Proxy deleteriousness of hg38 SNVs (CADD-style proxy labels; Nazaretyan et al. 2025).
23 evaluations · 23 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Borzoi (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 21 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'Borzoi', column 'cadd-snv' (ρ) |
| Configuration: CADD v1.7 (Position) (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 19.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCADD v1.7 (Position) on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'CADD v1.7 (Position)', column 'cadd-snv' (ρ) |
| Configuration: CADD v1.7 (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 18.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'CADD v1.7', column 'cadd-snv' (ρ) |
| Configuration: ChromBPNet-ATAC-F0 (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 17.3 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceChromBPNet-ATAC-F0 on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'ChromBPNet-ATAC-F0', column 'cadd-snv' (ρ) |
| Configuration: ChromBPNet-ATAC-F3 (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 16.8 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceChromBPNet-ATAC-F3 on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'ChromBPNet-ATAC-F3', column 'cadd-snv' (ρ) |
| Configuration: deltaSVM GM12878 DHS (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 7.61 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcedeltaSVM GM12878 DHS on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'deltaSVM GM12878 DHS', column 'cadd-snv' (ρ) |
| Configuration: Enformer (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 17.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'Enformer', column 'cadd-snv' (ρ) |
| Configuration: Evo2_1B_base (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 24.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEvo2_1B_base on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'Evo2_1B_base', column 'cadd-snv' (ρ) |
| Configuration: GC-content (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 1.47 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceGC-content on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'GC-content', column 'cadd-snv' (ρ) |
| Configuration: GPN-MSA (Position) (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 26.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPN-MSA (Position) on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'GPN-MSA (Position)', column 'cadd-snv' (ρ) |
| Configuration: GPN-MSA (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 29.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'GPN-MSA', column 'cadd-snv' (ρ) |
| Configuration: Naïve VEP 115 Conseq. (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 0.16 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNaïve VEP 115 Conseq. on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'Naïve VEP 115 Conseq.', column 'cadd-snv' (ρ) |
| Configuration: NTv2-100m (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 23.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'NTv2-100m', column 'cadd-snv' (ρ) |
| Configuration: NTv2-250m (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 25.4 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'NTv2-250m', column 'cadd-snv' (ρ) |
| Configuration: NTv2-500m (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 26.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'NTv2-500m', column 'cadd-snv' (ρ) |
| Configuration: NTv3-100m-post (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 22.1 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNTv3-100m-post on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'NTv3-100m-post', column 'cadd-snv' (ρ) |
| Configuration: NTv3-100m-pre (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 22.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNTv3-100m-pre on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'NTv3-100m-pre', column 'cadd-snv' (ρ) |
| Configuration: NTv3-8m-pre (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 19.5 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceNTv3-8m-pre on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'NTv3-8m-pre', column 'cadd-snv' (ρ) |
| Configuration: PhyloGPN (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 23.6 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'PhyloGPN' with Eval. 'X', column 'cadd-snv' (ρ) |
| Configuration: PhyloGPN (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 9.8 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'PhyloGPN' with Eval. 'blank', column 'cadd-snv' (ρ) |
| Configuration: phyloP-100way (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 23.3 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcephyloP-100way on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'phyloP-100way', column 'cadd-snv' (ρ) |
| Configuration: phyloP-30way (zero-shot, GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 28.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcephyloP-30way on GUANinE cadd-snv lit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'phyloP-30way', column 'cadd-snv' (ρ) |
| Configuration: Sei (1% eval (evaluated with 1% of the training set), GUANinE v1.1) | Protocol: GUANinE v1.1 cadd-snv, Spearman rho x100 (Table 3) Dataset: GUANinE cadd-snv test set | 19.9 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcelit-genomics-20261011-guanine-protocol-cadd-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 3, row 'Sei', column 'cadd-snv' (ρ) |
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6 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Population Test set 1.04 M SNVs (Table 1) Context-only references | GUANinE v1.1 reveals complementarity of supervised and genomic language models Table 1 Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Source location Table 1 Context-only references | GUANinE v1.1 reveals complementarity of supervised and genomic language models Table 1 Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Split Test set (Test22 split; Table 1) Context-only references | GUANinE v1.1 reveals complementarity of supervised and genomic language models Table 1 Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Version GUANinE v1.1 Context-only references | GUANinE v1.1 reveals complementarity of supervised and genomic language models Table 1 Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Description Proxy deleteriousness of hg38 SNVs (CADD-style proxy labels; Nazaretyan et al. 2025). Context-only references | GUANinE v1.1 reveals complementarity of supervised and genomic language models Table 1 Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Name GUANinE cadd-snv test set Context-only references | GUANinE v1.1 reveals complementarity of supervised and genomic language models Table 1 Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: lit-genomics-20261011-guanine-data-cadd-snv