Published developer benchmark; transcribed, not reproduced.
1 evaluation · 15 results. Different protocols are not a single leaderboard.
Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) · Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026)
Sorted by Bray curtis dissimilarity (RPM-based abundance profile; mean over mock communities; ANI-capped truth) (lower is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Bray curtis dissimilarity (RPM-based abundance profile; mean over mock communities; ANI-capped truth) | Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank family, strict truth) | Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank genus, strict truth) | Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank species, strict truth) | Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank subspecies, strict truth) | F1 (taxon detection; mean over mock communities; ANI-capped truth) | F1 (taxon detection; mean over six mock communities; rank family, strict truth) | F1 (taxon detection; mean over six mock communities; rank genus, strict truth) | F1 (taxon detection; mean over six mock communities; rank species, strict truth) | F1 (taxon detection; mean over six mock communities; rank subspecies, strict truth) | Pearson (abundance profile against truth; mean over mock communities; ANI-capped truth) | Pearson (abundance profile against truth; mean over six mock communities; rank family, strict truth) | Pearson (abundance profile against truth; mean over six mock communities; rank genus, strict truth) | Pearson (abundance profile against truth; mean over six mock communities; rank species, strict truth) | Pearson (abundance profile against truth; mean over six mock communities; rank subspecies, strict truth) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kraken2 v2.17.1, headline setting (Tisza et al. 2026)Evaluation | 0.59 | 0.572 | 0.557 | 0.598 | 0.594 | 0.54 | 0.754 | 0.682 | 0.632 | 0.612 | 0.353 | 0.384 | 0.406 | 0.365 | 0.37 |
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.59 Bray curtis dissimilarity (RPM-based abundance profile; mean over mock communities; ANI-capped truth) unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 26 (base_tool 'Kraken2', rank 'ani_capped', truth_mode 'capped'), column 'bray_curtis' (cell E26) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.54 F1 (taxon detection; mean over mock communities; ANI-capped truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 26 (base_tool 'Kraken2', rank 'ani_capped', truth_mode 'capped'), column 'F1' (cell D26) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.353 Pearson (abundance profile against truth; mean over mock communities; ANI-capped truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 26 (base_tool 'Kraken2', rank 'ani_capped', truth_mode 'capped'), column 'pearson' (cell F26) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.572 Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank family, strict truth) unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 6 (base_tool 'Kraken2', rank 'family', truth_mode 'strict'), column 'bray_curtis' (cell E6) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.754 F1 (taxon detection; mean over six mock communities; rank family, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 6 (base_tool 'Kraken2', rank 'family', truth_mode 'strict'), column 'F1' (cell D6) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.384 Pearson (abundance profile against truth; mean over six mock communities; rank family, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 6 (base_tool 'Kraken2', rank 'family', truth_mode 'strict'), column 'pearson' (cell F6) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.557 Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank genus, strict truth) unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 11 (base_tool 'Kraken2', rank 'genus', truth_mode 'strict'), column 'bray_curtis' (cell E11) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.682 F1 (taxon detection; mean over six mock communities; rank genus, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 11 (base_tool 'Kraken2', rank 'genus', truth_mode 'strict'), column 'F1' (cell D11) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.406 Pearson (abundance profile against truth; mean over six mock communities; rank genus, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 11 (base_tool 'Kraken2', rank 'genus', truth_mode 'strict'), column 'pearson' (cell F11) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.598 Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank species, strict truth) unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 16 (base_tool 'Kraken2', rank 'species', truth_mode 'strict'), column 'bray_curtis' (cell E16) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.632 F1 (taxon detection; mean over six mock communities; rank species, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 16 (base_tool 'Kraken2', rank 'species', truth_mode 'strict'), column 'F1' (cell D16) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.365 Pearson (abundance profile against truth; mean over six mock communities; rank species, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 16 (base_tool 'Kraken2', rank 'species', truth_mode 'strict'), column 'pearson' (cell F16) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.594 Bray curtis dissimilarity (RPM-based abundance profile; mean over six mock communities; rank subspecies, strict truth) unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 21 (base_tool 'Kraken2', rank 'subspecies', truth_mode 'strict'), column 'bray_curtis' (cell E21) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.612 F1 (taxon detection; mean over six mock communities; rank subspecies, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 21 (base_tool 'Kraken2', rank 'subspecies', truth_mode 'strict'), column 'F1' (cell D21) |
| Configuration: Kraken2 v2.17.1, headline setting (Tisza et al. 2026) | Protocol: Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9) Dataset: Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) | 0.37 Pearson (abundance profile against truth; mean over six mock communities; rank subspecies, strict truth) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourcerna-pathogen-20261011-tisza2026-protocol-mock Aggregation: Not reported Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) · Supplemental Table S9, row 21 (base_tool 'Kraken2', rank 'subspecies', truth_mode 'strict'), column 'pearson' (cell F21) |
Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified
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Mutated virus mock-community profiling against ground truth (Tisza et al. 2026 Table S9)
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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
38 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation Headline setting: confidence 0.5, minimum-hit-group 2 Context-only references | EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: adaptation Headline setting: confidence 0.5, minimum-hit-group 2 Context-only references | Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Mean over six communities Context-only references | EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Mean over six communities Context-only references | Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) Context-only references | EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version Six mutated virus mock communities with bacterial and human background (Tisza et al. 2026) Context-only references | Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: inputs Synthetic NovaSeq read pairs (InSilicoSeq) Context-only references | EsViritu is a sensitive and specific profiler for viral pathogen detection and genome recovery in metagenomes Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1, posted 2026-09-30; JATS XML | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: inputs Synthetic NovaSeq read pairs (InSilicoSeq) Context-only references | Tisza et al. 2026 Supplemental Tables S1-S25 (bioRxiv media-1.xlsx) Supplemental Table S9, rows base_tool 'Kraken2' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv 10.64898/2026.09.29.755457 v1 supplementary file DC1 (755457_file02.xlsx) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: rna-pathogen-20261011-tisza2026-eval-mock-kraken2