rewirebio.iobenchmarks
Protocol

WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)

Wall-clock minutes for the DeepVariant calling stage on ten WGS samples, CPU-only versus Parabricks on three GPU types versus DRAGEN.

4 evaluations · 40 results

Overview

Wall-clock minutes for the DeepVariant calling stage on ten WGS samples, CPU-only versus Parabricks on three GPU types versus DRAGEN.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

4 recorded evaluations, 40 metric rows. A comparison chart has not yet been validated for these results. The table retains the individual findings and their sources.

View coverage and remaining gaps across all benchmarks

Results

Results are available, but no reviewed comparison panel is linked in this release.

All evaluations

4 evaluations · 40 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
338 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12778', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
252 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12812', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
313 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12829', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
291 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12843', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
429 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12877', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
435 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12878', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
488 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12889', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
428 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12890', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
465 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12891', column 'CPU' (PDF page text)
Configuration: CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
465 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

CPU-only best-practice pipeline on AMD EPYC 7702 (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12892', column 'CPU' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
5.98 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12778', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
4.38 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12812', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
7.5 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12829', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
5.18 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12843', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
15.3 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12877', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
16.9 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12878', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
17.6 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12889', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
13.6 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12890', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
17.4 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12891', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
17.7 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA A100 GPUs (UiO HPC), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12892', column 'A100' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
12.5 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12778', column 'L4' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
9.58 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12812', column 'L4' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
17.1 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12829', column 'L4' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
12 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12843', column 'L4' (PDF page text)
Configuration: NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2) (Samarakoon et al. 2025)Protocol: WGS germline pipeline wall-clock, DeepVariant calling stage (Samarakoon et al. 2025 Table S3b.2)
Dataset: Ten WGS samples: six Illumina Platinum pedigree high-coverage and four 1000 Genomes phase 3 low-coverage
30 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NVIDIA Parabricks on 4 NVIDIA L4 GPUs (GCP G2), DeepVariant calling stage (Samarakoon et al. 2025)

model-execution-20261009-protocol-samarakoon2025-dv

Aggregation: Not reported

Benchmarking accelerated next-generation sequencing analysis pipelines; Samarakoon et al. 2025, supplementary materials (Tables S1-S4, supplementary texts) · Supplementary Table S3 'b.2). Variant calling via DV', row 'NA12877', column 'L4' (PDF page text)

Source checking is not independent reproduction. Release 2026-10-09-8cc1db47c7f9.

Methods and evaluation design

Procedure, tasks and evaluated configurations

Recorded evaluations

Each evaluation records what was tested and under which conditions.

Baseline coverage

Reference methods help show what a model adds beyond simple controls. We track a null control and a conventional method for each protocol.

0 of 2 active baseline roles have published Rewire measurements in this release. Measurements on a selected protocol do not establish coverage of an entire suite.

No execution recipe linked to this protocol. Recipe availability does not establish a completed evaluation.

External evaluations
4

Literature evidence is not a Rewire measurement. Executed but unpublished runs and private review status are not included.

Null control

Proposed control: requires review

Select a task-valid null control after reviewing inputs and metric

Protocol-specific applicability, permitted inputs, access, split, evaluator and execution requirements need review before implementation or execution.

This is a suggested selection rule, not a validated method or a measured score.

Conventional reference

Proposed control: requires review

Select an upstream conventional reference after reviewing the full protocol

Protocol-specific applicability, permitted inputs, access, split, evaluator and execution requirements need review before implementation or execution.

This is a suggested selection rule, not a validated method or a measured score.

Protocol coverage CSV (gzip) · Model evaluation matrix (gzip) · Source table (gzip) · Release and checksums (gzip)

Coverage is derived from release 2026-10-09-8cc1db47c7f9. Source citations describe the original records; they do not validate an unreviewed baseline proposal. No results have been generated by this audit.

Run instructions

No runnable recipe has been reviewed for this protocol. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.

Strengths, limitations and unresolved questions

Evidence

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Evidence table

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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

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Claims, original sources and review scope · Release 2026-10-09-8cc1db47c7f9
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Sources and history

Release 2026-10-09-8cc1db47c7f9 · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: model-execution-20261009-protocol-samarakoon2025-dv

areas
dna-genomes
contexts
clinical_research
protocol
Variant calling with DeepVariant (CPU or Parabricks); not run on DRAGEN. Real (wall-clock) time measured per stage from FASTQ input (Methods 2.6).
version
Supplementary Table S3 sub-table 'b.2). Variant calling via DV'
unit
minute
metric
runtime
limitations
One run per sample and configuration; no repeats or variance printed.; Hardware differs between columns (CPU cluster, two GCP VMs and an HPC GPU node), so differences mix software and hardware.; CPU-only nodes were shared with other users; GCP VMs ran in a multi-tenant environment (Table S2 notes).; DRAGEN has no DeepVariant stage; its column prints NA and has no evaluation.
denominator
10
missing metadata
replicates: reason: unreported
source locator
Supplementary Table S3, sub-table 'b.2). Variant calling via DV'
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