Scoped author-reported evaluation; read protocol and cohort limits before comparing. Preprint result; not peer reviewed.
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Release 2026-10-06-fea06f63ac0e · Evidence verified: Not verified
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1 evaluation · 2 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: HECTOR automated classifier (ENIGMA V1.2 specification) | Protocol: HECTOR vs. ENIGMA Evidence Repository (eRepo) agreement Dataset: ENIGMA Evidence Repository (eRepo) BRCA1/BRCA2 reference set | 75.5% (108/143) classification_agreement_rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceHECTOR eRepo concordance evaluation Not reported Aggregation: Not reported HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications · Results, "Evidence Repository": "At the classification level, HECTOR agreed with the ENIGMA VCEP classification for 108 of the 143 variants (75.5%)." |
| Configuration: HECTOR automated classifier (ENIGMA V1.2 specification) | Protocol: HECTOR vs. ENIGMA Evidence Repository (eRepo) agreement Dataset: ENIGMA Evidence Repository (eRepo) BRCA1/BRCA2 reference set | 78.9% (326/413) criteria_code_agreement_rate percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceHECTOR eRepo concordance evaluation Not reported Aggregation: Not reported HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications · Results, "Evidence Repository": "...the ENIGMA VCEP applied 413 evidence codes, of which HECTOR reproduced 326 (78.9%) at the identical code and strength (Figure 1)." |
Source checking is not independent reproduction. Release 2026-10-06-fea06f63ac0e.
Not reported
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No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
18 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.comparison.adaptation Not reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.aggregation Not reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.budget Not reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.dataset_version Not reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.inputs Not reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.metric_implementation Source-defined endpoint; see result source_locator Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.population ENIGMA Evidence Repository (eRepo) 143-variant reference set Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.protocol_id uc-clinical-20261005-hector-erepo-protocol Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.comparison.split Not reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.origin author_reported Context-only references | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository" Version: medRxiv preprint v1, posted 2026-07-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
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Release 2026-10-06-fea06f63ac0e · Record review: source checked
Stable ID: uc-clinical-20261005-hector-erepo-evaluation