| Configuration: ESM2 650M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 99.7% AUROC percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 650M: human-versus-viral protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry; Protein Language Models Expose Viral Immune Mimicry · Table 1, ESM2 650M row, AUC (%) column |
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| Configuration: ESM2 8M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 92.2% Prec. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 8M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column Prec.; XML row4 column4 |
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| Configuration: AA n-grams | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 91.5% AUROC percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceAA n-grams: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row AA n-grams, column AUC (%); XML row3 column2 |
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| Configuration: AA n-grams | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 88.5% Prec. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceAA n-grams: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row AA n-grams, column Prec.; XML row3 column4 |
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| Configuration: ESM2 650M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 96.8% Prec. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 650M: human-versus-viral protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 650M, column Prec.; XML row7 column4 |
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| Configuration: ESM2 35M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 98.7% AUROC percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 35M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 35M, column AUC (%); XML row5 column2 |
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| Configuration: ESM2 35M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 93.8% Prec. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 35M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 35M, column Prec.; XML row5 column4 |
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| Configuration: ESM2 150M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 95.5% Prec. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 150M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 150M, column Prec.; XML row6 column4 |
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| Configuration: Tree-T5 | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 97.7% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTree-T5: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row Tree-T5, column Recall; XML row9 column5 |
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| Configuration: ESM2 150M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 97% Accur. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 150M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 150M, column Accur.; XML row6 column3 |
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| Configuration: ESM2 35M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 93.9% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 35M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 35M, column Recall; XML row5 column5 |
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| Configuration: Tree-T5 | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 97.7% Accur. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTree-T5: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row Tree-T5, column Accur.; XML row9 column3 |
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| Configuration: ESM2 8M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 92.3% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 8M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column Recall; XML row4 column5 |
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| Configuration: ESM2 35M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 95.8% Accur. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 35M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 35M, column Accur.; XML row5 column3 |
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| Configuration: Tree-T5 | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 99.7% AUROC percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceTree-T5: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row Tree-T5, column AUC (%); XML row9 column2 |
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| Configuration: Linear-T5 | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 97.6% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceLinear-T5: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row Linear-T5, column Recall; XML row8 column5 |
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| Configuration: ESM2 650M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 97.9% Accur. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 650M: human-versus-viral protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 650M, column Accur.; XML row7 column3 |
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| Configuration: Linear-T5 | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 97.6% Accur. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceLinear-T5: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row Linear-T5, column Accur.; XML row8 column3 |
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| Configuration: BL Length | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 78.5% Accur. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceBL Length: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row BL Length, column Accur.; XML row2 column3 |
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| Configuration: ESM2 150M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 95.5% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 150M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 150M, column Recall; XML row6 column5 |
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| Configuration: ESM2 8M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 98.1% AUROC percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 8M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 8M, column AUC (%); XML row4 column2 |
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| Configuration: ESM2 650M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 96.7% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 650M: human-versus-viral protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 650M, column Recall; XML row7 column5 |
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| Configuration: ESM2 150M | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 99.3% AUROC percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM2 150M: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row ESM2 150M, column AUC (%); XML row6 column2 |
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| Configuration: BL Length | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 78.5% Prec. percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceBL Length: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row BL Length, column Prec.; XML row2 column4 |
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| Configuration: BL Length | Protocol: Held-out human-versus-virus protein classification (human-versus-viral protein classification) Dataset: human and viral proteins | 78.5% Recall percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceBL Length: Held-out human-versus-virus protein classification Compare protein origin classifiers; T 5 embeddings plus linear/tree models vs ESM 2 fine-tuning and simple controls. UniRef90 deduplication; proteins longer than1,600 residues excluded; UniRef50 clusters assigned80% training and20% test with no cluster shared. Separate four-fold error-analysis experiment not assigned toTable1. Aggregation: Not reported Protein Language Models Expose Viral Immune Mimicry · Table 1, row BL Length, column Recall; XML row2 column5 |
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