rewirebio.iobenchmarks
Dataset subset

unpaired-overall (SCMBench)

All six unpaired dataset splits (mean).

Evaluation results

17 evaluations · 17 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: bindSC (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.711 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across the five Muto-2021 batches (Yao not scored))
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

bindSC on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H6 (row 'bindSC', column 'unlabelled column H')
Configuration: Cobolt (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.369 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Cobolt on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H14 (row 'Cobolt', column 'unlabelled column H')
Configuration: FM-scVI (SCMBench adapter)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.57 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

FM-scVI on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H18 (row 'FM-scVI', column 'unlabelled column H')
Configuration: Geneformer (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.358 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across the five Muto-2021 batches (Yao not scored))
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H15 (row 'Geneformer', column 'unlabelled column H')
Configuration: GLUE (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.747 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GLUE on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H4 (row 'GLUE', column 'unlabelled column H')
Configuration: Harmony (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.607 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Harmony on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H17 (row 'Harmony', column 'unlabelled column H')
Configuration: iNMF (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.309 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

iNMF on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H16 (row 'iNMF', column 'unlabelled column H')
Configuration: LIGER (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.732 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LIGER on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H5 (row 'LIGER', column 'unlabelled column H')
Configuration: Pamona (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.534 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across the five Muto-2021 batches (Yao not scored))
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Pamona on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H11 (row 'Pamona', column 'unlabelled column H')
Configuration: PCA (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.532 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

PCA on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H12 (row 'PCA', column 'unlabelled column H')
Configuration: scFoundation (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.453 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across the five Muto-2021 batches (Yao not scored))
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scFoundation on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H13 (row 'scFoundation', column 'unlabelled column H')
Configuration: scGPT_zero (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.536 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across the five Muto-2021 batches (Yao not scored))
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scGPT_zero on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H10 (row 'scGPT_zero', column 'unlabelled column H')
Configuration: scJoint (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.809 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scJoint on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H2 (row 'scJoint', column 'unlabelled column H')
Configuration: scMoMaT (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.578 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across the five Muto-2021 batches (Yao not scored))
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scMoMaT on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H8 (row 'scMoMaT', column 'unlabelled column H')
Configuration: scVI (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.572 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scVI on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H9 (row 'scVI', column 'unlabelled column H')
Configuration: Seurat4 (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.759 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Seurat4 on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H3 (row 'Seurat4', column 'unlabelled column H')
Configuration: UCE (SCMBench)Protocol: SCMBench unpaired RNA-ATAC integration accuracy
Dataset subset: unpaired-overall (SCMBench)
0.588 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
unitless · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

UCE on SCMBench unpaired integration, unpaired-overall

lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy

Aggregation: Not reported

SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H7 (row 'UCE', column 'unlabelled column H')

Source checking is not independent reproduction. Release 2026-10-23-5347695500ed.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-23-5347695500ed · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
  • Compute requirements are estimated: not yet verified

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Subset and evaluation context

This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

8 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-23-5347695500ed
Property and statementOriginal source and locationReview and provenance
Source dataset label
unpaired-overall
Context-only references
SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Published article, Nature Communications 2026 (PMC13342640.1)
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_dataset_label

Source artifact SHA-256: 7aa2dbf1fc26bd602bf26e52c1061f91358a1c6cb389f57edc0ebfb0edc64f57

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source dataset label
unpaired-overall
Context-only references
SCMBench Supplementary Data 1 (methods and datasets)

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplementary Data 1 (MOESM3) of the published article
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_dataset_label

Source artifact SHA-256: 7287a457b1e856742a90043e96dc57b667210b28a8228d4d9a6de5d7156ecfb9

Hash scope: Hash scope not separately documented; inspect source record

Source location
Fig. 1b; Supplementary Data 1, sheet 'Dataset'
Context-only references
SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Published article, Nature Communications 2026 (PMC13342640.1)
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 7aa2dbf1fc26bd602bf26e52c1061f91358a1c6cb389f57edc0ebfb0edc64f57

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
Fig. 1b; Supplementary Data 1, sheet 'Dataset'
Context-only references
SCMBench Supplementary Data 1 (methods and datasets)

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplementary Data 1 (MOESM3) of the published article
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 7287a457b1e856742a90043e96dc57b667210b28a8228d4d9a6de5d7156ecfb9

Hash scope: Hash scope not separately documented; inspect source record

Description
All six unpaired dataset splits (mean).
Context-only references
SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Published article, Nature Communications 2026 (PMC13342640.1)
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 7aa2dbf1fc26bd602bf26e52c1061f91358a1c6cb389f57edc0ebfb0edc64f57

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
All six unpaired dataset splits (mean).
Context-only references
SCMBench Supplementary Data 1 (methods and datasets)

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplementary Data 1 (MOESM3) of the published article
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 7287a457b1e856742a90043e96dc57b667210b28a8228d4d9a6de5d7156ecfb9

Hash scope: Hash scope not separately documented; inspect source record

Name
unpaired-overall (SCMBench)
Context-only references
SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Published article, Nature Communications 2026 (PMC13342640.1)
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 7aa2dbf1fc26bd602bf26e52c1061f91358a1c6cb389f57edc0ebfb0edc64f57

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
unpaired-overall (SCMBench)
Context-only references
SCMBench Supplementary Data 1 (methods and datasets)

Original source ↗

Fig. 1b; Supplementary Data 1, sheet 'Dataset'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplementary Data 1 (MOESM3) of the published article
Retrieved: 2026-10-11T21:38:51Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 7287a457b1e856742a90043e96dc57b667210b28a8228d4d9a6de5d7156ecfb9

Hash scope: Hash scope not separately documented; inspect source record

Sources and history

Release 2026-10-23-5347695500ed · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: lit-cells-networks-20261011-scmbench-data-unpaired-overall

areas
single-cell
contexts
research
source dataset label
unpaired-overall
source locator
Fig. 1b; Supplementary Data 1, sheet 'Dataset'
missing metadata
version: reason: unreported
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