rewirebio.iobenchmarks
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scANVI (Seurat v3 2000 HVG)

scANVI: scANVI or "single-cell ANnotation using Variational Inference" is a semi-supervised variant of the scVI algorithm.

24 evaluations · 24 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

24 evaluations · 24 results. Different protocols are not a single leaderboard.

Sorted by Accuracy (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationProtocol and datasetAccuracyMacro F1Weighted F1
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-RANDOM-ACCURACY: Label projection on Pancreas (random split), Accuracy, Pancreas (random split) (Open Problems label projection split)0.978 (best in column)Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-RANDOM-LABEL-NOISE-ACCURACY: Label projection on Pancreas (random split with label noise), Accuracy, Pancreas (random split with label noise) (Open Problems label projection split)0.967Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-BATCH-ACCURACY: Label projection on Pancreas (by batch), Accuracy, Pancreas (by batch) (Open Problems label projection split)0.96Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-ACCURACY: Label projection on Tabula Muris Senis Lung (random split), Accuracy, Tabula Muris Senis Lung (random split) (Open Problems label projection split)0.841Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection ZEBRAFISH-RANDOM-ACCURACY: Label projection on Zebrafish (random split), Accuracy, Zebrafish (random split) (Open Problems label projection split)0.779Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection CENGEN-RANDOM-ACCURACY: Label projection on CeNGEN (random split), Accuracy, CeNGEN (random split) (Open Problems label projection split)0.652Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection CENGEN-BATCH-ACCURACY: Label projection on CeNGEN (split by batch), Accuracy, CeNGEN (split by batch) (Open Problems label projection split)0.262Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection ZEBRAFISH-LABS-ACCURACY: Label projection on Zebrafish (by laboratory), Accuracy, Zebrafish (by laboratory) (Open Problems label projection split)0.21Not reportedNot reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection CENGEN-BATCH-F1: Label projection on CeNGEN (split by batch), F1 score, CeNGEN (split by batch) (Open Problems label projection split)Not reportedNot reported0.224
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection CENGEN-BATCH-F1-MACRO: Label projection on CeNGEN (split by batch), Macro F1 score, CeNGEN (split by batch) (Open Problems label projection split)Not reported0.161Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection CENGEN-RANDOM-F1: Label projection on CeNGEN (random split), F1 score, CeNGEN (random split) (Open Problems label projection split)Not reportedNot reported0.569
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection CENGEN-RANDOM-F1-MACRO: Label projection on CeNGEN (random split), Macro F1 score, CeNGEN (random split) (Open Problems label projection split)Not reported0.235Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-BATCH-F1: Label projection on Pancreas (by batch), F1 score, Pancreas (by batch) (Open Problems label projection split)Not reportedNot reported0.958
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-BATCH-F1-MACRO: Label projection on Pancreas (by batch), Macro F1 score, Pancreas (by batch) (Open Problems label projection split)Not reported0.669Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-RANDOM-F1: Label projection on Pancreas (random split), F1 score, Pancreas (random split) (Open Problems label projection split)Not reportedNot reported0.976 (best in column)
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-RANDOM-F1-MACRO: Label projection on Pancreas (random split), Macro F1 score, Pancreas (random split) (Open Problems label projection split)Not reported0.687 (best in column)Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-RANDOM-LABEL-NOISE-F1: Label projection on Pancreas (random split with label noise), F1 score, Pancreas (random split with label noise) (Open Problems label projection split)Not reportedNot reported0.964
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection PANCREAS-RANDOM-LABEL-NOISE-F1-MACRO: Label projection on Pancreas (random split with label noise), Macro F1 score, Pancreas (random split with label noise) (Open Problems label projection split)Not reported0.685Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-F1: Label projection on Tabula Muris Senis Lung (random split), F1 score, Tabula Muris Senis Lung (random split) (Open Problems label projection split)Not reportedNot reported0.801
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-F1-MACRO: Label projection on Tabula Muris Senis Lung (random split), Macro F1 score, Tabula Muris Senis Lung (random split) (Open Problems label projection split)Not reported0.394Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection ZEBRAFISH-LABS-F1: Label projection on Zebrafish (by laboratory), F1 score, Zebrafish (by laboratory) (Open Problems label projection split)Not reportedNot reported0.226
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score, Zebrafish (by laboratory) (Open Problems label projection split)Not reported0.237Not reported
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection ZEBRAFISH-RANDOM-F1: Label projection on Zebrafish (random split), F1 score, Zebrafish (random split) (Open Problems label projection split)Not reportedNot reported0.728
scANVI (Seurat v3 2000 HVG)EvaluationOpen Problems label projection ZEBRAFISH-RANDOM-F1-MACRO: Label projection on Zebrafish (random split), Macro F1 score, Zebrafish (random split) (Open Problems label projection split)Not reported0.437Not reported
All 24 result rows with coverage, uncertainty and sources
Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection CENGEN-BATCH-ACCURACY: Label projection on CeNGEN (split by batch), Accuracy
Dataset subset: CeNGEN (split by batch) (Open Problems label projection split)
0.262 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection CENGEN-BATCH-ACCURACY: Label projection on CeNGEN (split by batch), Accuracy

100k FACS-isolated C. elegans neurons from 17 experiments sequenced on 10x Genomics. Split into train/test by experimental batch. Dimensions: 100955 cells, 22469 genes. 169 cell types (avg. 597±800 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(cengen_batch), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection CENGEN-BATCH-F1: Label projection on CeNGEN (split by batch), F1 score
Dataset subset: CeNGEN (split by batch) (Open Problems label projection split)
0.224 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection CENGEN-BATCH-F1: Label projection on CeNGEN (split by batch), F1 score

100k FACS-isolated C. elegans neurons from 17 experiments sequenced on 10x Genomics. Split into train/test by experimental batch. Dimensions: 100955 cells, 22469 genes. 169 cell types (avg. 597±800 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(cengen_batch), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection CENGEN-BATCH-F1-MACRO: Label projection on CeNGEN (split by batch), Macro F1 score
Dataset subset: CeNGEN (split by batch) (Open Problems label projection split)
0.161 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection CENGEN-BATCH-F1-MACRO: Label projection on CeNGEN (split by batch), Macro F1 score

100k FACS-isolated C. elegans neurons from 17 experiments sequenced on 10x Genomics. Split into train/test by experimental batch. Dimensions: 100955 cells, 22469 genes. 169 cell types (avg. 597±800 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(cengen_batch), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection CENGEN-RANDOM-ACCURACY: Label projection on CeNGEN (random split), Accuracy
Dataset subset: CeNGEN (random split) (Open Problems label projection split)
0.652 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection CENGEN-RANDOM-ACCURACY: Label projection on CeNGEN (random split), Accuracy

100k FACS-isolated C. elegans neurons from 17 experiments sequenced on 10x Genomics. Split into train/test randomly. Dimensions: 100955 cells, 22469 genes. 169 cell types avg. 597±800 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(cengen_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection CENGEN-RANDOM-F1: Label projection on CeNGEN (random split), F1 score
Dataset subset: CeNGEN (random split) (Open Problems label projection split)
0.569 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection CENGEN-RANDOM-F1: Label projection on CeNGEN (random split), F1 score

100k FACS-isolated C. elegans neurons from 17 experiments sequenced on 10x Genomics. Split into train/test randomly. Dimensions: 100955 cells, 22469 genes. 169 cell types avg. 597±800 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(cengen_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection CENGEN-RANDOM-F1-MACRO: Label projection on CeNGEN (random split), Macro F1 score
Dataset subset: CeNGEN (random split) (Open Problems label projection split)
0.235 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection CENGEN-RANDOM-F1-MACRO: Label projection on CeNGEN (random split), Macro F1 score

100k FACS-isolated C. elegans neurons from 17 experiments sequenced on 10x Genomics. Split into train/test randomly. Dimensions: 100955 cells, 22469 genes. 169 cell types avg. 597±800 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(cengen_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-BATCH-ACCURACY: Label projection on Pancreas (by batch), Accuracy
Dataset subset: Pancreas (by batch) (Open Problems label projection split)
0.96 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-BATCH-ACCURACY: Label projection on Pancreas (by batch), Accuracy

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test by experimental batch. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_batch), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-BATCH-F1: Label projection on Pancreas (by batch), F1 score
Dataset subset: Pancreas (by batch) (Open Problems label projection split)
0.958 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-BATCH-F1: Label projection on Pancreas (by batch), F1 score

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test by experimental batch. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_batch), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-BATCH-F1-MACRO: Label projection on Pancreas (by batch), Macro F1 score
Dataset subset: Pancreas (by batch) (Open Problems label projection split)
0.669 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-BATCH-F1-MACRO: Label projection on Pancreas (by batch), Macro F1 score

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test by experimental batch. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_batch), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-RANDOM-ACCURACY: Label projection on Pancreas (random split), Accuracy
Dataset subset: Pancreas (random split) (Open Problems label projection split)
0.978 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-RANDOM-ACCURACY: Label projection on Pancreas (random split), Accuracy

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test randomly. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-RANDOM-F1: Label projection on Pancreas (random split), F1 score
Dataset subset: Pancreas (random split) (Open Problems label projection split)
0.976 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-RANDOM-F1: Label projection on Pancreas (random split), F1 score

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test randomly. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-RANDOM-F1-MACRO: Label projection on Pancreas (random split), Macro F1 score
Dataset subset: Pancreas (random split) (Open Problems label projection split)
0.687 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-RANDOM-F1-MACRO: Label projection on Pancreas (random split), Macro F1 score

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test randomly. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-RANDOM-LABEL-NOISE-ACCURACY: Label projection on Pancreas (random split with label noise), Accuracy
Dataset subset: Pancreas (random split with label noise) (Open Problems label projection split)
0.967 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-RANDOM-LABEL-NOISE-ACCURACY: Label projection on Pancreas (random split with label noise), Accuracy

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test randomly with 20% label noise. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_random_label_noise), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-RANDOM-LABEL-NOISE-F1: Label projection on Pancreas (random split with label noise), F1 score
Dataset subset: Pancreas (random split with label noise) (Open Problems label projection split)
0.964 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-RANDOM-LABEL-NOISE-F1: Label projection on Pancreas (random split with label noise), F1 score

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test randomly with 20% label noise. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_random_label_noise), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection PANCREAS-RANDOM-LABEL-NOISE-F1-MACRO: Label projection on Pancreas (random split with label noise), Macro F1 score
Dataset subset: Pancreas (random split with label noise) (Open Problems label projection split)
0.685 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection PANCREAS-RANDOM-LABEL-NOISE-F1-MACRO: Label projection on Pancreas (random split with label noise), Macro F1 score

Human pancreatic islet scRNA-seq data from 6 datasets across technologies (CEL-seq, CEL-seq2, Smart-seq2, inDrop, Fluidigm C1, and SMARTER-seq). Split into train/test randomly with 20% label noise. Dimensions: 16382 cells, 18771 genes. 14 cell types (avg. 1170±1703 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(pancreas_random_label_noise), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-ACCURACY: Label projection on Tabula Muris Senis Lung (random split), Accuracy
Dataset subset: Tabula Muris Senis Lung (random split) (Open Problems label projection split)
0.841 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-ACCURACY: Label projection on Tabula Muris Senis Lung (random split), Accuracy

All lung cells from Tabula Muris Senis, a 500k cell-atlas from 18 organs and tissues across the mouse lifespan. Split into train/test randomly. Dimensions: 24540 cells, 17985 genes. 39 cell types (avg. 629±999 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(tabula_muris_senis_lung_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-F1: Label projection on Tabula Muris Senis Lung (random split), F1 score
Dataset subset: Tabula Muris Senis Lung (random split) (Open Problems label projection split)
0.801 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-F1: Label projection on Tabula Muris Senis Lung (random split), F1 score

All lung cells from Tabula Muris Senis, a 500k cell-atlas from 18 organs and tissues across the mouse lifespan. Split into train/test randomly. Dimensions: 24540 cells, 17985 genes. 39 cell types (avg. 629±999 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(tabula_muris_senis_lung_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-F1-MACRO: Label projection on Tabula Muris Senis Lung (random split), Macro F1 score
Dataset subset: Tabula Muris Senis Lung (random split) (Open Problems label projection split)
0.394 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection TABULA-MURIS-SENIS-LUNG-RANDOM-F1-MACRO: Label projection on Tabula Muris Senis Lung (random split), Macro F1 score

All lung cells from Tabula Muris Senis, a 500k cell-atlas from 18 organs and tissues across the mouse lifespan. Split into train/test randomly. Dimensions: 24540 cells, 17985 genes. 39 cell types (avg. 629±999 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(tabula_muris_senis_lung_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection ZEBRAFISH-LABS-ACCURACY: Label projection on Zebrafish (by laboratory), Accuracy
Dataset subset: Zebrafish (by laboratory) (Open Problems label projection split)
0.21 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-LABS-ACCURACY: Label projection on Zebrafish (by laboratory), Accuracy

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection ZEBRAFISH-LABS-F1: Label projection on Zebrafish (by laboratory), F1 score
Dataset subset: Zebrafish (by laboratory) (Open Problems label projection split)
0.226 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-LABS-F1: Label projection on Zebrafish (by laboratory), F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score
Dataset subset: Zebrafish (by laboratory) (Open Problems label projection split)
0.237 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection ZEBRAFISH-RANDOM-ACCURACY: Label projection on Zebrafish (random split), Accuracy
Dataset subset: Zebrafish (random split) (Open Problems label projection split)
0.779 Accuracy
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-RANDOM-ACCURACY: Label projection on Zebrafish (random split), Accuracy

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test randomly. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(zebrafish_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(accuracy)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection ZEBRAFISH-RANDOM-F1: Label projection on Zebrafish (random split), F1 score
Dataset subset: Zebrafish (random split) (Open Problems label projection split)
0.728 Weighted F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-RANDOM-F1: Label projection on Zebrafish (random split), F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test randomly. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(zebrafish_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1)
Configuration: scANVI (Seurat v3 2000 HVG)Task: Open Problems label projection ZEBRAFISH-RANDOM-F1-MACRO: Label projection on Zebrafish (random split), Macro F1 score
Dataset subset: Zebrafish (random split) (Open Problems label projection split)
0.437 Macro F1
fraction · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-RANDOM-F1-MACRO: Label projection on Zebrafish (random split), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test randomly. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Aggregation: Not reported

openproblems-label primary benchmark evidence · results, dataset(zebrafish_random), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

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Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

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Stable ID: open-problems-method-scanvi-seurat-v3-2000-hvg

areas
cells-tissues
source locator
results, method(scanvi), paramset(Seurat v3 2000 HVG)
missing metadata
checkpoint revision: reason: unreported; parameters: reason: unextracted
provenance note
scANVI or "single-cell ANnotation using Variational Inference" is a semi-supervised variant of the scVI(Lopez et al. 2018) algorithm. Like scVI, scANVI uses deep neural networks and stochastic optimization to model uncertainty caused by technical noise and bias in single - cell transcriptomics measurements. However, scANVI also leverages cell type labels in the generative modelling. In this approach, scANVI is used to predict the cell type labels of the unlabelled test data.
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