| Method: CNN | Task: FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Dataset subset: FLIP Random sampled splits, AAV split (FLIP split) | 0.92 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceCNN on FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Trained on the split's training set with ten percent held out for validation, scored on its test set. The authors report these separately and call them optimistic: a random split of a mutational landscape leaks close relatives between train and test. Aggregation: Not reported flip primary benchmark evidence · Table 7, row(CNN), column(AAV) |
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| Configuration: ESM-1b (per AA) | Task: FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Dataset subset: FLIP Random sampled splits, AAV split (FLIP split) | 0.9 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1b (per AA) on FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Trained on the split's training set with ten percent held out for validation, scored on its test set. The authors report these separately and call them optimistic: a random split of a mutational landscape leaks close relatives between train and test. Aggregation: Not reported flip primary benchmark evidence · Table 7, row(ESM-1b (per AA)), column(AAV) |
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| Configuration: ESM-1v (per AA) | Task: FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Dataset subset: FLIP Random sampled splits, AAV split (FLIP split) | 0.92 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-1v (per AA) on FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Trained on the split's training set with ten percent held out for validation, scored on its test set. The authors report these separately and call them optimistic: a random split of a mutational landscape leaks close relatives between train and test. Aggregation: Not reported flip primary benchmark evidence · Table 7, row(ESM-1v (per AA)), column(AAV) |
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| Configuration: ESM-untrained (per AA) | Task: FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Dataset subset: FLIP Random sampled splits, AAV split (FLIP split) | 0.78 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-untrained (per AA) on FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Trained on the split's training set with ten percent held out for validation, scored on its test set. The authors report these separately and call them optimistic: a random split of a mutational landscape leaks close relatives between train and test. Aggregation: Not reported flip primary benchmark evidence · Table 7, row(ESM-untrained (per AA)), column(AAV) |
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| Method: Ridge | Task: FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Dataset subset: FLIP Random sampled splits, AAV split (FLIP split) | 0.83 spearman correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceRidge on FLIP RANDOM-SAMPLED-SPLITS-AAV: Random sampled splits fitness prediction, AAV split Trained on the split's training set with ten percent held out for validation, scored on its test set. The authors report these separately and call them optimistic: a random split of a mutational landscape leaks close relatives between train and test. Aggregation: Not reported flip primary benchmark evidence · Table 7, row(Ridge), column(AAV) |
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