Published comparison transcribed from the pinned source; not reproduced.
1 evaluation · 1 result. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: ESM-2 650M, the CLS token embedding, not fine-tuned (PRIME) | Protocol: PRIME ACE2 binding regression, Random split over RBD mutants, R² Dataset: SARS-CoV-2 RBD mutant binding and expression measurements | 0.7694 ± 0.13 R² (ACE2 binding; Random split over RBD mutants; the CLS token embedding, frozen) unitless · higher Uncertainty: SD 0.13 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceESM-2 650M CLS frozen: ACE2 binding R², Random split over RBD mutants lit-protein-20261011-prime-protocol-random-binding-r2 Aggregation: Not reported PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' |
Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified
Exact outcomes, predictions, identifiers and evaluator are connected.
Missing or unresolved evidence
Verified: Not verified
Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.
Missing or unresolved evidence
Verified: Not verified
A pinned recipe describes the inputs, environment and resource requirements.
Missing or unresolved evidence
Verified: Not verified
Separate data and exposure records support an independent test.
Missing or unresolved evidence
Verified: Not verified
Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.
No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.
PRIME ACE2 binding regression, Random split over RBD mutants, R²
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
18 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation Supervised regression head on the representations Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Mean with standard deviation across random seeds, over five cross-validation folds (Table 1 footnote; Fig. 1C) Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version Not reported Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: inputs RBD mutant sequence; the CLS token embedding, frozen Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: metric implementation R² Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: population RBD mutants with measured binding and expression Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: protocol id lit-protein-20261011-prime-protocol-random-binding-r2 Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: split Random split over RBD mutants Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Origin author_reported Context-only references | PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space Table 1, row 'ESM-2 650M' / 'CLS' / '×', columns 'Random Split' / 'Binding' / 'R²' Version: Version of record, BMC Genomics 2026 (PMC13425921 JATS full text) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: lit-protein-20261011-prime-eval-random-binding-r2-esm-2-650m-cls-frozen