75.5% (108/143) classification_agreement_rate
HECTOR eRepo: classification_agreement_rate
- Tested configuration
- HECTOR automated classifier (ENIGMA V1.2 specification)
- Protocol
- HECTOR vs. ENIGMA Evidence Repository (eRepo) agreement
- Dataset
- ENIGMA Evidence Repository (eRepo) BRCA1/BRCA2 reference set
- Procedure
- Not reported
- Evaluation
- HECTOR eRepo concordance evaluation
- Coverage
- scored: unreported; eligible: unreported
- Uncertainty
- Not reported
- Evidence
- Author-reported evaluation · source checkedHECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications · Results, "Evidence Repository": "At the classification level, HECTOR agreed with the ENIGMA VCEP classification for 108 of the 143 variants (75.5%)."
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.
Reproduction
- Split
- Not reported
- Adaptation
- Not reported
- Scoring implementation
- Source-defined endpoint; see result source_locator
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 75.5% (108/143) Individual claims | HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications Results, "Evidence Repository": "At the classification level, HECTOR agreed with the ENIGMA VCEP classification for 108 of the 143 variants (75.5%)." Version: medRxiv preprint v1, posted 2026-07-06 | source checked automated source review · 2026-10-06 author reported Audit detailsTranscription from inspected primary source. No execution, independent replication or human scientific review. Corrected 2026-10-06: the eRepo comparator was re-verified live against the preprint and relabelled from "ClinVar expert-panel" to the ENIGMA VCEP's expert-curated classifications and evidence-code assignments in the ClinGen Evidence Repository (eRepo); no numeric values changed. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
View linked audit checks and correction history
Release 2026-10-06-fea06f63ac0e · Record review: source checked
1 source records and release history
- HECTOR: A Web-Based Tool for Automated BRCA1/BRCA2 Variant Classification Under the ClinGen ENIGMA Specifications · Original source · medRxiv preprint v1, posted 2026-07-06
Technical metadata and extraction receipts
Stable ID: uc-clinical-20261005-hector-erepo-classification-agreement
- areas
- dna-genomes
- contexts
- clinical_research
- metric
- classification_agreement_rate
- unit
- percent
- printed value
- 75.5% (108/143)
- numeric value
- 75.5
- metric direction
- higher
- uncertainty
- Not reported
- numerator
- 108
- denominator
- 143
- source locator
- Results, "Evidence Repository": "At the classification level, HECTOR agreed with the ENIGMA VCEP classification for 108 of the 143 variants (75.5%)."
- review
- method: automated_source_review; reviewer: Claude Sonnet clinical coverage worker (research-evidence intake); date: 2026-10-06; note: Transcription from inspected primary source. No execution, independent replication or human scientific review. Corrected 2026-10-06: the eRepo comparator was re-verified live against the preprint and relabelled from "ClinVar expert-panel" to the ENIGMA VCEP's expert-curated classifications and evidence-code assignments in the ClinGen Evidence Repository (eRepo); no numeric values changed.; source id: uc-clinical-20261005-source-hector-preprint
- missing metadata
- uncertainty: not reported for this endpoint
Related records
- evaluation: HECTOR eRepo concordance evaluation