Virus profiler benchmark against a shared Virus Pathogen Database (Tisza et al. 2026)
EsViritu, Kraken2, Centrifuger, Metabuli and Sylph on positive controls, pathogen-free negative controls and mutated mock communities, all querying the same database.
Results are recorded on the linked protocols, tasks or configurations listed below. Their settings and evaluations are kept separate.
Overview
An explanatory profile has not yet been reviewed for this record.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Results on linked records
This benchmark has no results of its own in this release. 3 linked records have results. They are not assigned to the underlying benchmark: each record keeps its own settings and evaluations, and its scores are on its own page.
- Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Protocol · part of this benchmark · 5 evaluations · 75 results
- False positives in seven pathogen-free libraries (Tisza et al. 2026 Table S6) Protocol · part of this benchmark · 5 evaluations · 20 results
- Positive-control virus detection by read depth (Tisza et al. 2026 Table S2) Protocol · part of this benchmark · 5 evaluations · 10 results
Methods and evaluation design
Procedure, tasks and evaluated configurations
Baseline coverage
Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.
0 of 6 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.
Baseline status by linked protocol
- Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) · 0/2 roles measured
- False positives in seven pathogen-free libraries (Tisza et al. 2026 Table S6) · 0/2 roles measured
- Positive-control virus detection by read depth (Tisza et al. 2026 Table S2) · 0/2 roles measured
Protocol coverage CSV (gzip) · Model evaluation matrix (gzip) · Source table (gzip) · Release and checksums (gzip)
Coverage is derived from release 2026-10-22-1b7cf027e4f6. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.
Run instructions
No runnable recipe has been reviewed for this benchmark. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.
Strengths, limitations and unresolved questions
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
0 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|
No evidence rows match these filters. Choose another scope or clear the search.
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes · Original source · bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML
Technical metadata and extraction receipts
Stable ID: rna-pathogen-20261011-tisza2026-benchmark-virus-profilers
- areas
- microbes-communities
- contexts
- research
- entity level
- suite
- version
- bioRxiv v1, Supplemental Tables S1-S25
- task
- Detect and profile vertebrate, plant and other pathogen viruses from metagenomic reads
- source locator
- Results; Methods 'Tools and parameters', 'Positive controls', 'Negative controls', 'Mock communities'
- scope note
- Only Supplemental Tables S2, S6 and S9 (headline settings) were extracted; per-sample and parameter-sweep tables (S5, S10, S22, S24), regression terms (S1, S3, S11, S12), statistical tests and timing (S15) were not.
- limitations
- Benchmark built and run by the developers of EsViritu.; All data are synthetic or pathogen-free libraries; no clinical specimen with a reference test.
Related records
- subject: reference_database: rna-pathogen-20261011-tisza2026-benchmark-virus-profilers
- part of: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9)
- part of: False positives in seven pathogen-free libraries (Tisza et al. 2026 Table S6)
- part of: Positive-control virus detection by read depth (Tisza et al. 2026 Table S2)