ESM-1v (mut mean)
Protein language model embedding with the stated pooling, fed to a supervised head by the FLIP authors.
Overview
Protein language model embedding with the stated pooling, fed to a supervised head by the FLIP authors.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
10 evaluations · 10 results. Different protocols are not a single leaderboard.
Filter evaluations
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: ESM-1v (mut mean) | Task: FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split Dataset subset: FLIP AAV, 1-vs-rest split (FLIP split) | 0.44 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-1v (mut mean)), column(1-vs-rest) |
| Configuration: ESM-1v (mut mean) | Task: FLIP AAV-2-VS-REST: AAV fitness prediction, 2-vs-rest split Dataset subset: FLIP AAV, 2-vs-rest split (FLIP split) | 0.64 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP AAV-2-VS-REST: AAV fitness prediction, 2-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-1v (mut mean)), column(2-vs-rest) |
| Configuration: ESM-1v (mut mean) | Task: FLIP AAV-7-VS-REST: AAV fitness prediction, 7-vs-rest split Dataset subset: FLIP AAV, 7-vs-rest split (FLIP split) | 0.64 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP AAV-7-VS-REST: AAV fitness prediction, 7-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-1v (mut mean)), column(7-vs-rest) |
| Configuration: ESM-1v (mut mean) | Task: FLIP AAV-DES-MUT: AAV fitness prediction, Des-Mut split Dataset subset: FLIP AAV, Des-Mut split (FLIP split) | 0.71 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP AAV-DES-MUT: AAV fitness prediction, Des-Mut split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-1v (mut mean)), column(Des-Mut) |
| Configuration: ESM-1v (mut mean) | Task: FLIP AAV-LOW-VS-HIGH: AAV fitness prediction, low-vs-high split Dataset subset: FLIP AAV, low-vs-high split (FLIP split) | 0.31 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP AAV-LOW-VS-HIGH: AAV fitness prediction, low-vs-high split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-1v (mut mean)), column(low-vs-high) |
| Configuration: ESM-1v (mut mean) | Task: FLIP AAV-MUT-DES: AAV fitness prediction, Mut-Des split Dataset subset: FLIP AAV, Mut-Des split (FLIP split) | 0.7 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP AAV-MUT-DES: AAV fitness prediction, Mut-Des split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 5, row(ESM-1v (mut mean)), column(Mut-Des) |
| Configuration: ESM-1v (mut mean) | Task: FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split Dataset subset: FLIP GB1, 1-vs-rest split (FLIP split) | 0.19 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-1v (mut mean)), column(1-vs-rest) |
| Configuration: ESM-1v (mut mean) | Task: FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split Dataset subset: FLIP GB1, 2-vs-rest split (FLIP split) | 0.19 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-1v (mut mean)), column(2-vs-rest) |
| Configuration: ESM-1v (mut mean) | Task: FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split Dataset subset: FLIP GB1, 3-vs-rest split (FLIP split) | 0.8 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-1v (mut mean)), column(3-vs-rest) |
| Configuration: ESM-1v (mut mean) | Task: FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split Dataset subset: FLIP GB1, low-vs-high split (FLIP split) | 0.49 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (mut mean) on FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split Trained on the split's training set with ten percent held out for validation, scored on its test set. Aggregation: Not reported flip primary benchmark evidence · Table 4, row(ESM-1v (mut mean)), column(low-vs-high) |
Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.
Use this model
How it works, versions and access
Underlying model: ESM-1v. Results on this page belong to this configuration and its evaluated settings.
Strengths, limitations and unresolved questions
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Relationship: uses model discovery-model-esm-1v Individual claims | flip primary benchmark evidence Table 3 Baseline methods; pooling methods immediately below; Tables 4–6 Version: 2021 manuscript | source checked automated source review · 2026-09-23 Audit detailsSource review establishes this relationship only. Exact evaluated configurations and original numerical review status remain unchanged. FLIP uses one ESM-1v ensemble member to produce frozen embeddings for a separately trained pooling/prediction model. Preserve composition with uses_model despite current configuration kind. Field: Claim: model-evaluation-identity-ecaba7a47380b1e4470c Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
Sources and history
View linked audit checks and correction history
Release 2026-09-29-06401fd5b220 · Record review: source checked
1 source records and release history
- flip primary benchmark evidence · Original source · 2021 manuscript
Technical metadata and extraction receipts
Stable ID: flip-method-esm-1v-mut-mean
- areas
- proteins-complexes
- source locator
- Table 4, row(ESM-1v (mut mean))
- missing metadata
- checkpoint revision: unreported; parameters: unextracted
Related records
- uses model: ESM-1v
- model: ESM-1v (mut mean) on FLIP AAV-1-VS-REST: AAV fitness prediction, 1-vs-rest split
- model: ESM-1v (mut mean) on FLIP AAV-2-VS-REST: AAV fitness prediction, 2-vs-rest split
- model: ESM-1v (mut mean) on FLIP AAV-7-VS-REST: AAV fitness prediction, 7-vs-rest split
- model: ESM-1v (mut mean) on FLIP AAV-DES-MUT: AAV fitness prediction, Des-Mut split
- model: ESM-1v (mut mean) on FLIP AAV-LOW-VS-HIGH: AAV fitness prediction, low-vs-high split
- model: ESM-1v (mut mean) on FLIP AAV-MUT-DES: AAV fitness prediction, Mut-Des split
- model: ESM-1v (mut mean) on FLIP GB1-1-VS-REST: GB1 fitness prediction, 1-vs-rest split
- model: ESM-1v (mut mean) on FLIP GB1-2-VS-REST: GB1 fitness prediction, 2-vs-rest split
- model: ESM-1v (mut mean) on FLIP GB1-3-VS-REST: GB1 fitness prediction, 3-vs-rest split
- model: ESM-1v (mut mean) on FLIP GB1-LOW-VS-HIGH: GB1 fitness prediction, low-vs-high split
- subject: ESM-1v (mut mean): uses model ESM-1v