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Correlation_E-P DNase-seq signal (Gschwind et al. 2026)

Correlation_E-P DNase-seq signal (Gschwind et al. 2026) as evaluated in the cited comparison.

Overview

Correlation_E-P DNase-seq signal (Gschwind et al. 2026) as evaluated in the cited comparison.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

2 evaluations · 6 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)	Protocol: Held-out CRISPR enhancer-gene benchmark, weighted metrics, five cell types (Gschwind et al. 2026 Supplementary Table 3) Dataset: Held-out CRISPR enhancer-gene pairs in five cell types (Gschwind et al. 2026)	0.211 auprc fraction · higher Uncertainty: 95% CI 0.155299843477219 to 0.267454116811189 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Correlation_E-P DNase-seq signal on held-out CRISPR pairs, five cell types regulatory-variant-20261009-protocol-gschwind2026-heldout-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 7 (D7:F7); Dataset 'Held-out', Predictor 'Correlation_E-P DNase-seq signal', metric 'Weighted AUPRC'
Configuration: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)	Protocol: Held-out CRISPR enhancer-gene benchmark, weighted metrics, five cell types (Gschwind et al. 2026 Supplementary Table 3) Dataset: Held-out CRISPR enhancer-gene pairs in five cell types (Gschwind et al. 2026)	0.112 precision fraction · higher Uncertainty: 95% CI 0.09490444 to 0.130640831462308 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Correlation_E-P DNase-seq signal on held-out CRISPR pairs, five cell types regulatory-variant-20261009-protocol-gschwind2026-heldout-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 13 (D13:F13); Dataset 'Held-out', Predictor 'Correlation_E-P DNase-seq signal', metric 'Weighted precision at threshold'
Configuration: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)	Protocol: Held-out CRISPR enhancer-gene benchmark, weighted metrics, five cell types (Gschwind et al. 2026 Supplementary Table 3) Dataset: Held-out CRISPR enhancer-gene pairs in five cell types (Gschwind et al. 2026)	0.737 recall fraction · higher Uncertainty: 95% CI 0.669820594780111 to 0.79971637 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Correlation_E-P DNase-seq signal on held-out CRISPR pairs, five cell types regulatory-variant-20261009-protocol-gschwind2026-heldout-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 19 (D19:F19); Dataset 'Held-out', Predictor 'Correlation_E-P DNase-seq signal', metric 'Weighted recall at threshold'
Configuration: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)	Protocol: Combined K562 CRISPR training pairs, weighted metrics (Gschwind et al. 2026 Supplementary Table 3) Dataset: MPRabc K562 CRISPRi benchmark	0.188 auprc fraction · higher Uncertainty: 95% CI 0.153700202257717 to 0.226562560550906 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Correlation_E-P DNase-seq signal on combined K562 CRISPR training pairs regulatory-variant-20261009-protocol-gschwind2026-k562-training-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 25 (D25:F25); Dataset 'Combined K562 (training)', Predictor 'Correlation_E-P DNase-seq signal', metric 'Weighted AUPRC'
Configuration: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)	Protocol: Combined K562 CRISPR training pairs, weighted metrics (Gschwind et al. 2026 Supplementary Table 3) Dataset: MPRabc K562 CRISPRi benchmark	0.0846 precision fraction · higher Uncertainty: 95% CI 0.0748657 to 0.09422633 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Correlation_E-P DNase-seq signal on combined K562 CRISPR training pairs regulatory-variant-20261009-protocol-gschwind2026-k562-training-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 31 (D31:F31); Dataset 'Combined K562 (training)', Predictor 'Correlation_E-P DNase-seq signal', metric 'Weighted precision at threshold'
Configuration: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)	Protocol: Combined K562 CRISPR training pairs, weighted metrics (Gschwind et al. 2026 Supplementary Table 3) Dataset: MPRabc K562 CRISPRi benchmark	0.71 recall fraction · higher Uncertainty: 95% CI 0.663954244027132 to 0.754126177061213 Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source Correlation_E-P DNase-seq signal on combined K562 CRISPR training pairs regulatory-variant-20261009-protocol-gschwind2026-k562-training-weighted Aggregation: Not reported An encyclopedia of human enhancer-gene regulatory interactions; Gschwind et al. 2026, Supplementary Table 3 · Supplementary Table 3 'Held-out benchmarks', row 37 (D37:F37); Dataset 'Combined K562 (training)', Predictor 'Correlation_E-P DNase-seq signal', metric 'Weighted recall at threshold'

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Sources and history

Release 2026-10-10-6e93f504adfc · Record review: source checked

2 source records and release history

An encyclopedia of human enhancer-gene regulatory interactions · Original source · Nature 657(8130):179, published online 2026-07-15; PMC13471189 full-text XML
Gschwind et al. 2026, Supplementary Table 3 · Original source · Supplementary_Table_3.xlsx in 41586_2026_10781_MOESM3_ESM.zip (folder 2023-11-20318B-s3) inside the Europe PMC supplementaryFiles zip

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Technical metadata and extraction receipts

Stable ID: regulatory-variant-20261009-config-gschwind2026-ep-dnase-correlation

areas: dna-genomes
contexts: research
method types: conventional_pipeline
reported name: Correlation_E-P DNase-seq signal (Gschwind et al. 2026)
foundation model eligible: false
missing metadata: version: reason: unreported; note: Predictor version not printed in Supplementary Table 3; parameters are in Supplementary Table 1 (not read)
source locator: Supplementary Table 3 'Held-out benchmarks', predictor 'Correlation_E-P DNase-seq signal'

Related records

configuration of: Element-promoter DNase-seq correlation baseline
system: Correlation_E-P DNase-seq signal on held-out CRISPR pairs, five cell types
system: Correlation_E-P DNase-seq signal on combined K562 CRISPR training pairs

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