Configuration

Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)

DNAscope (short reads) pipeline; outputs SNP, indel and CNV.

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

1 evaluation · 7 results. Different protocols are not a single leaderboard.

Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) · Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)

Sorted by Compute cost (Azure on-demand price, FASTQ to VCF; 30x Illumina) (lower is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Compute cost (Azure on-demand price, FASTQ to VCF; 30x Illumina)	Compute cost (Azure spot price, FASTQ to VCF; 30x Illumina)	CPU time (total, FASTQ to VCF; 30x Illumina)	Runtime (alignment stage; 30x Illumina)	Runtime (preprocessing stage; 30x Illumina)	Runtime (total, FASTQ to VCF; 30x Illumina)	Runtime (variant calling stage; 30x Illumina)
Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)Evaluation	1.1	0.11	37.8	9.7	1.4	18.9	7.8

All 7 result rows with coverage, uncertainty and sources

Filter evaluations

Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	9.7 Runtime (alignment stage; 30x Illumina) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Alignment (min)', column 'DNAscope (short reads)'
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	37.8 CPU time (total, FASTQ to VCF; 30x Illumina) hour · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Core-hours', column 'DNAscope (short reads)'
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	1.1 Compute cost (Azure on-demand price, FASTQ to VCF; 30x Illumina) us-dollar · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'On-demand ($)', column 'DNAscope (short reads)'
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	1.4 Runtime (preprocessing stage; 30x Illumina) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Preprocessing (min)', column 'DNAscope (short reads)'
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	0.11 Compute cost (Azure spot price, FASTQ to VCF; 30x Illumina) us-dollar · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Spot ($)', column 'DNAscope (short reads)'
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	18.9 Runtime (total, FASTQ to VCF; 30x Illumina) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Total runtime (min)', column 'DNAscope (short reads)'
Configuration: Sentieon DNAscope (short reads) on Azure HB120rs v3 (Hu et al. 2026)	Protocol: FASTQ-to-VCF runtime, core-hours and Azure cost of three Sentieon DNAscope pipelines on one 120-vCPU instance (Hu et al. 2026 Table 2) Dataset: 30x Illumina WGS input for DNAscope (short reads) (Hu et al. 2026 Table 2)	7.8 Runtime (variant calling stage; 30x Illumina) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026) model-execution-20261011-protocol-hu2026-dnascope-azure-compute Aggregation: Not reported A novel and accelerated method for integrated alignment and variant calling from short and long reads · Table 2, row 'Variant calling (min)', column 'DNAscope (short reads)'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

Use this configuration

How it works, versions and access

Strengths, limitations and unresolved questions

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

0 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance

No evidence rows match these filters. Choose another scope or clear the search.

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release history

A novel and accelerated method for integrated alignment and variant calling from short and long reads · Original source · Frontiers in Bioinformatics 5:1691056, published 2026-01-05; PMC12813096 full-text XML

Download this release (gzip)

Technical metadata and extraction receipts

Stable ID: model-execution-20261011-config-hu2026-dnascope-short-read-azure-hb120rs-v3

areas: dna-genomes
contexts: clinical_research
method types: conventional_pipeline
reported name: DNAscope (short reads)
foundation model eligible: false
hardware: description: Azure Standard HB120rs v3: 120 vCPUs, 456 GiB memory, 512 GB premium SSD (Table 2 caption)
protocol: DNAscope (short reads) pipeline from FASTQ; outputs SNP, indel and CNV
access reuse: Commercial licensed software
source locator: Table 2 caption and column 'DNAscope (short reads)'
missing metadata: version: reason: unreported; note: Sentieon release not stated for Table 2

Related records

configuration of: Sentieon DNAscope
system: DNAscope (short reads) compute benchmark on Azure (Hu et al. 2026)

Suggest a correction