10,356 labeled enhancer–gene perturbation pairs, 471 positive and 9,885 negative; not allele-editing or causal-disease ground truth.
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Release 2026-09-30-e37e3ab1284d · Evidence verified: Not verified
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6 evaluations · 10 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Activity-by-Contact (ABC) — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.612 (0.567–0.656) auprc fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.567; upper: 0.656; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Results, Figure 2 comparison paragraph, Activity-by-Contact (ABC), auprc |
| Configuration: MPRabc — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.707 (0.663–0.746) auprc fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.663; upper: 0.746; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, MPRabc, auprc |
| Configuration: MPRabc — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.680 (0.637–0.724) precision-at-70-recall fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.637; upper: 0.724; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, MPRabc, precision-at-70-recall |
| Configuration: MPRabc megamap Hi-C — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.69 auprc fraction · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Results, Figure 2 comparison paragraph, MPRabc megamap Hi-C, auprc |
| Configuration: MPRabc (MPRALegNet only; no Sei) — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.686 (0.642–0.728) auprc fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.642; upper: 0.728; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, MPRabc (MPRALegNet only; no Sei), auprc |
| Configuration: MPRabc (MPRALegNet only; no Sei) — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.655 (0.610–0.695) precision-at-70-recall fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.610; upper: 0.695; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, MPRabc (MPRALegNet only; no Sei), precision-at-70-recall |
| Configuration: ENCODE-rE2G — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.634 (0.587–0.684) auprc fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.587; upper: 0.684; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, ENCODE-rE2G, auprc |
| Configuration: ENCODE-rE2G — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.543 (0.501–0.583) precision-at-70-recall fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.501; upper: 0.583; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, ENCODE-rE2G, precision-at-70-recall |
| Configuration: MPRabc (Sei only; no MPRALegNet) — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.707 (0.664–0.746) auprc fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.664; upper: 0.746; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, MPRabc (Sei only; no MPRALegNet), auprc |
| Configuration: MPRabc (Sei only; no MPRALegNet) — K562 published comparison | Protocol: MPRabc K562 CRISPRi enhancer–gene evaluation Dataset: MPRabc K562 CRISPRi benchmark | 0.678 (0.634–0.720) precision-at-70-recall fraction · higher Uncertainty: type: bootstrap_percentile_confidence_interval; level: 0.95; lower: 0.634; upper: 0.720; replicates: 10000 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions · Table 3, MPRabc (Sei only; no MPRALegNet), precision-at-70-recall |
Source checking is not independent reproduction. Release 2026-09-30-e37e3ab1284d.
A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
5 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.negatives 9885 Context-only references | MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions No field-specific location recorded Version: PMC13232518 published article XML retrieved 2026-09-30 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.positives 471 Context-only references | MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions No field-specific location recorded Version: PMC13232518 published article XML retrieved 2026-09-30 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.total 10356 Context-only references | MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions No field-specific location recorded Version: PMC13232518 published article XML retrieved 2026-09-30 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| description 10,356 labeled enhancer–gene perturbation pairs, 471 positive and 9,885 negative; not allele-editing or causal-disease ground truth. Context-only references | MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions No field-specific location recorded Version: PMC13232518 published article XML retrieved 2026-09-30 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| name MPRabc K562 CRISPRi benchmark Context-only references | MPRA-informed modeling improves context-specific enhancer–gene regulatory interactions No field-specific location recorded Version: PMC13232518 published article XML retrieved 2026-09-30 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
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Release 2026-09-30-e37e3ab1284d · Record review: source checked
Stable ID: ucc-research-data-mprabc-k562-crispri