Independent validation set of the first Circulating Cell-free Genome Atlas substudy.
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9 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Negatives 362 Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Population 847 analysable participants: 485 with cancer and 362 without cancer (Table 1); Table 3 scores 464 cancers and 362 non-cancers; the difference is the 21 plasma cell neoplasms and leukaemias in each set, excluded because detection was restricted to solid cancers (STAR Methods; Table 1 footnote a) Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Positives 485 Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Scope note Case-control: participants with cancer were enrolled before treatment, and non-cancer participants were enrolled from the same centres or regions in a ratio of about 3 to 7. Participants were randomised to training and validation sets in sequencing batches; the first four batches were women only. All assays were run on contemporaneous blood samples from the same participants. Sequencing data are not public. Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Source location Figure 1; Table 1; Table 3 and its footnote a Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Total 847 Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Version CCGA (NCT02889978) substudy 1, validation set Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Description Independent validation set of the first Circulating Cell-free Genome Atlas substudy. Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
| Name CCGA substudy 1 validation set (847 analysable participants) Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Figure 1; Table 1; Table 3 and its footnote a Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py |
Release 2026-10-10-cbb3da59bc08 · Record review: source checked
Stable ID: ctdnajam-20261010-data-ccga1-validation