ESM-untrained (mut mean)
Protein language model embedding with the stated pooling, fed to a supervised head by the FLIP authors.
Overview
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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
10 evaluations · 10 results. Different protocols are not a single leaderboard.
Sorted by Spearman (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
All 10 result rows with coverage, uncertainty and sources
Filter evaluations
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: ESM-untrained (mut mean) | Task: FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split Dataset subset: FLIP AAV, 1-vs-rest split (FLIP split) | 0.26 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-untrained (mut mean)), column(1-vs-rest) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP AAV-2-VS-REST: AAV fitness prediction, 2-vs-rest split Dataset subset: FLIP AAV, 2-vs-rest split (FLIP split) | 0.16 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP AAV-2-VS-REST: AAV fitness prediction, 2-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-untrained (mut mean)), column(2-vs-rest) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP AAV-7-VS-REST: AAV fitness prediction, 7-vs-rest split Dataset subset: FLIP AAV, 7-vs-rest split (FLIP split) | 0.56 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP AAV-7-VS-REST: AAV fitness prediction, 7-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-untrained (mut mean)), column(7-vs-rest) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP AAV-DES-MUT: AAV fitness prediction, Des-Mut split Dataset subset: FLIP AAV, Des-Mut split (FLIP split) | 0.64 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP AAV-DES-MUT: AAV fitness prediction, Des-Mut split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-untrained (mut mean)), column(Des-Mut) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP AAV-LOW-VS-HIGH: AAV fitness prediction, low-vs-high split Dataset subset: FLIP AAV, low-vs-high split (FLIP split) | 0.24 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP AAV-LOW-VS-HIGH: AAV fitness prediction, low-vs-high split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-untrained (mut mean)), column(low-vs-high) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP AAV-MUT-DES: AAV fitness prediction, Mut-Des split Dataset subset: FLIP AAV, Mut-Des split (FLIP split) | 0.62 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP AAV-MUT-DES: AAV fitness prediction, Mut-Des split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-untrained (mut mean)), column(Mut-Des) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split Dataset subset: FLIP GB1, 1-vs-rest split (FLIP split) | 0.21 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-untrained (mut mean)), column(1-vs-rest) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split Dataset subset: FLIP GB1, 2-vs-rest split (FLIP split) | 0.21 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-untrained (mut mean)), column(2-vs-rest) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split Dataset subset: FLIP GB1, 3-vs-rest split (FLIP split) | 0.57 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-untrained (mut mean)), column(3-vs-rest) |
| Configuration: ESM-untrained (mut mean) | Task: FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split Dataset subset: FLIP GB1, low-vs-high split (FLIP split) | 0.13 Spearman unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (mut mean) on FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-untrained (mut mean)), column(low-vs-high) |
Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.
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How it works, versions and access
Additional methodological details, versions and access terms have not yet been extracted into a structured profile for this configuration. Consult the linked sources and evaluation records below.
Evidence
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Evidence table
Inspect claims, sources and review details
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Sources and history
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
1 source record and release history
- flip primary benchmark evidence · Original source · 2021 manuscript
Technical metadata and extraction receipts
Stable ID: flip-method-esm-untrained-mut-mean
- areas
- proteins-complexes
- source locator
- Table 4, row(ESM-untrained (mut mean))
- missing metadata
- checkpoint revision: reason: unreported; parameters: reason: unextracted
Related records
- system: ESM-untrained (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- system: ESM-untrained (mut mean) on FLIP AAV-2-VS-REST: AAV fitness prediction, 2-vs-rest split
- system: ESM-untrained (mut mean) on FLIP AAV-7-VS-REST: AAV fitness prediction, 7-vs-rest split
- system: ESM-untrained (mut mean) on FLIP AAV-DES-MUT: AAV fitness prediction, Des-Mut split
- system: ESM-untrained (mut mean) on FLIP AAV-LOW-VS-HIGH: AAV fitness prediction, low-vs-high split
- system: ESM-untrained (mut mean) on FLIP AAV-MUT-DES: AAV fitness prediction, Mut-Des split
- system: ESM-untrained (mut mean) on FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split
- system: ESM-untrained (mut mean) on FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split
- system: ESM-untrained (mut mean) on FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split
- system: ESM-untrained (mut mean) on FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split