rewirebio.iobenchmarks
Result

Recall (episode-level predictive sensitivity; bacterial bloodstream infections; raw data; reference: organisms identified by blood culture) of Karius mcfDNA-Seq, all positive tests (Wolf et al. 2026) on Bloodstream infection episodes in children and young people with high-risk leukaemia (Wolf et al. 2026)

53·8% Recall (episode-level predictive sensitivity; bacterial bloodstream infections; raw data; reference: organisms identified by blood culture)

Methods

Tested configuration
Karius mcfDNA-Seq, all positive tests (Wolf et al. 2026)
Protocol
Predictive sensitivity, day -3 to -1 (Wolf et al. 2026 Table 2)
Dataset
Bloodstream infection episodes in children and young people with high-risk leukaemia (Wolf et al. 2026)
Procedure
Predictive sensitivity, day -3 to -1 (Wolf et al. 2026 Table 2)
Evaluation
Karius mcfDNA-Seq (all positive tests) on Predictive sensitivity, day -3 to -1 (Wolf et al. 2026 Table 2)
Coverage
Not reported scored / Not reported eligible
Uncertainty
95% CI 42.2 to 65.2
Evidence
Author-reported evaluation · source checkedPredicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study · Table 2, group 'Bacterial bloodstream infections (n=91)', row 'Prediction (day −3 to −1)', block 'Raw data', column 'Sensitivity'

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split
Single cohort
Adaptation
Any organism reported by the laboratory counts as positive.
Scoring implementation
Proportion of evaluable bloodstream infection episodes in which all organisms identified by blood culture were detected by mcfDNA-Seq in at least one sample from the 3 days before onset.

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Reported result
53·8%
Individual claims
Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study

Original source ↗

Table 2, group 'Bacterial bloodstream infections (n=91)', row 'Prediction (day −3 to −1)', block 'Raw data', column 'Sensitivity'

Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript)
Retrieved: 2026-10-11T22:07:34Z

source checked

["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-11

author reported

Audit details

Re-downloaded the pinned artifact and matched its SHA-256; compared every value with a separate stdlib parser written for this review (the extractor's script was not run) and checked a stratified sample by hand against the rendered table.

Field: attributes.printed_value

Source artifact SHA-256: 0f6905d0a0c9ace686bcc61970c711558ccf530b5c31f882607a305f8b5ca689

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Extraction artifact SHA-256: 0f6905d0a0c9ace686bcc61970c711558ccf530b5c31f882607a305f8b5ca689

Extraction artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: dna-pathogen-20261011-wolf2026-result-prediction-bacterial-raw-sensitivity

metric
recall
metric direction
higher
unit
percent
printed value
53·8%
numeric value
53.8
metric qualifier
episode-level predictive sensitivity; bacterial bloodstream infections; raw data; reference: organisms identified by blood culture
source locator
Table 2, group 'Bacterial bloodstream infections (n=91)', row 'Prediction (day −3 to −1)', block 'Raw data', column 'Sensitivity'
numerator
42
denominator
78
uncertainty
type: confidence_interval; lower: 42.2; upper: 65.2; level: 0.95; printed: (42·2–65·2)
review
method: source-hash-verification; deterministic-table-parse; independent-cell-check; reviewer: claude; reviewer note: Separate Claude review agent (reviewer-path), independent of the extractor; no human review claimed; date: 2026-10-11; artifact sha256: 0f6905d0a0c9ace686bcc61970c711558ccf530b5c31f882607a305f8b5ca689; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC13154368/fullTextXML; method note: Extracted by deterministic parse of the pinned Europe PMC full-text XML (extract/extract_wolf2026.py), with row and column labels asserted. printed_value is the cell text exactly.; note: Re-downloaded the pinned artifact and matched its SHA-256; compared every value with a separate stdlib parser written for this review (the extractor's script was not run) and checked a stratified sample by hand against the rendered table.
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