Published prospective cohort result; transcribed, not reproduced.
1 evaluation · 4 results. Different protocols are not a single leaderboard.
Protocol: Predictive specificity in control samples (Wolf et al. 2026 Table 3) · Dataset: Control plasma samples without fever or infection (Wolf et al. 2026)
Sorted by Specificity (predictive specificity; any bacterium or yeast (Burkholderia, moulds, viruses and parasites excluded); control samples without fever or infection within 7 days) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Specificity (predictive specificity; any bacterium or yeast (Burkholderia, moulds, viruses and parasites excluded); control samples without fever or infection within 7 days) | Specificity (predictive specificity; common bloodstream infection pathogens; control samples without fever or infection within 7 days) | True negatives (negative control samples; any bacterium or yeast (Burkholderia, moulds, viruses and parasites excluded); control samples without fever or infection within 7 days) | True negatives (negative control samples; common bloodstream infection pathogens; control samples without fever or infection within 7 days) |
|---|---|---|---|---|
| Karius mcfDNA-Seq, all positive tests (Wolf et al. 2026)Evaluation | 82·7% | 88·9% | 134 | 144 |
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Predictive specificity in control samples (Wolf et al. 2026 Table 3)
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19 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation Any organism reported by the laboratory counts as positive. Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Episodes (Table 2) or control samples (Table 3), raw or with logical imputation as printed Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version Control plasma samples without fever or infection (Wolf et al. 2026) Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: inputs Leftover clinical plasma, microbial cell-free DNA Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: metric implementation Proportion of evaluable control samples in which mcfDNA-Seq detected no bacterium or yeast (any organism) or no common bloodstream infection pathogen. Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: population 162 control samples from the same population with no fever or infection within 7 days before or after collection Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: protocol id dna-pathogen-20261011-wolf2026-protocol-specificity Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: split Single cohort Context-only references | Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Limitations1 values
| Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study Table 3, rows 'All positive tests' Version: The Lancet Microbe 7:101312, published online 2026-03-02; PMC13154368 full-text XML (author manuscript) | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: dna-pathogen-20261011-wolf2026-eval-specificity-all