Model type
Generative single-cell transformer
scGPT learns representations of single-cell molecular measurements and supports task-specific adaptation.
3 evaluations · 3 results · 3 evaluated configurations using this model
Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation.
Generative single-cell transformer
Gene-expression measurements with the checkpoint-matched gene vocabulary.
Cell/gene representations and task-specific predictions after the relevant workflow.
Official project documentation and implementation: https://github.com/bowang-lab/scGPT
limited source coverage · Automated source review, 2026-09-23. All specifications and missing details
3 evaluations · 3 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: scGPT | Task: Cell-type identification Dataset: M.S. single-cell dataset | 0.734 F1-Score unitless · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcescGPT: Cell-type identification Native scLLM cell-type identification as reported in Table 2. Aggregation: Not reported Parameter-Efficient Fine-Tuning Enhances Adaptation of Single Cell Large Language Model for Cell Type Identification · Table 2, M.S. / scGPT row, F1-Score column |
| Configuration: scGPT | Task: Cell-type annotation Dataset: hPancreas | 0.55 F1 unitless · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Result quoted from another source · Source checkedMethods, coverage and sourceZero-shot setting; source caption says some comparator rows come from GenePT. Aggregation: Not reported scELMo: Embeddings from Language Models are Good Learners for Single-cell Data Analysis · Table 1, hPancreas zero-shot / scGPT (z) row, F1 column |
| Configuration: scGPT | Task: Cell-type structure in frozen embeddings Dataset: Aorta single-cell dataset | 0.47 Adjusted Rand Index unitless · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourcescGPT: Cell-type structure in frozen embeddings k-means on pretrained cell embeddings; agreement with original cell-type labels. Aggregation: Not reported GenePT: A Simple But Effective Foundation Model for Genes and Cells Built From ChatGPT · Table 2, Aorta / Cell type row, scGPT ARI column |
Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.
These configurations, services and pipelines use this model within their own configurations. Their results, where available, are not assigned to the underlying model.
Related profile: scGPT. This page retains the exact record and its evaluation context.
scGPT combines each gene identity with its expression-value encoding before transformer attention. The implementation supports several expression encoders and cell-pooling choices. Task heads then predict expression or cell labels; optional masking and batch objectives depend on the training configuration.
The May 2023 preprint reports an early 10M-cell model. The current whole-human checkpoint table reports 33M normal human cells; these sources describe different releases. The applicable input limits require configuration-specific checking.
Follow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied.
Stable record: catalog-model-scgptExplanatory profile: limited source coverage · Automated source review, 2026-09-23. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
| Property | Description and evidence |
|---|---|
| Model type | Generative single-cell transformerSources (3)bowang-lab/scGPT: README.md; bowang-lab/scGPT: scgpt/model/model.py; scgpt-may2023: Primary paper PDF · May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row |
| Architecture | Transformer backbone combining learned gene-token embeddings with expression-value encodings and optional batch encodings. Separate expression, cell-classification and optional masked-value or batch-discriminator heads support configured tasks.Sources (3)bowang-lab/scGPT: README.md; bowang-lab/scGPT: scgpt/model/model.py; scgpt-may2023: Primary paper PDF · May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row |
| Inputs | Gene-expression measurements with the checkpoint-matched gene vocabulary.Sources (3)bowang-lab/scGPT: README.md; bowang-lab/scGPT: scgpt/model/model.py; scgpt-may2023: Primary paper PDF · May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row |
| Outputs | Cell/gene representations and task-specific predictions after the relevant workflow.Sources (3)bowang-lab/scGPT: README.md; bowang-lab/scGPT: scgpt/model/model.py; scgpt-may2023: Primary paper PDF · May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row |
| Parameters | No exact whole-human checkpoint parameter total is stated in the inspected official README, embedding loader or journal supplement. The loader reads architecture settings from the selected checkpoint’s args.json; a family label alone does not identify its weights or task heads. · Not reported in inspected sourcesSources (3)bowang-lab/scGPT: README.md; scGPT official embedding workflow implementation; scGPT Nature Methods original supplementary information · README Pretrained scGPT Model Zoo; cell_emb.py lines202-247 args.json loading and TransformerModel construction; complete original supplementary PDF inspected for parameter totals. |
| Known versions | Whole-human, blood, brain, heart, kidney, lung, pan-cancer and additional organ-specific checkpoint folders are listed separately. An evaluation needs its downloaded weights, args.json and vocabulary; current documentation is not an evaluated checkpoint hash.Sources (2)bowang-lab/scGPT: README.md; scGPT official embedding workflow implementation · README Pretrained scGPT Model Zoo; cell_emb.py lines202-247 model configuration, vocabulary and checkpoint loading. |
| Training data | The official whole-human release is described as pretrained on 33 million normal human cells. The corpus-construction documentation names CELLxGENE Census 2023-05-08 and filters disease=normal. The author later clarified that 2023-05-15 was assumed to be a similar replacement after the earlier snapshot disappeared; exact equality was not established.Sources (4)bowang-lab/scGPT: README.md; scGPT official training corpus construction documentation; scGPT official CELLxGENE query configuration; scGPT author clarification of CELLxGENE corpus version · README.md lines58-62, whole-human row; data/cellxgene/README.md Configure Query List, VERSION bullet; data_config.py VERSION and VALUE_FILTER; issue233 comment2261459134 by repository MEMBER subercui, 2024-07-31. |
| Training cutoff | The historical corpus date is documented as CELLxGENE 2023-05-08, with a later 2023-05-15 replacement ambiguity. Neither is a verified latest-study date for every trained cell. The archived corpus and evaluated checkpoint must be identified separately. · Not reported in inspected sourcesSources (2)scGPT official training corpus construction documentation; scGPT author clarification of CELLxGENE corpus version · data/cellxgene/README.md VERSION bullet; issue233 comment2261459134 (author distinguishes historical snapshot from presumed replacement). |
| Context limits | The official embed_data workflow defaults to max_length=1200 input tokens and allows the caller to change it. This is an embedding-workflow setting, not a validated universal context ceiling or proof of the setting used in a published evaluation.SourcesscGPT official embedding workflow implementation · scgpt/tasks/cell_emb.py embed_data signature lines148-167; get_batch_cell_embeddings max_length handling and DataCollator. |
| Weights licence | The inspected official model-zoo download table does not state a separate licence grant for the downloaded whole-human checkpoint. The repository MIT code licence is recorded separately; it is not treated as proof of explicit checkpoint-distribution terms. · Not reported in inspected sourcesSources (2)bowang-lab/scGPT: README.md; bowang-lab/scGPT: LICENSE · README Pretrained scGPT Model Zoo checkpoint-folder links; LICENSE software grant. |
| Access | Official project documentation and implementation: https://github.com/bowang-lab/scGPTSources (3)bowang-lab/scGPT: README.md; bowang-lab/scGPT: scgpt/model/model.py; scgpt-may2023: Primary paper PDF · May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row |
| Code licence | MIT for the repository code at commit cebd6fae655b9c585a4807daa3ac31bb764f06b4.Sourcesbowang-lab/scGPT: LICENSE · LICENSE, MIT grant and copyright notice. |
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
55 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims | bowang-lab/scGPT: README.md May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims | bowang-lab/scGPT: scgpt/model/model.py May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims | scgpt-may2023: Primary paper PDF May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv version posted 1 May 2023; re-inspected existing local research artifact | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
Diagram steps
| bowang-lab/scGPT: README.md May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
Diagram steps
| bowang-lab/scGPT: scgpt/model/model.py May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
Diagram steps
| scgpt-may2023: Primary paper PDF May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv version posted 1 May 2023; re-inspected existing local research artifact | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Diagram title scGPT workflow Individual claims | bowang-lab/scGPT: README.md May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Diagram title scGPT workflow Individual claims | bowang-lab/scGPT: scgpt/model/model.py May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Diagram title scGPT workflow Individual claims | scgpt-may2023: Primary paper PDF May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv version posted 1 May 2023; re-inspected existing local research artifact | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Model type Generative single-cell transformer Individual claims | bowang-lab/scGPT: README.md May 2023 scGPT preprint Sections 4.1–4.3 and 4.8; current scgpt/model/model.py and README pretrained model table; README.md: Pretrained scGPT Model Zoo, whole-human row Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: cebd6fae655b9c585a4807daa3ac31bb764f06b4 | source checked automated source review · 2026-09-23 Audit detailsFollow-up review of Training data, Training cutoff, Context limits, Parameters, Code licence, Weights licence, Known versions. Source locations and before/after decisions are recorded in the 23 September profile-evidence audit. Other explanatory content retains its earlier source scope. No human scientific review or independent reproduction is implied. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
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Release 2026-09-29-06401fd5b220 · Record review: discovered
Stable ID: catalog-model-scgpt