FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
AAV fitness prediction, 1-vs-rest split. Scored with Spearman correlation on FLIP AAV, 1-vs-rest split. Trained on the split's training set with ten percent held out for validation, scored on its test set.
Overview
AAV fitness prediction, 1-vs-rest split. Scored with Spearman correlation on FLIP AAV, 1-vs-rest split. Trained on the split's training set with ten percent held out for validation, scored on its test set.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Results
Each comparison retains its reviewed evaluation scope, dataset and metric. Results are shown without a pooled ranking.
FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
spearman (correlation) · Higher values are better.
FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split · FLIP AAV, 1-vs-rest split (FLIP split)
Evidence origin: Author-reported evaluation.
flip primary benchmark evidence · Table 5, column(1-vs-rest)- The split is the task here. Figures from different splits of the same landscape are not comparable.
- The random sampled splits in Table 7 are the authors' own illustration of an optimistic evaluation, not a headline result.
- NA marks a baseline that cannot be applied to that landscape, and is recorded as no result rather than as a zero.
Comparison details and limitations
Every method FLIP reports on AAV fitness prediction, 1-vs-rest split, scored with Spearman correlation on FLIP AAV, 1-vs-rest split.
- Author-reported numbers, source checked but not independently reproduced.
Automated source review: 2026-09-18. Numerical source review does not establish independent reproduction.
Dots show point estimates. Whiskers show only explicitly defined uncertainty (standard deviation, standard error or a labelled interval); their definitions remain in Table. Unresolved uncertainty is not plotted. Differences do not establish statistical significance.
Showing 12 of 12 matching rows.
Methods and evaluation design
Procedure, tasks and evaluated configurations
Evaluation design
Benchmarks bring together tasks and protocols. A task describes the biological question; a protocol defines a particular test.
Benchmarks
These source-backed links do not make different protocols or scores interchangeable.
Recorded evaluations
Each evaluation records what was tested and under which conditions.
- CNN on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-1b (mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-1b (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-1b (per AA) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-1v (mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-1v (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-1v (per AA) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-untrained (mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-untrained (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- ESM-untrained (per AA) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- Levenshtein on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- Ridge on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
Run instructions
No runnable recipe has been reviewed for this task. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.
A task describes a biological question. Choose a linked protocol to obtain concrete split and scoring instructions.
Strengths, limitations and unresolved questions
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Relationship: part of discovery-benchmark-flip Individual claims | flip primary benchmark evidence Table 5, column(1-vs-rest) Version: 2021 manuscript | source checked automated source review · 2026-09-18 Audit detailsPrimary-source transcription with no human sign-off and no independent reproduction. Field: Claim: flip-association-aav-1-vs-rest Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
Sources and history
View linked audit checks and correction history
Release 2026-09-29-06401fd5b220 · Record review: source checked
1 source records and release history
- flip primary benchmark evidence · Original source · 2021 manuscript
Technical metadata and extraction receipts
Stable ID: flip-task-aav-1-vs-rest
- areas
- proteins-complexes
- tasks
- AAV fitness prediction, 1-vs-rest split
- metric
- Spearman correlation
- metric direction
- higher
- dataset
- FLIP AAV, 1-vs-rest split
- protocol
- Trained on the split's training set with ten percent held out for validation, scored on its test set.
- source locator
- Table 5, column(1-vs-rest)
- comparison panels
- id: flip-panel-aav-1-vs-rest; title: FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split; protocol id: flip-task-aav-1-vs-rest; dataset id: flip-dataset-flip-aav-1-vs-rest-split; metric: spearman; unit: correlation; direction: higher; result ids: flip-result-esm-1b-per-aa-aav-1-vs-rest-spearman; flip-result-esm-1b-mean-aav-1-vs-rest-spearman; flip-result-esm-1b-mut-mean-aav-1-vs-rest-spearman; flip-result-esm-1v-per-aa-aav-1-vs-rest-spearman; flip-result-esm-1v-mean-aav-1-vs-rest-spearman; flip-result-esm-1v-mut-mean-aav-1-vs-rest-spearman; flip-result-esm-untrained-per-aa-aav-1-vs-rest-spearman; flip-result-esm-untrained-mean-aav-1-vs-rest-spearman; flip-result-esm-untrained-mut-mean-aav-1-vs-rest-spearman; flip-result-ridge-aav-1-vs-rest-spearman; flip-result-cnn-aav-1-vs-rest-spearman; flip-result-levenshtein-aav-1-vs-rest-spearman; source ids: expansion-p3-flip; source locator: Table 5, column(1-vs-rest); context: Every method FLIP reports on AAV fitness prediction, 1-vs-rest split, scored with Spearman correlation on FLIP AAV, 1-vs-rest split.; caveats: Author-reported numbers, source checked but not independently reproduced.; The split is the task here. Figures from different splits of the same landscape are not comparable.; The random sampled splits in Table 7 are the authors' own illustration of an optimistic evaluation, not a headline result.; NA marks a baseline that cannot be applied to that landscape, and is recorded as no result rather than as a zero.; review: method: automated_source_review; date: 2026-09-18
Related records
- part of: FLIP
- subject: FLIP AAV-1-VS-REST: part of discovery-benchmark-flip
- benchmark: CNN on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-1b (mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-1b (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-1b (per AA) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-1v (mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-1v (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-1v (per AA) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-untrained (mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-untrained (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: ESM-untrained (per AA) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: Levenshtein on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- benchmark: Ridge on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split