Configuration

NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)

H100 column of Supplementary Table S3.

Overview

H100 column of Supplementary Table S3.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

5 evaluations · 43 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	6.08 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12778', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	4.15 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12812', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	9.82 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12829', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	6.65 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12843', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	16.4 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12877', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14.6 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12878', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	20.1 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12889', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14.8 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12890', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	22.5 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12891', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	16.1 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), DeepVariant calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-dv Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12892', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: Parabricks DeepVariant v4.1.0-1 versus v4.3.0-1 on 8 H100 GPUs (Samarakoon et al. 2025 Table S4) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14.6 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Parabricks DV.v4.1.0-1 on 8 H100 GPUs (Samarakoon et al. 2025 Table S4) model-execution-20261009-protocol-samarakoon2025-dv-version-h100 Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S4, row 'NA12878', column 'Parabricks DV.v4.1.0-1' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: Parabricks DeepVariant v4.1.0-1 versus v4.3.0-1 on 8 H100 GPUs (Samarakoon et al. 2025 Table S4) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14.8 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Parabricks DV.v4.1.0-1 on 8 H100 GPUs (Samarakoon et al. 2025 Table S4) model-execution-20261009-protocol-samarakoon2025-dv-version-h100 Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S4, row 'NA12890', column 'Parabricks DV.v4.1.0-1' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: Parabricks DeepVariant v4.1.0-1 versus v4.3.0-1 on 8 H100 GPUs (Samarakoon et al. 2025 Table S4) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	16.1 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Parabricks DV.v4.1.0-1 on 8 H100 GPUs (Samarakoon et al. 2025 Table S4) model-execution-20261009-protocol-samarakoon2025-dv-version-h100 Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S4, row 'NA12892', column 'Parabricks DV.v4.1.0-1' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	4.87 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12778', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	4.5 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12812', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	8 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12829', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	5.67 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12843', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14.7 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12877', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12878', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	15.2 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12889', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	13.8 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12890', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	13.8 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12891', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025 Table S3b.1) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	15.3 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), HaplotypeCaller or DRAGEN GSVC calling stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-hc Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.1) Variant calling via HC or DRAGEN GSVC', row 'NA12892', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	14.2 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), read mapping stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-mapping Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12778', column 'H100' (PDF page text)
Configuration: NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3) (Samarakoon et al. 2025)	Protocol: WGS germline pipeline wall-clock, read mapping stage (Samarakoon et al. 2025 Table S3a) Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage	10 runtime minute · lower Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source NVIDIA Parabricks on 8 NVIDIA H100 GPUs (GCP A3), read mapping stage (Samarakoon et al. 2025) model-execution-20261009-protocol-samarakoon2025-mapping Aggregation: Not reported Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'a) Read mapping', row 'NA12812', column 'H100' (PDF page text)

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Benchmarking accelerated next-generation sequencing analysis pipelines · Original source · Bioinformatics Advances 5(1):vbaf085, published 2025-05-15; PMC12092081 full-text XML
Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Original source · 'Publication-ready_Supplementary materials-20250404.pdf' inside vbaf085_supplementary_data.zip

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Stable ID: model-execution-20261009-config-samarakoon2025-parabricks-8xh100

areas: dna-genomes
contexts: clinical_research
method types: conventional_pipeline
foundation model eligible: false
reported name: H100
protocol: Parabricks fq2bam, ApplyBQSR, HaplotypeCaller or DeepVariant
hardware: description: 8 NVIDIA H100 (80 GB, 640 GB GPU memory in total), 1,872 GB RAM, GPFS, Google Cloud A3 VM, NVLink; host CPU per GPU type not stated
source locator: Supplementary Table S2; Methods 2.2-2.5; Table S3 column header
missing metadata: version: reason: conflicting; note: Methods 2.3 states Parabricks version 4.3.0-1; Supplementary Table S4 calls 4.1.0-1 'the version implemented in our Parabricks pipeline', and its 4.1.0-1 values equal the Table S3 b.2 H100 values.

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