context-only references
GUANinE v1.1 reveals complementarity of supervised and genomic language models

Original source ↗

Table 2 column header

Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML
Retrieved: 2026-10-11T00:40:24Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
GUANinE cons100 test set
Context-only references
GUANinE v1.1 reveals complementarity of supervised and genomic language models

Original source ↗

Table 2 column header

Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML
Retrieved: 2026-10-11T00:40:24Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: f6cc4294a1519fb5579eebb29ffd919afad0198a3bf8b751635d73b17b33ef79

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: lit-genomics-20261011-guanine-data-cons100

areas
dna-genomes
contexts
research
version
GUANinE v1.1
split
Test set
source locator
Table 2 column header
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