Distance to TSS (Gschwind et al. 2026)
Distance to TSS (Gschwind et al. 2026) as evaluated in the cited comparison.
Overview
Distance to TSS (Gschwind et al. 2026) as evaluated in the cited comparison.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
2 evaluations · 6 results. Different protocols are not a single leaderboard.
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Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Distance to TSS (Gschwind et al. 2026) | Protocol: Held-out CRISPR enhancer-gene benchmark, weighted metrics, five cell types (Gschwind et al. 2026 Supplementary Table 3) Dataset: Held-out CRISPR enhancer-gene pairs in five cell types (Gschwind et al. 2026) | 0.363 auprc fraction · higher Uncertainty: 95% CI 0.281241216228264 to 0.437896240213437 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceDistance to TSS on held-out CRISPR pairs, five cell types regulatory-variant-20261009-protocol-gschwind2026-heldout-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 6 (D6:F6); Dataset 'Held-out', Predictor 'Distance to TSS', metric 'Weighted AUPRC' |
| Configuration: Distance to TSS (Gschwind et al. 2026) | Protocol: Held-out CRISPR enhancer-gene benchmark, weighted metrics, five cell types (Gschwind et al. 2026 Supplementary Table 3) Dataset: Held-out CRISPR enhancer-gene pairs in five cell types (Gschwind et al. 2026) | 0.245 precision fraction · higher Uncertainty: 95% CI 0.202048095028741 to 0.288268461392336 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceDistance to TSS on held-out CRISPR pairs, five cell types regulatory-variant-20261009-protocol-gschwind2026-heldout-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 12 (D12:F12); Dataset 'Held-out', Predictor 'Distance to TSS', metric 'Weighted precision at threshold' |
| Configuration: Distance to TSS (Gschwind et al. 2026) | Protocol: Held-out CRISPR enhancer-gene benchmark, weighted metrics, five cell types (Gschwind et al. 2026 Supplementary Table 3) Dataset: Held-out CRISPR enhancer-gene pairs in five cell types (Gschwind et al. 2026) | 0.584 recall fraction · higher Uncertainty: 95% CI 0.511553237372335 to 0.655007748643397 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceDistance to TSS on held-out CRISPR pairs, five cell types regulatory-variant-20261009-protocol-gschwind2026-heldout-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 18 (D18:F18); Dataset 'Held-out', Predictor 'Distance to TSS', metric 'Weighted recall at threshold' |
| Configuration: Distance to TSS (Gschwind et al. 2026) | Protocol: Combined K562 CRISPR training pairs, weighted metrics (Gschwind et al. 2026 Supplementary Table 3) Dataset: MPRabc K562 CRISPRi benchmark | 0.435 auprc fraction · higher Uncertainty: 95% CI 0.381294301517761 to 0.487138690854213 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceDistance to TSS on combined K562 CRISPR training pairs regulatory-variant-20261009-protocol-gschwind2026-k562-training-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 24 (D24:F24); Dataset 'Combined K562 (training)', Predictor 'Distance to TSS', metric 'Weighted AUPRC' |
| Configuration: Distance to TSS (Gschwind et al. 2026) | Protocol: Combined K562 CRISPR training pairs, weighted metrics (Gschwind et al. 2026 Supplementary Table 3) Dataset: MPRabc K562 CRISPRi benchmark | 0.291 precision fraction · higher Uncertainty: 95% CI 0.262423650910323 to 0.319101531577943 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceDistance to TSS on combined K562 CRISPR training pairs regulatory-variant-20261009-protocol-gschwind2026-k562-training-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 30 (D30:F30); Dataset 'Combined K562 (training)', Predictor 'Distance to TSS', metric 'Weighted precision at threshold' |
| Configuration: Distance to TSS (Gschwind et al. 2026) | Protocol: Combined K562 CRISPR training pairs, weighted metrics (Gschwind et al. 2026 Supplementary Table 3) Dataset: MPRabc K562 CRISPRi benchmark | 0.755 recall fraction · higher Uncertainty: 95% CI 0.712739109282484 to 0.795269968200388 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceDistance to TSS on combined K562 CRISPR training pairs regulatory-variant-20261009-protocol-gschwind2026-k562-training-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 36 (D36:F36); Dataset 'Combined K562 (training)', Predictor 'Distance to TSS', metric 'Weighted recall at threshold' |
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Evidence
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Sources and history
Release 2026-10-10-7fcc3e48a123 · Record review: source checked
2 source records and release history
- An encyclopedia of human enhancer-gene regulatory interactions · Original source · Nature 657(8130):179, published online 2026-07-15; PMC13471189 full-text XML
- Gschwind et al. 2026, Supplementary Table 3 · Original source · Supplementary_Table_3.xlsx in 41586_2026_10781_MOESM3_ESM.zip (folder 2023-11-20318B-s3) inside the Europe PMC supplementaryFiles zip
Technical metadata and extraction receipts
Stable ID: regulatory-variant-20261009-config-gschwind2026-distance-to-tss
- areas
- dna-genomes
- contexts
- research
- method types
- conventional_pipeline
- reported name
- Distance to TSS (Gschwind et al. 2026)
- foundation model eligible
- false
- missing metadata
- version: reason: unreported; note: Predictor version not printed in Supplementary Table 3; parameters are in Supplementary Table 1 (not read)
- source locator
- Supplementary Table 3 'Held-out benchmarks', predictor 'Distance to TSS'
Related records
- configuration of: Distance to TSS baseline
- system: Distance to TSS on held-out CRISPR pairs, five cell types
- system: Distance to TSS on combined K562 CRISPR training pairs