Protocol

CPPC original Challenge 1 final four-knockout prediction score

Mean over four held-out knockouts of SUM of five absolute state-proportion errors. Three other held-out genes provide validation feedback. Original submitted methods, not post-hoc reimplementations.

20 evaluations · 20 results

Overview

Mean over four held-out knockouts of SUM of five absolute state-proportion errors. Three other held-out genes provide validation feedback. Original submitted methods, not post-hoc reimplementations.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

20 recorded evaluations, 20 metric rows. A comparison chart has not yet been validated for these results. The table retains the individual findings and their sources.

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Results

Results are available, but no reviewed comparison panel is linked in this release.

All evaluations

20 evaluations · 20 results. Different protocols are not a single leaderboard.

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Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: CPPC original submission row 10 (unnamed method)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.799 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 10 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C10; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 11 (unnamed method)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.799 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 11 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C11; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 12 (5Features)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.813 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 12 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C12; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 13 (unnamed method)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.815 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 13 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C13; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 14 (unnamed method)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.82 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 14 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C14; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 15 (unnamed method)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.829 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 15 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C15; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 16 (scETM)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.849 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 16 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C16; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 17 (scTenifoldNet)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.859 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 17 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C17; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 18 (GO_knn)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.901 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 18 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C18; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 19 (LowExp)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.913 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 19 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C19; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 2 (PPI_Weighted)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.714 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 2 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C2; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 20 (unnamed method)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.92 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 20 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C20; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 21 (interv)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	1.27 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 21 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C21; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 3 (GWPS_K562 (H2M))	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.75 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 3 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C3; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 4 (14Features)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.764 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 4 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C4; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 5 (scBERT)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.767 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 5 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C5; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 6 (scVI)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.779 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 6 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C6; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 7 (Expression_Conditioned)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.788 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 7 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C7; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 8 (Exon)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.789 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 8 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C8; raw XLSX numeric value (not rounded display)
Configuration: CPPC original submission row 9 (Gene2Vec)	Protocol: CPPC original Challenge 1 final four-knockout prediction score Dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens	0.79 mean-summed-cell-state-l1 summed absolute proportion error · lower Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source cppc table s2 c row 9 Not reported Aggregation: Not reported CPPC Table S2 original and reimplemented submission comparisons · Supplementary Table S2; media-3.xlsx sheet 'Challenge 1 & 2'; cell C9; raw XLSX numeric value (not rounded display)

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Author-reported evaluations: 20

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3 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-30-e37e3ab1284d
Property and statement	Original source and location	Review and provenance
Relationship: part of ucc-research-benchmark-cppc Individual claims	Cancer Immunotherapy Data Science Challenge official code Original source ↗ Challenge setup and results; Supplementary Table S2 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 283328a9b8afc6e882eeb503ac4710bbe9f37371 Retrieved: 2026-09-30T21:26:16Z	source checked automated source review · 2026-09-30T21:43:56Z Audit details Primary-source table transcription and scope review; no independent reproduction or human scientific review. Field: `links:part_of:ucc-research-benchmark-cppc` Claim: ucc-research-membership-cppc-challenge1-original Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Relationship: part of ucc-research-benchmark-cppc Individual claims	Cancer Immunotherapy Data Science Challenge Original source ↗ Challenge setup and results; Supplementary Table S2 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 10.64898/2026.05.21.726863v1; 2026 preprint Retrieved: 2026-09-30T21:23:33Z	source checked automated source review · 2026-09-30T21:43:56Z Audit details Primary-source table transcription and scope review; no independent reproduction or human scientific review. Field: `links:part_of:ucc-research-benchmark-cppc` Claim: ucc-research-membership-cppc-challenge1-original Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Relationship: part of ucc-research-benchmark-cppc Individual claims	CPPC Table S2 original and reimplemented submission comparisons Original source ↗ Challenge setup and results; Supplementary Table S2 Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Table S2 media-3.xlsx, 10.64898/2026.05.21.726863v1 Retrieved: 2026-09-30T21:40:24Z	source checked automated source review · 2026-09-30T21:43:56Z Audit details Primary-source table transcription and scope review; no independent reproduction or human scientific review. Field: `links:part_of:ucc-research-benchmark-cppc` Claim: ucc-research-membership-cppc-challenge1-original Source artifact SHA-256: `ed480039c8008fdfcedaa50a8248d32df6068a9230a18ab6953ada5535865105` Hash scope: Hash scope not separately documented; inspect source record Archive member: media-3.xlsx Inspected artifact

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Release 2026-09-30-e37e3ab1284d · Record review: source checked

2 source records and release history

Cancer Immunotherapy Data Science Challenge · Original source · 10.64898/2026.05.21.726863v1; 2026 preprint
CPPC Table S2 original and reimplemented submission comparisons · Original source · Table S2 media-3.xlsx, 10.64898/2026.05.21.726863v1

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Technical metadata and extraction receipts

Stable ID: ucc-research-protocol-cppc-challenge1-original

review: method: automated_source_review; actor: Codex research coverage worker; reviewed at: 2026-09-30T21:43:56Z; note: Primary-source table transcription and scope review; no independent reproduction or human scientific review.
heldout validation: Aqr; Bach2; Bhlhe40
heldout test: Ets1; Fosb; Mafk; Stat3
metric definition: L1 summed over five cell states, averaged over four final held-out knockouts; range 0–2

Related records

dataset: CPPC B16-OVA mouse melanoma T-cell perturbation screens
part of: Cancer Immunotherapy Data Science Challenge
protocol: cppc table s2 c row 10
protocol: cppc table s2 c row 11
protocol: cppc table s2 c row 12
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protocol: cppc table s2 c row 8
protocol: cppc table s2 c row 9
subject: Source membership: ucc-research-protocol-cppc-challenge1-original

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