| Population 127 cancers, solid and haematologic Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: attributes.population Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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| Scope note A subset chosen by detection, so it is enriched for high tumour fraction. The Results name the three classifiers as WG methylation, SCNA and SNV-WBC; the Methods name them as WG methylation, SNV and SCNA-WBC. Origin classifiers were rerun with the plasma cell neoplasms and leukaemias that detection had excluded (STAR Methods). Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: attributes.scope_note Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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| Source location Results, cancer signal origin prediction; STAR Methods, CSO prediction Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: attributes.source_locator Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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| Total 127 Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: attributes.total Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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| Version CCGA (NCT02889978) substudy 1, validation set subset Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: attributes.version Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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| Description Validation-set cancers that the three representative detection classifiers all called positive at 98% specificity. Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: description Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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| Name CCGA substudy 1 validation cancers detected by all three representative classifiers (127) Context-only references | Evaluation of cell-free DNA approaches for multi-cancer early detection Original source ↗ Results, cancer signal origin prediction; STAR Methods, CSO prediction Version: Cancer Cell 40(12):1537-1549.e12, published 2022-12-12; publisher PDF (1-s2.0-S153561082200513X-main.pdf) as deposited by the Francis Crick Institute on figshare, 10.25418/crick.21731870.v1 Retrieved: 2026-10-10T06:05:17Z | not individually reviewed No individual claim review recorded Audit detailsField: name Source artifact SHA-256: 5159294dd203d511dd437837a34555b276e14e0edf615bcb58bae5d9a1246d9a Hash scope: pdftotext -layout text layer, parsed by extract/extract_ctdna_jamshidi.py Inspected artifact |
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