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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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Model or configurationMetricValueDatasetEvaluation
DNABERT (3-mer)MCC70.92 unitlessGUE Core promoter detection, all (GUE split)DNABERT (3-mer) on GUE CORE-PROMOTER-DETECTION-ALL: Core promoter detection, dataset all
DNABERT (3-mer)MCC69.82 unitlessGUE Core promoter detection, notata (GUE split)DNABERT (3-mer) on GUE CORE-PROMOTER-DETECTION-NOTATA: Core promoter detection, dataset notata
DNABERT (3-mer)MCC78.15 unitlessGUE Core promoter detection, tata (GUE split)DNABERT (3-mer) on GUE CORE-PROMOTER-DETECTION-TATA: Core promoter detection, dataset tata
DNABERT (3-mer)Macro F162.23 percentGUE Covid variant classification, Covid (GUE split)DNABERT (3-mer) on GUE COVID-VARIANT-CLASSIFICATION-COVID: Covid variant classification, dataset Covid
DNABERT (3-mer)MCC74.15 unitlessGUE Epigenetic marks prediction, H3 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3: Epigenetic marks prediction, dataset H3
DNABERT (3-mer)MCC42.95 unitlessGUE Epigenetic marks prediction, H3K4me1 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K4ME1: Epigenetic marks prediction, dataset H3K4me1
DNABERT (3-mer)MCC31.34 unitlessGUE Epigenetic marks prediction, H3K4me2 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K4ME2: Epigenetic marks prediction, dataset H3K4me2
DNABERT (3-mer)MCC28.92 unitlessGUE Epigenetic marks prediction, H3K4me3 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K4ME3: Epigenetic marks prediction, dataset H3K4me3
DNABERT (3-mer)MCC50.48 unitlessGUE Epigenetic marks prediction, H3K9ac (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K9AC: Epigenetic marks prediction, dataset H3K9ac
DNABERT (3-mer)MCC42.07 unitlessGUE Epigenetic marks prediction, H3K14ac (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K14AC: Epigenetic marks prediction, dataset H3K14ac
DNABERT (3-mer)MCC48.49 unitlessGUE Epigenetic marks prediction, H3K36me3 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K36ME3: Epigenetic marks prediction, dataset H3K36me3
DNABERT (3-mer)MCC60.12 unitlessGUE Epigenetic marks prediction, H3K79me3 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K79ME3: Epigenetic marks prediction, dataset H3K79me3
DNABERT (3-mer)MCC78.27 unitlessGUE Epigenetic marks prediction, H4 (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H4: Epigenetic marks prediction, dataset H4
DNABERT (3-mer)MCC38.60 unitlessGUE Epigenetic marks prediction, H4ac (GUE split)DNABERT (3-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H4AC: Epigenetic marks prediction, dataset H4ac
DNABERT (3-mer)MCC90.44 unitlessGUE Promoter detection, all (GUE split)DNABERT (3-mer) on GUE PROMOTER-DETECTION-ALL: Promoter detection, dataset all
DNABERT (3-mer)MCC93.61 unitlessGUE Promoter detection, notata (GUE split)DNABERT (3-mer) on GUE PROMOTER-DETECTION-NOTATA: Promoter detection, dataset notata
DNABERT (3-mer)MCC69.83 unitlessGUE Promoter detection, tata (GUE split)DNABERT (3-mer) on GUE PROMOTER-DETECTION-TATA: Promoter detection, dataset tata
DNABERT (3-mer)MCC84.14 unitlessGUE Splice site prediction, Reconstruct (GUE split)DNABERT (3-mer) on GUE SPLICE-SITE-PREDICTION-RECONSTRUCT: Splice site prediction, dataset Reconstruct
DNABERT (3-mer)MCC67.95 unitlessGUE Transcription factor prediction (human), 0 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-0: Transcription factor prediction (human), dataset 0
DNABERT (3-mer)MCC70.90 unitlessGUE Transcription factor prediction (human), 1 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-1: Transcription factor prediction (human), dataset 1
DNABERT (3-mer)MCC60.51 unitlessGUE Transcription factor prediction (human), 2 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-2: Transcription factor prediction (human), dataset 2
DNABERT (3-mer)MCC53.03 unitlessGUE Transcription factor prediction (human), 3 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-3: Transcription factor prediction (human), dataset 3
DNABERT (3-mer)MCC69.76 unitlessGUE Transcription factor prediction (human), 4 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-4: Transcription factor prediction (human), dataset 4
DNABERT (3-mer)MCC42.31 unitlessGUE Transcription factor prediction (mouse), 0 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-MOUSE-0: Transcription factor prediction (mouse), dataset 0
DNABERT (3-mer)MCC79.10 unitlessGUE Transcription factor prediction (mouse), 1 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-MOUSE-1: Transcription factor prediction (mouse), dataset 1
DNABERT (3-mer)MCC69.90 unitlessGUE Transcription factor prediction (mouse), 2 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-MOUSE-2: Transcription factor prediction (mouse), dataset 2
DNABERT (3-mer)MCC55.40 unitlessGUE Transcription factor prediction (mouse), 3 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-MOUSE-3: Transcription factor prediction (mouse), dataset 3
DNABERT (3-mer)MCC41.97 unitlessGUE Transcription factor prediction (mouse), 4 (GUE split)DNABERT (3-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-MOUSE-4: Transcription factor prediction (mouse), dataset 4
DNABERT (4-mer)MCC69.00 unitlessGUE Core promoter detection, all (GUE split)DNABERT (4-mer) on GUE CORE-PROMOTER-DETECTION-ALL: Core promoter detection, dataset all
DNABERT (4-mer)MCC70.04 unitlessGUE Core promoter detection, notata (GUE split)DNABERT (4-mer) on GUE CORE-PROMOTER-DETECTION-NOTATA: Core promoter detection, dataset notata
DNABERT (4-mer)MCC74.25 unitlessGUE Core promoter detection, tata (GUE split)DNABERT (4-mer) on GUE CORE-PROMOTER-DETECTION-TATA: Core promoter detection, dataset tata
DNABERT (4-mer)Macro F159.87 percentGUE Covid variant classification, Covid (GUE split)DNABERT (4-mer) on GUE COVID-VARIANT-CLASSIFICATION-COVID: Covid variant classification, dataset Covid
DNABERT (4-mer)MCC73.03 unitlessGUE Epigenetic marks prediction, H3 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3: Epigenetic marks prediction, dataset H3
DNABERT (4-mer)MCC41.06 unitlessGUE Epigenetic marks prediction, H3K4me1 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K4ME1: Epigenetic marks prediction, dataset H3K4me1
DNABERT (4-mer)MCC30.66 unitlessGUE Epigenetic marks prediction, H3K4me2 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K4ME2: Epigenetic marks prediction, dataset H3K4me2
DNABERT (4-mer)MCC25.31 unitlessGUE Epigenetic marks prediction, H3K4me3 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K4ME3: Epigenetic marks prediction, dataset H3K4me3
DNABERT (4-mer)MCC51.44 unitlessGUE Epigenetic marks prediction, H3K9ac (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K9AC: Epigenetic marks prediction, dataset H3K9ac
DNABERT (4-mer)MCC41.88 unitlessGUE Epigenetic marks prediction, H3K14ac (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K14AC: Epigenetic marks prediction, dataset H3K14ac
DNABERT (4-mer)MCC48.03 unitlessGUE Epigenetic marks prediction, H3K36me3 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K36ME3: Epigenetic marks prediction, dataset H3K36me3
DNABERT (4-mer)MCC59.77 unitlessGUE Epigenetic marks prediction, H3K79me3 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H3K79ME3: Epigenetic marks prediction, dataset H3K79me3
DNABERT (4-mer)MCC78.28 unitlessGUE Epigenetic marks prediction, H4 (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H4: Epigenetic marks prediction, dataset H4
DNABERT (4-mer)MCC36.40 unitlessGUE Epigenetic marks prediction, H4ac (GUE split)DNABERT (4-mer) on GUE EPIGENETIC-MARKS-PREDICTION-H4AC: Epigenetic marks prediction, dataset H4ac
DNABERT (4-mer)MCC89.54 unitlessGUE Promoter detection, all (GUE split)DNABERT (4-mer) on GUE PROMOTER-DETECTION-ALL: Promoter detection, dataset all
DNABERT (4-mer)MCC92.65 unitlessGUE Promoter detection, notata (GUE split)DNABERT (4-mer) on GUE PROMOTER-DETECTION-NOTATA: Promoter detection, dataset notata
DNABERT (4-mer)MCC66.78 unitlessGUE Promoter detection, tata (GUE split)DNABERT (4-mer) on GUE PROMOTER-DETECTION-TATA: Promoter detection, dataset tata
DNABERT (4-mer)MCC84.05 unitlessGUE Splice site prediction, Reconstruct (GUE split)DNABERT (4-mer) on GUE SPLICE-SITE-PREDICTION-RECONSTRUCT: Splice site prediction, dataset Reconstruct
DNABERT (4-mer)MCC67.90 unitlessGUE Transcription factor prediction (human), 0 (GUE split)DNABERT (4-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-0: Transcription factor prediction (human), dataset 0
DNABERT (4-mer)MCC73.05 unitlessGUE Transcription factor prediction (human), 1 (GUE split)DNABERT (4-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-1: Transcription factor prediction (human), dataset 1
DNABERT (4-mer)MCC59.52 unitlessGUE Transcription factor prediction (human), 2 (GUE split)DNABERT (4-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-2: Transcription factor prediction (human), dataset 2
DNABERT (4-mer)MCC50.37 unitlessGUE Transcription factor prediction (human), 3 (GUE split)DNABERT (4-mer) on GUE TRANSCRIPTION-FACTOR-PREDICTION-HUMAN-3: Transcription factor prediction (human), dataset 3

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Models, benchmarks and other records

Configurations (10)

Benchmarks (1)

Tasks (29)

Dataset subsets (28)

Evaluations (280)

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Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
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49300acee3e4afd44bebc3de9893c3bc310d331bd4805374e0952fdfbf366f06
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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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Url
https://arxiv.org/pdf/2306.15006
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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genomes

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url
https://arxiv.org/pdf/2306.15006
version
Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
retrieved at
2026-09-17T08:06:28.183387+00:00
artifact sha256
49300acee3e4afd44bebc3de9893c3bc310d331bd4805374e0952fdfbf366f06
artifact url
https://arxiv.org/pdf/2306.15006
hash scope
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review
scope: Source identification and table transcription; no independent experimental reproduction.; method: automated-source-review
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