rewire.itbenchmarks
Evaluation

ESM2 8M: Held-out human-versus-virus protein classification

Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.

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Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

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Verified: Not verified

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Investigate discrepancies

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Verified: Not verified

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Evaluation results

1 evaluation · 4 results. Different protocols are not a single leaderboard.

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Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: ESM2 8MProtocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification)
Dataset: human and viral proteins
92.2% Prec.
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2 8M: Held-out human-versus-virus protein classification

Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.

Aggregation: Not reported

Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column Prec.; XML row4 column4
Configuration: ESM2 8MProtocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification)
Dataset: human and viral proteins
92.3% Recall
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2 8M: Held-out human-versus-virus protein classification

Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.

Aggregation: Not reported

Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column Recall; XML row4 column5
Configuration: ESM2 8MProtocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification)
Dataset: human and viral proteins
98.1% AUROC
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2 8M: Held-out human-versus-virus protein classification

Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.

Aggregation: Not reported

Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column AUC (%); XML row4 column2
Configuration: ESM2 8MProtocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification)
Dataset: human and viral proteins
94.7% Accur.
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

ESM2 8M: Held-out human-versus-virus protein classification

Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.

Aggregation: Not reported

Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column Accur.; XML row4 column3

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Evaluation procedure

Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.

Configuration
ESM2 8M
Protocol
Held-out human-versus-virus protein classification (human-versus-viral protein classification)
Dataset
human and viral proteins
origin
Author-reported evaluation
configuration
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
protocol id
paper-protocol-1352834b9391c1dacb
dataset version
Not reported
split
UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.
subset
Held-out human-versus-virus protein classification
population
Not reported
aggregation
Precision and recall macro-averaged over classes; AUROC and log-loss computed with scikit-learn.
inputs
Not reported
adaptation
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
budget
Not reported
metric implementation
Not reported

Metadata review: needs review. Unreported conditions prevent automatic comparisons.

Reproduction

Split
UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.
Adaptation
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
Scoring implementation
Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

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Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

19 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.aggregation
Precision and recall macro-averaged over classes; AUROC and log-loss computed with scikit-learn.
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.inputs
Not reported
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.metric_implementation
Not reported
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.population
Not reported
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.protocol_id
paper-protocol-1352834b9391c1dacb
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.split
UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.subset
Held-out human-versus-virus protein classification
Context-only references
Protein Language Models Expose Viral Immune Mimicry

Original source ↗

Table 1: AUC (%), Held-out human-versus-virus protein classification

Version: version of record
Retrieved: 2026-09-17T07:56:17.192528+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.subset

Source artifact SHA-256: 15250af2f75f70e2b6a3725d00bc7e276ed9d2d4a54f0ae9d6eaabf6be13e4a1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-29-06401fd5b220 · Record review: needs review

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: paper-evaluation-8a89666251b30349ea

areas
proteins-complexes
tasks
human-versus-viral protein classification
origin
author_reported
protocol
Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.
version
Paper-specific evaluated pipeline; exact checkpoint not inferred from label
comparison
protocol id: paper-protocol-1352834b9391c1dacb; dataset version: Not reported; split: UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1.; subset: Held-out human-versus-virus protein classification; population: Not reported; aggregation: Precision and recall macro-averaged over classes; AUROC and log-loss computed with scikit-learn.; inputs: Not reported; adaptation: Paper-specific evaluated pipeline; exact checkpoint not inferred from label; budget: Not reported; metric implementation: Not reported
source locator
Table 1: AUC (%), Held-out human-versus-virus protein classification
missing metadata
checkpoint revision: unextracted; budget: unreported; split manifest: unextracted
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