rewirebio.iobenchmarks

Biological models

Understand model architectures, biological inputs, access requirements and the evidence from linked evaluations.

318 model records in release 2026-10-23-5347695500ed (release manifest, gzip). Showing 193–216; page 9 of 14.

Evaluated configurations, methods and pipelines are listed separately. Names alone do not establish equivalent models or checkpoints.

  • MSNovelist

    Metabolomics

    MSNovelist de novo structure generation from fingerprints.

  • MULAN

    Proteins and complexes

    Multimodal protein language model that fuses a pretrained sequence encoder with a parameter-efficient adapter for angle-based structure encoding, scored in ProteinGym as a zero-shot substitution baseline from sequence and structure.

  • MutBERT

    DNA and genomes

    Masked DNA language model that represents the human genome as allele-frequency distributions from population data, so pretraining concentrates on sites of variation.

  • MVP

    Metabolomics

    Contrastive spectrum-to-molecule retrieval model that extends JESTR with multiple views (fingerprint, graph, spectra and consensus spectra); it needs the target's molecular formula.

  • NEIMS

    Metabolomics

    Neural electron-ionization mass spectrum predictor, used as a predictor head in FlexMS.

  • Neuraldecipher

    Metabolomics

    Neuraldecipher fingerprint-to-molecule decoder.

  • NeuralFP

    Protein function

    Neural fingerprint graph network.

  • Nicheformer

    Single-cell omics · Spatial omics

    Transformer foundation model pretrained on dissociated and spatial transcriptomics.

  • Novae

    Single-cell omics · Spatial omics

    Graph attention foundation model for spatial transcriptomics domains.

  • Nucleotide Transformer

    DNA and genomes

    Nucleotide Transformer is a family of DNA encoders pretrained on human or multispecies sequence corpora.

  • Nucleotide Transformer v2

    DNA and genomes

    Nucleotide Transformer v2 represents DNA using an encoder pretrained on multiple species.

  • Nucleotide Transformer v3

    DNA and genomes

    Nucleotide Transformer v3 genomic language model family (pre- and post-trained checkpoints).

  • NuFold

    RNA and transcriptomes · Protein structure

    NuFold: RNA 3D structure prediction method built on the AlphaFold architecture with RNA-specific inputs.

  • o1

    Cells and tissues

    OpenAI reasoning language model that generates an internal chain of thought before giving its answer.

  • o1-mini

    Cells and tissues

    Faster version of OpenAI's o1 reasoning model, trained with reinforcement learning to think in a chain of thought before answering and particularly effective at coding.

  • o1-preview

    Cells and tissues

    Preview release of OpenAI's o1 reasoning model, a large language model trained with reinforcement learning to produce a long chain of thought before answering.

  • Omni-DNA

    DNA and genomes

    Autoregressive transformer family pretrained on DNA by next-token prediction and then fine-tuned with added task tokens to solve several genomic tasks, including DNA-to-text and DNA-to-image mapping, in one model.

    Record: gfm2-20261011-datta2026-model-omni-dna

  • Omni-DNA

    DNA and genomes

    Family of autoregressive DNA transformers from 20 million to 1 billion parameters, pretrained by next-token prediction and multi-task fine-tuned with added task tokens for classification and cross-modal outputs.

    Record: lit-genomics-20261011-geneb-model-omni-dna

  • OmniNA

    DNA and genomes

    Generative nucleotide model pretrained on 91.7 million sequences with their text annotations from many species, fine-tuned to answer sequence tasks in natural language.

  • OmniReg-GPT

    Microbes and communities · DNA and genomes

    OmniReg-GPT generative genomic foundation model.

  • OpenFold

    Protein structure

    OpenFold is a trainable PyTorch implementation of AlphaFold 2 and AlphaFold-Multimer workflows.

  • OpenSpliceAI

    DNA and genomes

    PyTorch reimplementation of SpliceAI retrained on RefSeq MANE v1.3 protein-coding transcripts (GRCh38).

  • Optimus 5-Prime

    RNA and transcriptomes

    Convolutional neural network that predicts mean ribosome load from 5' UTR sequence, trained on massively parallel reporter assays of random 5' UTRs and limited by position-specific weights to the lengths seen in training.

  • Orca

    DNA and genomes

    Orca 3D genome structure model.

This index reflects a dated catalogue, not an exhaustive census. Source checking does not mean independent reproduction; compare results only under compatible protocols, datasets and metrics.