Biological models
Understand model architectures, biological inputs, access requirements and the evidence from linked evaluations.
318 model records in release 2026-10-23-5347695500ed (release manifest, gzip). Showing 289–312; page 13 of 14.
Evaluated configurations, methods and pipelines are listed separately. Names alone do not establish equivalent models or checkpoints.
SpliceBERT
DNA and genomes
BERT-style RNA language model trained by masked token prediction on precursor RNA from 72 vertebrate species, used for splice site, branchpoint and splicing variant effect prediction.
Record: lit-genomics-20261011-geneb-model-splicebert
SpTransformer
DNA and genomes
Task-specific transformer for tissue-specific splice site prediction.
STATE
Single-cell omics
State separates cellular representation learning from prediction of responses to perturbation.
SweetNet
Glycans
SweetNet predicts glycan properties and produces learned representations from glycan graphs.
TAPE Bepler
Protein function
The TAPE Bepler comparison uses a protein representation that combines bidirectional language modelling with supervised structural pretraining.
TAPE LSTM
Protein function
The TAPE LSTM baseline represents protein sequences using recurrent networks that read residues in both directions.
TAPE ResNet
Protein function
The TAPE ResNet baseline represents protein sequences using residual convolutional blocks before a task-specific prediction head.
TAPE Transformer
Protein function
The TAPE Transformer learns contextual protein representations using masked-residue pretraining and a task-specific prediction head.
TAPE Unirep
Protein function
The TAPE UniRep baseline uses a multiplicative recurrent network to represent protein sequences for downstream tasks.
text-embedding-3-large
Cells and tissues
OpenAI text embedding model that maps a text string to a 3,072-dimensional vector.
TranceptEVE
Proteins and complexes
Hybrid of a family-agnostic autoregressive transformer and family-specific alignment-based models that relies more on the alignment models as alignment depth grows, scored in ProteinGym as a zero-shot substitution baseline.
Tranception
Proteins and complexes
Autoregressive transformer protein language model that can retrieve homologous sequences at inference to predict the fitness of substitutions, multiple mutants and indels; ProteinGym scores it with and without retrieval as a zero-shot substitution baseline.
Transformer
Protein function
Transformer encoder trained from scratch on the task's sequences.
TREDNet
DNA and genomes
Two-phase CNN for enhancer prediction and variant prioritisation, developed by the group of the senior author of the comparison that evaluated it.
trRosettaRNA
RNA and transcriptomes · Protein structure
trRosettaRNA: MSA and pair representations fed into the RNAformer transformer, followed by 3D folding.
UCE (Universal Cell Embeddings)
Cells and tissues
Single-cell foundation model producing cell embeddings from protein-embedded gene tokens.
Uni-RNA
RNA and transcriptomes
Uni-RNA RNA foundation model (L8, L12 and L16 checkpoints).
Unirep
Proteins and complexes
Deep learning representation of protein sequences learned from unlabeled amino-acid sequences, on which simple models predict stability and mutant function, scored in ProteinGym as a zero-shot single-sequence substitution baseline.
Unirep evotuned
Proteins and complexes
Evo-tuned variant of UniRep, a protein sequence representation learned from unlabeled amino-acid sequences, which ProteinGym lists as using a multiple sequence alignment for evo-tuning and scores as a zero-shot substitution baseline.
UniSpec
Proteins and complexes
UniSpec attention-based fragment dictionary model (about 12M parameters).
UTR-LM
DNA and genomes
Language model pre-trained on 5' untranslated region sequence.
VenusREM
Proteins and complexes
Retrieval-enhanced protein language model that captures local amino acid interactions for mutation effect prediction, scored in ProteinGym as a zero-shot substitution baseline from alignment and structure inputs.
VESPA
Proteins and complexes
Logistic regression ensemble that predicts single amino acid variant effects without alignments from protein language model embeddings, combining predicted conservation, BLOSUM62 scores and language-model mask reconstruction probabilities; scored in ProteinGym as a zero-shot substitution baseline.
VespaG
Proteins and complexes
Missense variant effect predictor that feeds protein language model embeddings to a minimal deep learning model trained on GEMME predictions for 39 million human variants, scored in ProteinGym as a substitution baseline.
This index reflects a dated catalogue, not an exhaustive census. Source checking does not mean independent reproduction; compare results only under compatible protocols, datasets and metrics.