Configuration

LIGER (SCMBench)

Evidence concern: excluded from comparisons

Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H

'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows

In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20

Configuration of LIGER: default or tuned hyperparameters per the SCMBench setup; Defaults for R methods and methods without explicit hyperparameters; tuned otherwise.

13 evaluations · 13 results

Overview

An explanatory profile has not yet been reviewed for this record.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

13 evaluations · 13 results. Different protocols are not a single leaderboard.

Sorted by Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI)	Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets)
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, Muto-2021-batch-4 (SCMBench)	0.77 (best in column)	Not reported
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, Muto-2021-batch-3 (SCMBench)	0.766	Not reported
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, Muto-2021-batch-2 (SCMBench)	0.749	Not reported
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, Muto-2021-batch-5 (SCMBench)	0.738	Not reported
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, Muto-2021-batch-1 (SCMBench)	0.705	Not reported
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, Yao (SCMBench)	0.663	Not reported
LIGER (SCMBench)Evaluation	SCMBench paired RNA-ATAC integration accuracy, 10x-Multiome-Pbmc10k (SCMBench)	0.509	Not reported
LIGER (SCMBench)Evaluation	SCMBench paired RNA-ATAC integration accuracy, Ma-2020-batch-53 (SCMBench)	0.479	Not reported
LIGER (SCMBench)Evaluation	SCMBench paired RNA-ATAC integration accuracy, Ma-2020-batch-55 (SCMBench)	0.458	Not reported
LIGER (SCMBench)Evaluation	SCMBench paired RNA-ATAC integration accuracy, Ma-2020-batch-54 (SCMBench)	0.432	Not reported
LIGER (SCMBench)Evaluation	SCMBench paired RNA-ATAC integration accuracy, Chen-2019 (SCMBench)	0.407	Not reported
LIGER (SCMBench)Evaluation	SCMBench paired RNA-ATAC integration accuracy, paired-overall (SCMBench)	Not reported	0.457
LIGER (SCMBench)Evaluation	SCMBench unpaired RNA-ATAC integration accuracy, unpaired-overall (SCMBench)	Not reported	0.732 (best in column)

All 13 result rows with coverage, uncertainty and sources

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: LIGER (SCMBench)	Protocol: SCMBench paired RNA-ATAC integration accuracy Dataset subset: 10x-Multiome-Pbmc10k (SCMBench)	0.509 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench paired integration, 10x-Multiome-Pbmc10k lit-cells-networks-20261011-scmbench-protocol-paired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell B11 (row 'LIGER', column '10x-Multiome-Pbmc10k')
Configuration: LIGER (SCMBench)	Protocol: SCMBench paired RNA-ATAC integration accuracy Dataset subset: Chen-2019 (SCMBench)	0.407 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench paired integration, Chen-2019 lit-cells-networks-20261011-scmbench-protocol-paired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell C11 (row 'LIGER', column 'Chen-2019')
Configuration: LIGER (SCMBench)	Protocol: SCMBench paired RNA-ATAC integration accuracy Dataset subset: Ma-2020-batch-53 (SCMBench)	0.479 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench paired integration, Ma-2020-batch-53 lit-cells-networks-20261011-scmbench-protocol-paired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell D11 (row 'LIGER', column 'Ma-2020-batch-53')
Configuration: LIGER (SCMBench)	Protocol: SCMBench paired RNA-ATAC integration accuracy Dataset subset: Ma-2020-batch-54 (SCMBench)	0.432 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench paired integration, Ma-2020-batch-54 lit-cells-networks-20261011-scmbench-protocol-paired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell E11 (row 'LIGER', column 'Ma-2020-batch-54')
Configuration: LIGER (SCMBench)	Protocol: SCMBench paired RNA-ATAC integration accuracy Dataset subset: Ma-2020-batch-55 (SCMBench)	0.458 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench paired integration, Ma-2020-batch-55 lit-cells-networks-20261011-scmbench-protocol-paired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell F11 (row 'LIGER', column 'Ma-2020-batch-55')
Configuration: LIGER (SCMBench)	Protocol: SCMBench paired RNA-ATAC integration accuracy Dataset subset: paired-overall (SCMBench)	0.457 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench paired integration, paired-overall lit-cells-networks-20261011-scmbench-protocol-paired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G11 (row 'LIGER', column 'Overall')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: Muto-2021-batch-1 (SCMBench)	0.705 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, Muto-2021-batch-1 lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell C5 (row 'LIGER', column 'Muto-2021-batch-1')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: Muto-2021-batch-2 (SCMBench)	0.749 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, Muto-2021-batch-2 lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell D5 (row 'LIGER', column 'Muto-2021-batch-2')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: Muto-2021-batch-3 (SCMBench)	0.766 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, Muto-2021-batch-3 lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell E5 (row 'LIGER', column 'Muto-2021-batch-3')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: Muto-2021-batch-4 (SCMBench)	0.77 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, Muto-2021-batch-4 lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell F5 (row 'LIGER', column 'Muto-2021-batch-4')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: Muto-2021-batch-5 (SCMBench)	0.738 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, Muto-2021-batch-5 lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell G5 (row 'LIGER', column 'Muto-2021-batch-5')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: unpaired-overall (SCMBench)	0.732 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI; mean across datasets) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, unpaired-overall lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell H5 (row 'LIGER', column 'unlabelled column H')
Configuration: LIGER (SCMBench)	Protocol: SCMBench unpaired RNA-ATAC integration accuracy Dataset subset: Yao (SCMBench)	0.663 Scmbench integration accuracy (mean of MAP, NMI, ASW and ARI) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Evidence concern: excluded from comparisons Sheet 'unpaired_inte_overall' has no header for column H. Each H cell is the formula =AVERAGE(Bn:Gn), the mean of the dataset cells with values. Rows with a blank Yao cell (bindSC, scMoMaT, scGPT_zero, Pamona, scFoundation, Geneformer) average five datasets and the other rows six, so column H values are not comparable across all rows.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', row 1 and column H 'FM-scVI' is a different foundation model per dataset ('the best-performing foundation model combined with scVI, which varies across datasets', Fig. 2 legend), so its rows do not describe one fixed configuration.SCMBench Supplementary Data 2 (integration results) · Article Fig. 2 legend; Supplementary Data 2 'FM-scVI' rows In sheet 'paired_inte_overall' the scGPT row is scored on 10x-Multiome-Pbmc10k only; its Overall cell G20 (=AVERAGE(B20:F20)) is that single value, not a five-dataset mean, so it is not comparable with the other Overall values.SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'paired_inte_overall', cell G20 Methods, coverage and source LIGER on SCMBench unpaired integration, Yao lit-cells-networks-20261011-scmbench-protocol-unpaired-integration-accuracy Aggregation: Not reported SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration; SCMBench Supplementary Data 2 (integration results) · Supplementary Data 2, sheet 'unpaired_inte_overall', cell B5 (row 'LIGER', column 'Yao')

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SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration · Original source · Published article, Nature Communications 2026 (PMC13342640.1)
SCMBench Supplementary Data 2 (integration results) · Original source · Supplementary Data 2 (MOESM4) of the published article

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Technical metadata and extraction receipts

Stable ID: lit-cells-networks-20261011-scmbench-config-liger

areas: single-cell
contexts: research
method types: specialist
reported name: LIGER
foundation model eligible: false
hyperparameters: Defaults for R methods and methods without explicit hyperparameters; tuned otherwise (Methods 'Hyperparameter tuning')
source locator: Supplementary Data 2 method rows; Methods 'Benchmarking setup'
missing metadata: version: reason: unreported
provenance note: LIGER as run in SCMBench: default or tuned hyperparameters per the SCMBench setup.

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