PROVEAN | configuration

Overview

Fitness prediction model evaluated by the ProteinGym authors under their harness.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

3 evaluations · 4 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: PROVEAN	Task: ProteinGym ZS-INDEL-AUC: Zero-shot indels, all assays, AUC Dataset subset: ProteinGym indel DMS assays (ProteinGym split)	0.725 auc fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source PROVEAN on ProteinGym ZS-INDEL-AUC: Zero-shot indels, all assays, AUC Zero-shot scoring of insertion and deletion assays, split by how the test sequences were generated. Aggregation: Not reported ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 4, row(PROVEAN), column(Zero-shot indels, all assays, AUC)
Configuration: PROVEAN	Task: ProteinGym ZS-INDEL-SPEARMAN-ALL: Zero-shot indels, all assays, Spearman Dataset subset: ProteinGym indel DMS assays (ProteinGym split)	0.347 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source PROVEAN on ProteinGym ZS-INDEL-SPEARMAN-ALL: Zero-shot indels, all assays, Spearman Zero-shot scoring of insertion and deletion assays, split by how the test sequences were generated. Aggregation: Not reported ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 4, row(PROVEAN), column(Zero-shot indels, all assays, Spearman)
Configuration: PROVEAN	Task: ProteinGym ZS-INDEL-SPEARMAN-DESIGNED: Zero-shot indels, designed or natural assays, Spearman Dataset subset: ProteinGym indel DMS assays (ProteinGym split)	0.585 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source PROVEAN on ProteinGym ZS-INDEL-SPEARMAN-DESIGNED: Zero-shot indels, designed or natural assays, Spearman Zero-shot scoring of insertion and deletion assays, split by how the test sequences were generated. Aggregation: Not reported ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 4, row(PROVEAN), column(Zero-shot indels, designed or natural assays, Spearman)
Configuration: PROVEAN	Task: ProteinGym ZS-INDEL-SPEARMAN-LIBRARY: Zero-shot indels, library assays, Spearman Dataset subset: ProteinGym indel DMS assays (ProteinGym split)	0.306 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source PROVEAN on ProteinGym ZS-INDEL-SPEARMAN-LIBRARY: Zero-shot indels, library assays, Spearman Zero-shot scoring of insertion and deletion assays, split by how the test sequences were generated. Aggregation: Not reported ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · Table 4, row(PROVEAN), column(Zero-shot indels, library assays, Spearman)

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