Previously analysed families; variant calling eligibility conditions the recovery denominator.
These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.
Release 2026-09-30-e37e3ab1284d · Evidence verified: Not verified
Exact outcomes, predictions, identifiers and evaluator are connected.
Missing or unresolved evidence
Verified: Not verified
Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.
Missing or unresolved evidence
Verified: Not verified
A pinned recipe describes the inputs, environment and resource requirements.
Missing or unresolved evidence
Verified: Not verified
Separate data and exposure records support an independent test.
Missing or unresolved evidence
Verified: Not verified
Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.
No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.
2 evaluations · 10 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Talos default filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 519 candidate_variants count · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: total Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, default, Candidate variants |
| Configuration: Talos default filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 1.3 candidates_per_proband variants per proband · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: table ratio Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, default, Candidates per proband |
| Configuration: Talos default filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 11 candidates_per_recovered_diagnosis variants per diagnosis · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: table ratio Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, default, Candidates per diagnoses |
| Configuration: Talos default filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 47 recovered_known_diagnoses count · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, default, Diagnoses |
| Configuration: Talos default filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 87% known_diagnosis_recovery percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, default, Diagnoses (%) |
| Configuration: Talos strict phenotype-match filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 335 candidate_variants count · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: total Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, strict, Candidate variants |
| Configuration: Talos strict phenotype-match filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 0.9 candidates_per_proband variants per proband · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: table ratio Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, strict, Candidates per proband |
| Configuration: Talos strict phenotype-match filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 7.4 candidates_per_recovered_diagnosis variants per diagnosis · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: table ratio Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, strict, Candidates per diagnoses |
| Configuration: Talos strict phenotype-match filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 45 recovered_known_diagnoses count · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, strict, Diagnoses |
| Configuration: Talos strict phenotype-match filtering, 2026 study | Protocol: Talos diagnosis recovery and workload: RGP trio Dataset: Talos RGP trio evaluation cohort | 83% known_diagnosis_recovery percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNot reported Aggregation: Not reported Talos Table 1: complete evaluation cohort outcomes · Table 1, RGP trio, strict, Diagnoses (%) |
Source checking is not independent reproduction. Release 2026-09-30-e37e3ab1284d.
A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
6 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.known_detectable_diagnoses 54 Context-only references | Talos Table 1: complete evaluation cohort outcomes Table 1, RGP, trio, first two rows Version: Table 1 in final 2026 article | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.probands 390 Context-only references | Talos Table 1: complete evaluation cohort outcomes Table 1, RGP, trio, first two rows Version: Table 1 in final 2026 article | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.reuse_restrictions Study-level aggregates only; individual genomic data access not established Context-only references | Talos Table 1: complete evaluation cohort outcomes Table 1, RGP, trio, first two rows Version: Table 1 in final 2026 article | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.source_locator Table 1, RGP, trio, first two rows Context-only references | Talos Table 1: complete evaluation cohort outcomes Table 1, RGP, trio, first two rows Version: Table 1 in final 2026 article | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| description Previously analysed families; variant calling eligibility conditions the recovery denominator. Context-only references | Talos Table 1: complete evaluation cohort outcomes Table 1, RGP, trio, first two rows Version: Table 1 in final 2026 article | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| name Talos RGP trio evaluation cohort Context-only references | Talos Table 1: complete evaluation cohort outcomes Table 1, RGP, trio, first two rows Version: Table 1 in final 2026 article | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
View linked audit checks and correction history
Release 2026-09-30-e37e3ab1284d · Record review: source checked
Stable ID: uc-clinical-20260930-talos-rgp-trio-data