rewirebio.iobenchmarks
Dataset

RNAGym Ribozyme DMS assays (26)

The 26 RNAGym Ribozyme deep mutational scanning assays used by the v0.1.1 fitness leaderboard.

Evaluation results

16 evaluations · 16 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: AIDO.RNA (1.6B) (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.074 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA (1.6B) on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'AIDO.RNA (1.6B)', column 'Ribozyme (n=26)'
Configuration: AIDO.RNA-1M-MARS (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.0015 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA-1M-MARS on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, 'AIDO.RNA across model sizes' table, row 'AIDO.RNA-1M-MARS', column 'Ribozyme'
Configuration: AIDO.RNA-25M-MARS (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
-0.0009 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA-25M-MARS on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, 'AIDO.RNA across model sizes' table, row 'AIDO.RNA-25M-MARS', column 'Ribozyme'
Configuration: AIDO.RNA-300M-MARS (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.0058 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA-300M-MARS on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, 'AIDO.RNA across model sizes' table, row 'AIDO.RNA-300M-MARS', column 'Ribozyme'
Configuration: AIDO.RNA-650M (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.046 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

AIDO.RNA-650M on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, 'AIDO.RNA across model sizes' table, row 'AIDO.RNA-650M', column 'Ribozyme'
Configuration: Evo 1.5 (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.0278 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo 1.5 on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'Evo 1.5', column 'Ribozyme (n=26)'
Configuration: Evo 1 (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
-0.0216 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo 1 on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'Evo 1', column 'Ribozyme (n=26)'
Configuration: Evo 2 (40B) (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.108 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo 2 (40B) on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'Evo 2 (40B)', column 'Ribozyme (n=26)'
Configuration: Evo 2 (7B) (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.0651 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Evo 2 (7B) on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'Evo 2 (7B)', column 'Ribozyme (n=26)'
Configuration: GenSLM (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
-0.0045 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GenSLM on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'GenSLM', column 'Ribozyme (n=26)'
Configuration: Nucleotide Transformer (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.133 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Nucleotide Transformer on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'Nucleotide Transformer', column 'Ribozyme (n=26)'
Configuration: Orthrus (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
-0.0276 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Orthrus on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'Orthrus', column 'Ribozyme (n=26)'
Configuration: RiNALMo (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
-0.0092 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RiNALMo on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'RiNALMo', column 'Ribozyme (n=26)'
Configuration: RNA-ERNIE (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.134 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNA-ERNIE on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'RNA-ERNIE', column 'Ribozyme (n=26)'
Configuration: RNA-FM (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
-0.0303 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNA-FM on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'RNA-FM', column 'Ribozyme (n=26)'
Configuration: RNAGenesis (RNAGym fitness leaderboard v0.1.1)Protocol: RNAGym v0.1.1 fitness, signed Spearman, Ribozyme
Dataset: RNAGym Ribozyme DMS assays (26)
0.0465 Spearman (mean signed Spearman over the 26 Ribozyme assays)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

RNAGenesis on RNAGym v0.1.1 fitness (Ribozyme)

lit-rna-20261011-rnagym-protocol-signed-spearman-ribozyme

Aggregation: Not reported

RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md · leaderboard/fitness/README.md, main leaderboard table, row 'RNAGenesis', column 'Ribozyme (n=26)'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
  • Compute requirements are estimated: not yet verified

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

5 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Source location
Leaderboard README 'Notes'
Context-only references
RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md

Original source ↗

Leaderboard README 'Notes'

Version: Commit 2828cf99316d75daaa8d832a2573cbb25bbd35fe (2026-08-14, 'Update fitness leaderboard v0.2 models'); leaderboard labelled v0.1.1
Retrieved: 2026-10-11T21:40:04Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: c947a7a45a53cc4106323a3bcae1bb3fa84276bc07df89493cb501735711b891

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Split
Whole assays (zero-shot)
Context-only references
RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md

Original source ↗

Leaderboard README 'Notes'

Version: Commit 2828cf99316d75daaa8d832a2573cbb25bbd35fe (2026-08-14, 'Update fitness leaderboard v0.2 models'); leaderboard labelled v0.1.1
Retrieved: 2026-10-11T21:40:04Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.split

Source artifact SHA-256: c947a7a45a53cc4106323a3bcae1bb3fa84276bc07df89493cb501735711b891

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Version
RNAGym v0.1.1
Context-only references
RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md

Original source ↗

Leaderboard README 'Notes'

Version: Commit 2828cf99316d75daaa8d832a2573cbb25bbd35fe (2026-08-14, 'Update fitness leaderboard v0.2 models'); leaderboard labelled v0.1.1
Retrieved: 2026-10-11T21:40:04Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.version

Source artifact SHA-256: c947a7a45a53cc4106323a3bcae1bb3fa84276bc07df89493cb501735711b891

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
The 26 RNAGym Ribozyme deep mutational scanning assays used by the v0.1.1 fitness leaderboard.
Context-only references
RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md

Original source ↗

Leaderboard README 'Notes'

Version: Commit 2828cf99316d75daaa8d832a2573cbb25bbd35fe (2026-08-14, 'Update fitness leaderboard v0.2 models'); leaderboard labelled v0.1.1
Retrieved: 2026-10-11T21:40:04Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: c947a7a45a53cc4106323a3bcae1bb3fa84276bc07df89493cb501735711b891

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
RNAGym Ribozyme DMS assays (26)
Context-only references
RNAGym fitness leaderboard (v0.1.1), leaderboard/fitness/README.md

Original source ↗

Leaderboard README 'Notes'

Version: Commit 2828cf99316d75daaa8d832a2573cbb25bbd35fe (2026-08-14, 'Update fitness leaderboard v0.2 models'); leaderboard labelled v0.1.1
Retrieved: 2026-10-11T21:40:04Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: c947a7a45a53cc4106323a3bcae1bb3fa84276bc07df89493cb501735711b891

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: lit-rna-20261011-rnagym-data-ribozyme

areas
rna-transcriptomes
contexts
research
version
RNAGym v0.1.1
split
Whole assays (zero-shot)
source locator
Leaderboard README 'Notes'
Related records

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