rewirebio.iobenchmarks
Source

scFoundation primary supplement, Table4

Nature Methods · 10.1038/s41592-024-02305-7 publisher supplement

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Model or configurationMetricValueDatasetEvaluation
ACTINNMacro F10.722 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)ACTINN on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
ACTINNMacro F10.649 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)ACTINN on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation
CellTypistMacro F10.812 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)CellTypist on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
CellTypistMacro F10.725 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)CellTypist on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation
ScanpyMacro F10.540 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)Scanpy on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
ScanpyMacro F10.547 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)Scanpy on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation
scANVIMacro F10.521 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)scANVI on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
scANVIMacro F10.395 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)scANVI on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation
scBERTMacro F10.670 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)scBERT on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
scBERTMacro F10.670 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)scBERT on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation
scFoundationMacro F10.914 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)scFoundation on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
scFoundationMacro F10.736 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)scFoundation on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation
SingleCellNetMacro F10.806 fractionSegerstolpe subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)SingleCellNet on scFoundation cell-type annotation comparison Segerstolpe: Segerstolpe cell-type annotation
SingleCellNetMacro F10.598 fractionZheng68K subset used in scFoundation Supplementary Table4 (scFoundation cell-type annotation comparison split)SingleCellNet on scFoundation cell-type annotation comparison Zheng68K: Zheng68K cell-type annotation

Claims

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  • ACTINN: description: Description Cell-type classifier for single-cell RNA-seq that trains a neural network with three hidden layers on datasets with predefined cell types and predicts cell types in other datasets. (qa-descriptions-20261011-b-source-actinn: abstractText; coverage-source-scfoundation-supp: Supplementary Table 4 (cell type annotation on Zheng68K and Segerstolpe))
  • CellTypist: description: Description Machine-learning tool for rapid cell-type annotation of single-cell RNA-seq data. (qa-descriptions-20261011-b-source-celltypist: abstractText ('CellTypist, a machine learning tool for rapid and precise cell type annotation'); coverage-source-scfoundation-supp: Supplementary Table 4)
  • Scanpy: description: Description Python toolkit for single-cell gene expression analysis, with methods for preprocessing, visualisation, clustering, trajectory inference and differential expression testing. (qa-descriptions-20261011-b-source-scanpy: abstractText; coverage-source-scfoundation-supp: Supplementary Table 4)
  • scANVI: description: Description Semi-supervised variant of scVI, a deep generative model of single-cell transcriptomics, that uses existing cell-state annotations to label cells in new datasets. (qa-descriptions-20261011-b-source-scanvi: abstractText ('scANVI, a semi-supervised variant of scVI designed to leverage existing cell state annotations'); coverage-source-scfoundation-supp: Supplementary Table 4)
  • scBERT: description: Description Transformer model, pretrained on unlabelled single-cell RNA-seq data in the manner of BERT, that is fine-tuned to annotate cell types. (qa-descriptions-20261011-b-source-scbert: abstractText; coverage-source-scfoundation-supp: Supplementary Table 4)
  • scFoundation cell-type annotation comparison Segerstolpe: part of model-coverage-scfoundation-cell-annotation: Part of scFoundation cell-type annotation comparison (Supplementary Table4, PDF p16; Supplementary Note3, Macro F1 score.)
  • scFoundation cell-type annotation comparison Zheng68K: part of model-coverage-scfoundation-cell-annotation: Part of scFoundation cell-type annotation comparison (Supplementary Table4, PDF p16; Supplementary Note3, Macro F1 score.)
  • scFoundation: description: Description Cell-type annotation with scFoundation, a model that produces contextual cell and gene representations from gene-expression measurements. (catalog-model-scfoundation profile summary (evidence-official-9863509ad10b824dc96b: Results pre-training framework; Methods Embedding, Encoder, Decoder); coverage-source-scfoundation-supp: Supplementary Table 4)
  • scFoundation: uses model catalog-model-scfoundation: Uses model scFoundation (Supplementary Table4, PDF p16, row scFoundation)
  • SingleCellNet: description: Description Tool that classifies query single-cell RNA-seq data by comparison with reference single-cell RNA-seq data, across platforms and species. (qa-descriptions-20261011-b-source-singlecellnet: title and abstractText; coverage-source-scfoundation-supp: Supplementary Table 4)

Models, benchmarks and other records

Pipelines (7)

Benchmarks (1)

Protocols (2)

Dataset subsets (2)

Evaluations (14)

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Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Artifact SHA-256
9ef9ed1b87014fb72b22cfc99a5382b01e6a6395a0c5de36921d155848162ae1
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scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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https://static-content.springer.com/esm/art%3A10.1038%2Fs41592-024-02305-7/MediaObjects/41592_2024_2305_MOESM1_ESM.pdf
Source metadata
scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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2026-09-23T11:36:02.116209+00:00
Source metadata
scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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Url
https://doi.org/10.1038/s41592-024-02305-7
Source metadata
scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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Venue
Nature Methods
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scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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10.1038/s41592-024-02305-7 publisher supplement
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scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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Description
Pinned primary artifact. Review is limited to the cited rows.
Source metadata
scFoundation primary supplement, Table4

Original source ↗

No field-specific location recorded

Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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Facets: areas
1 values
  • single-cell
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scFoundation primary supplement, Table4

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coverage-source-scfoundation-supp
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scFoundation primary supplement, Table4

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scFoundation primary supplement, Table4

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Version: 10.1038/s41592-024-02305-7 publisher supplement
Retrieved: 2026-09-23T11:36:02.116209+00:00

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areas
single-cell
url
https://doi.org/10.1038/s41592-024-02305-7
artifact url
https://static-content.springer.com/esm/art%3A10.1038%2Fs41592-024-02305-7/MediaObjects/41592_2024_2305_MOESM1_ESM.pdf
artifact sha256
9ef9ed1b87014fb72b22cfc99a5382b01e6a6395a0c5de36921d155848162ae1
retrieved at
2026-09-23T11:36:02.116209+00:00
venue
Nature Methods
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10.1038/s41592-024-02305-7 publisher supplement
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