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FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split

GB1 fitness prediction, 2-vs-rest split. Scored with Spearman correlation on FLIP GB1, 2-vs-rest split. Trained on the split's training set with ten percent held out for validation, scored on its test set.

13 evaluations · 13 results

Overview

GB1 fitness prediction, 2-vs-rest split. Scored with Spearman correlation on FLIP GB1, 2-vs-rest split. Trained on the split's training set with ten percent held out for validation, scored on its test set.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Results

Each comparison retains its reviewed evaluation scope, dataset and metric. Results are shown without a pooled ranking.

FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split

spearman (correlation) · Higher values are better.

FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split · FLIP GB1, 2-vs-rest split (FLIP split)

Evidence origin: Author-reported evaluation.

flip primary benchmark evidence · Table 4, column(2-vs-rest)
  • The split is the task here. Figures from different splits of the same landscape are not comparable.
  • The random sampled splits in Table 7 are the authors' own illustration of an optimistic evaluation, not a headline result.
  • NA marks a baseline that cannot be applied to that landscape, and is recorded as no result rather than as a zero.
Comparison details and limitations

Every method FLIP reports on GB1 fitness prediction, 2-vs-rest split, scored with Spearman correlation on FLIP GB1, 2-vs-rest split.

  • Author-reported numbers, source checked but not independently reproduced.

Automated source review: 2026-09-18. Numerical source review does not establish independent reproduction.

Dots show point estimates. Whiskers show only explicitly defined uncertainty (standard deviation, standard error or a labelled interval); their definitions remain in Table. Unresolved uncertainty is not plotted. Differences do not establish statistical significance.

Showing 12 of 13 matching rows.

Tested configuration
-1-0.500.51
Reported score
  1. Ridge0.59
  2. ESM-1b (per AA)0.55
  3. ESM-1b (mean)0.36
  4. ESM-1v (mean)0.32
  5. CNN0.32
  6. ESM-1v (per AA)0.28
  7. ESM-untrained (mut mean)0.21
  8. ESM-1b (mut mean)0.19
  9. ESM-1v (mut mean)0.19
  10. Levenshtein0.16
  11. BLOSUM620.14
  12. ESM-untrained (per AA)0.06

Methods and evaluation design

Procedure, tasks and evaluated configurations

Evaluation design

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Benchmarks

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Strengths, limitations and unresolved questions

Evidence

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Evidence table

Inspect claims, sources and review details

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1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
Relationship: part of
discovery-benchmark-flip
Individual claims		flip primary benchmark evidence

Original source ↗

Table 4, column(2-vs-rest)

Version: 2021 manuscript
Retrieved: 2026-09-16T21:07:13.889041+00:00

source checked

automated source review · 2026-09-18

Audit details

Primary-source transcription with no human sign-off and no independent reproduction.

Field: links:part_of:discovery-benchmark-flip

Claim: flip-association-gb1-2-vs-rest

Source artifact SHA-256: afcf360c88a7a4ae153b3c2d8d4fa6d4ac0abe84f2131b94409abff6447ce363

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

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Sources and history

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Release 2026-09-29-06401fd5b220 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: flip-task-gb1-2-vs-rest

areas
proteins-complexes
tasks
GB1 fitness prediction, 2-vs-rest split
metric
Spearman correlation
metric direction
higher
dataset
FLIP GB1, 2-vs-rest split
protocol
Trained on the split's training set with ten percent held out for validation, scored on its test set.
source locator
Table 4, column(2-vs-rest)
comparison panels
id: flip-panel-gb1-2-vs-rest; title: FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split; protocol id: flip-task-gb1-2-vs-rest; dataset id: flip-dataset-flip-gb1-2-vs-rest-split; metric: spearman; unit: correlation; direction: higher; result ids: flip-result-esm-1b-per-aa-gb1-2-vs-rest-spearman; flip-result-esm-1b-mean-gb1-2-vs-rest-spearman; flip-result-esm-1b-mut-mean-gb1-2-vs-rest-spearman; flip-result-esm-1v-per-aa-gb1-2-vs-rest-spearman; flip-result-esm-1v-mean-gb1-2-vs-rest-spearman; flip-result-esm-1v-mut-mean-gb1-2-vs-rest-spearman; flip-result-esm-untrained-per-aa-gb1-2-vs-rest-spearman; flip-result-esm-untrained-mean-gb1-2-vs-rest-spearman; flip-result-esm-untrained-mut-mean-gb1-2-vs-rest-spearman; flip-result-ridge-gb1-2-vs-rest-spearman; flip-result-cnn-gb1-2-vs-rest-spearman; flip-result-levenshtein-gb1-2-vs-rest-spearman; flip-result-blosum62-gb1-2-vs-rest-spearman; source ids: expansion-p3-flip; source locator: Table 4, column(2-vs-rest); context: Every method FLIP reports on GB1 fitness prediction, 2-vs-rest split, scored with Spearman correlation on FLIP GB1, 2-vs-rest split.; caveats: Author-reported numbers, source checked but not independently reproduced.; The split is the task here. Figures from different splits of the same landscape are not comparable.; The random sampled splits in Table 7 are the authors' own illustration of an optimistic evaluation, not a headline result.; NA marks a baseline that cannot be applied to that landscape, and is recorded as no result rather than as a zero.; review: method: automated_source_review; date: 2026-09-18
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